JPS60139679A - ２−アリ−ルベンゾチアゾリン誘導体 - Google Patents

２−アリ−ルベンゾチアゾリン誘導体

Info

Publication number
JPS60139679A
JPS60139679A JP58251934A JP25193483A JPS60139679A JP S60139679 A JPS60139679 A JP S60139679A JP 58251934 A JP58251934 A JP 58251934A JP 25193483 A JP25193483 A JP 25193483A JP S60139679 A JPS60139679 A JP S60139679A
Authority
JP
Japan
Prior art keywords
group
formula
substituted
expressed
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58251934A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0545587B2 (enExample
Inventor
Junichi Iwao
岩尾　順一
Tadashi Iso
磯　正
Masayuki Ooya
大矢　正雪
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Priority to JP58251934A priority Critical patent/JPS60139679A/ja
Priority to US06/679,466 priority patent/US4547513A/en
Priority to GB08432034A priority patent/GB2152046B/en
Priority to DE19843446992 priority patent/DE3446992A1/de
Priority to KR1019840008366A priority patent/KR910004432B1/ko
Priority to ES539066A priority patent/ES539066A0/es
Priority to FR8419865A priority patent/FR2557109B1/fr
Priority to IT24269/84A priority patent/IT1179549B/it
Publication of JPS60139679A publication Critical patent/JPS60139679A/ja
Publication of JPH0545587B2 publication Critical patent/JPH0545587B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP58251934A 1983-12-27 1983-12-27 ２−アリ−ルベンゾチアゾリン誘導体 Granted JPS60139679A (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP58251934A JPS60139679A (ja) 1983-12-27 1983-12-27 ２−アリ−ルベンゾチアゾリン誘導体
US06/679,466 US4547513A (en) 1983-12-27 1984-12-07 2-Arylbenzothiazoline derivatives and their use in treating angina cordis
GB08432034A GB2152046B (en) 1983-12-27 1984-12-19 2-arylbenzothiazoline derivatives
DE19843446992 DE3446992A1 (de) 1983-12-27 1984-12-21 2-arylbenzothiazolin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
KR1019840008366A KR910004432B1 (ko) 1983-12-27 1984-12-26 2-아릴벤조티아졸린 유도체의 제조방법
ES539066A ES539066A0 (es) 1983-12-27 1984-12-26 Un procedimiento para la preparacion de nuevos derivados de benzotiazolina.
FR8419865A FR2557109B1 (fr) 1983-12-27 1984-12-27 Nouveaux derives de 2-arylbenzothiazoline utiles comme medicaments et procede pour leur preparation
IT24269/84A IT1179549B (it) 1983-12-27 1984-12-27 Derivati della 2-aribenzotiazolina

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58251934A JPS60139679A (ja) 1983-12-27 1983-12-27 ２−アリ−ルベンゾチアゾリン誘導体

Publications (2)

Publication Number Publication Date
JPS60139679A true JPS60139679A (ja) 1985-07-24
JPH0545587B2 JPH0545587B2 (enExample) 1993-07-09

Family

ID=17230142

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58251934A Granted JPS60139679A (ja) 1983-12-27 1983-12-27 ２−アリ−ルベンゾチアゾリン誘導体

Country Status (8)

Country Link
US (1) US4547513A (enExample)
JP (1) JPS60139679A (enExample)
KR (1) KR910004432B1 (enExample)
DE (1) DE3446992A1 (enExample)
ES (1) ES539066A0 (enExample)
FR (1) FR2557109B1 (enExample)
GB (1) GB2152046B (enExample)
IT (1) IT1179549B (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62221680A (ja) * 1986-03-19 1987-09-29 Santen Pharmaceut Co Ltd フエノキシアルキルアミン側鎖を有するベンゾチアゾリン誘導体
JPS62221679A (ja) * 1986-03-19 1987-09-29 Santen Pharmaceut Co Ltd ベンゾチアゾリン誘導体
WO2003082840A1 (fr) 2002-03-29 2003-10-09 Santen Pharmaceutical Co., Ltd. Agoniste du récepteur k-opioïde comprenant un dérivé de 2-phénylbenzothiazoline
WO2005002622A1 (ja) * 2003-07-04 2005-01-13 Santen Pharmaceutical Co., Ltd. 疼痛閾値低下抑制剤
US7642274B2 (en) 2003-07-04 2010-01-05 Santen Pharmaceutical Co., Ltd. Inhibitor of pain threshold decrease

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229398A (en) * 1990-02-27 1993-07-20 Adir Et Compagnie Aminomethylpiperidine compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5846079A (ja) * 1981-09-12 1983-03-17 Santen Pharmaceut Co Ltd ベンゾチアゾリン環を有するエ−テル類

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB825016A (en) * 1956-11-02 1959-12-09 Crookes Lab Ltd Therapeutic derivatives of aryl-benzthiazoles
US3720683A (en) * 1970-09-02 1973-03-13 Squibb & Sons Inc 2-phenyl-3-acylbenzothiazolines and their oxides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5846079A (ja) * 1981-09-12 1983-03-17 Santen Pharmaceut Co Ltd ベンゾチアゾリン環を有するエ−テル類

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62221680A (ja) * 1986-03-19 1987-09-29 Santen Pharmaceut Co Ltd フエノキシアルキルアミン側鎖を有するベンゾチアゾリン誘導体
JPS62221679A (ja) * 1986-03-19 1987-09-29 Santen Pharmaceut Co Ltd ベンゾチアゾリン誘導体
WO2003082840A1 (fr) 2002-03-29 2003-10-09 Santen Pharmaceutical Co., Ltd. Agoniste du récepteur k-opioïde comprenant un dérivé de 2-phénylbenzothiazoline
US7112598B2 (en) 2002-03-29 2006-09-26 Santen Pharmaceutical Co., Ltd. κ opioid receptor agonist comprising 2-phenylbenzothiazoline derivative
US7410987B2 (en) 2002-03-29 2008-08-12 Santen Pharmaceutical Co., Ltd. Method for treating pain or pruritis by administering κ-opioid receptor agonist comprising 2-phenylbenzothiazoline derivative
EP2042173A2 (en) 2002-03-29 2009-04-01 Santen Pharmaceutical Co., Ltd. Kappa-opioid receptor agonist comprising 2-phenylbenzothiazoline derivative
JP2009143940A (ja) * 2002-03-29 2009-07-02 Santen Pharmaceut Co Ltd ２−フェニルベンゾチアゾリン誘導体またはその塩類からなるκオピオイド受容体アゴニスト
WO2005002622A1 (ja) * 2003-07-04 2005-01-13 Santen Pharmaceutical Co., Ltd. 疼痛閾値低下抑制剤
US7642274B2 (en) 2003-07-04 2010-01-05 Santen Pharmaceutical Co., Ltd. Inhibitor of pain threshold decrease

Also Published As

Publication number Publication date
DE3446992A1 (de) 1985-07-04
FR2557109A1 (fr) 1985-06-28
FR2557109B1 (fr) 1987-09-04
KR910004432B1 (ko) 1991-06-27
IT1179549B (it) 1987-09-16
KR850004491A (ko) 1985-07-15
IT8424269A0 (it) 1984-12-27
ES8603850A1 (es) 1986-01-01
US4547513A (en) 1985-10-15
IT8424269A1 (it) 1986-06-27
GB2152046A (en) 1985-07-31
GB2152046B (en) 1987-06-03
GB8432034D0 (en) 1985-01-30
ES539066A0 (es) 1986-01-01
JPH0545587B2 (enExample) 1993-07-09

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