JPS611438B2 - - Google Patents

Info

Publication number
JPS611438B2
JPS611438B2 JP51009948A JP994876A JPS611438B2 JP S611438 B2 JPS611438 B2 JP S611438B2 JP 51009948 A JP51009948 A JP 51009948A JP 994876 A JP994876 A JP 994876A JP S611438 B2 JPS611438 B2 JP S611438B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP51009948A
Other versions
JPS51101970A (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS51101970A publication Critical patent/JPS51101970A/ja
Publication of JPS611438B2 publication Critical patent/JPS611438B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP51009948A 1975-02-01 1976-01-31 Expired JPS611438B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4473/75A GB1536691A (en) 1975-02-01 1975-02-01 16-methyl-17-bromo-1,4-pregnadien-21-ol-3,20-dione compounds

Publications (2)

Publication Number Publication Date
JPS51101970A JPS51101970A (ja) 1976-09-08
JPS611438B2 true JPS611438B2 (ja) 1986-01-17

Family

ID=9777847

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51009948A Expired JPS611438B2 (ja) 1975-02-01 1976-01-31

Country Status (5)

Country Link
US (1) US4031080A (ja)
JP (1) JPS611438B2 (ja)
DE (1) DE2603545C3 (ja)
FR (1) FR2319368A1 (ja)
GB (1) GB1536691A (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS611699A (ja) * 1984-06-11 1986-01-07 ジ　アツプジヨン　カンパニー １６α‐メチル化法
US4704455A (en) * 1984-06-11 1987-11-03 The Upjohn Company 16α-methylatedΔ17(20)-corticoids
US4990612A (en) * 1984-06-11 1991-02-05 The Upjohn Company 16α-methylation process
CN102603842B (zh) * 2012-02-20 2013-10-23 湖南新合新生物医药有限公司 醋酸氢化可的松或其类似物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3261851A (en) * 1960-01-11 1966-07-19 Upjohn Co 16alpha-fluoromethyl compounds of the pregnane series and processes for the production thereof
US3350427A (en) * 1966-01-28 1967-10-31 Schering Corp Process for the dehydrohalogenation of steroids
DE2047105C3 (de) * 1970-09-18 1979-02-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen 17-Chlorsteroide und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
DE2603545B2 (de) 1979-08-16
US4031080A (en) 1977-06-21
FR2319368B1 (ja) 1978-11-03
FR2319368A1 (fr) 1977-02-25
GB1536691A (en) 1978-12-20
JPS51101970A (ja) 1976-09-08
DE2603545A1 (de) 1976-08-05
DE2603545C3 (de) 1980-04-24

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