JPS61168364A - 生体硬組織補綴材料の製造法 - Google Patents
生体硬組織補綴材料の製造法Info
- Publication number
- JPS61168364A JPS61168364A JP60007955A JP795585A JPS61168364A JP S61168364 A JPS61168364 A JP S61168364A JP 60007955 A JP60007955 A JP 60007955A JP 795585 A JP795585 A JP 795585A JP S61168364 A JPS61168364 A JP S61168364A
- Authority
- JP
- Japan
- Prior art keywords
- hydroxyapatite
- hard tissue
- living body
- prosthetic material
- synthetic hydroxyapatite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000463 material Substances 0.000 title claims description 22
- 238000004519 manufacturing process Methods 0.000 title claims description 12
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 31
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 30
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 14
- 239000000047 product Substances 0.000 claims description 13
- 239000000126 substance Substances 0.000 claims description 13
- 239000008187 granular material Substances 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 10
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 7
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 7
- 239000000920 calcium hydroxide Substances 0.000 claims description 7
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 7
- 238000006243 chemical reaction Methods 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 239000007795 chemical reaction product Substances 0.000 claims description 5
- 229910052586 apatite Inorganic materials 0.000 claims 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 description 16
- 210000000988 bone and bone Anatomy 0.000 description 15
- 239000002245 particle Substances 0.000 description 8
- 230000007547 defect Effects 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 238000002441 X-ray diffraction Methods 0.000 description 4
- 239000012620 biological material Substances 0.000 description 4
- 239000011575 calcium Substances 0.000 description 4
- 238000007796 conventional method Methods 0.000 description 3
- 239000012065 filter cake Substances 0.000 description 3
- 238000000465 moulding Methods 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 241000700157 Rattus norvegicus Species 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 230000001965 increasing effect Effects 0.000 description 2
- 235000012149 noodles Nutrition 0.000 description 2
- 230000011164 ossification Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000008929 regeneration Effects 0.000 description 2
- 238000011069 regeneration method Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000011343 solid material Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 208000018084 Bone neoplasm Diseases 0.000 description 1
- 230000000735 allogeneic effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- 239000012237 artificial material Substances 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 210000002449 bone cell Anatomy 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000005245 sintering Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000001308 synthesis method Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 239000011882 ultra-fine particle Substances 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60007955A JPS61168364A (ja) | 1985-01-18 | 1985-01-18 | 生体硬組織補綴材料の製造法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60007955A JPS61168364A (ja) | 1985-01-18 | 1985-01-18 | 生体硬組織補綴材料の製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61168364A true JPS61168364A (ja) | 1986-07-30 |
| JPS6314990B2 JPS6314990B2 (enrdf_load_stackoverflow) | 1988-04-02 |
Family
ID=11679912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60007955A Granted JPS61168364A (ja) | 1985-01-18 | 1985-01-18 | 生体硬組織補綴材料の製造法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS61168364A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03210271A (ja) * | 1990-01-12 | 1991-09-13 | Asahi Optical Co Ltd | リン酸カルシウム系生体材料の製造方法 |
-
1985
- 1985-01-18 JP JP60007955A patent/JPS61168364A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03210271A (ja) * | 1990-01-12 | 1991-09-13 | Asahi Optical Co Ltd | リン酸カルシウム系生体材料の製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6314990B2 (enrdf_load_stackoverflow) | 1988-04-02 |
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