JPS60136506A - Deodorant - Google Patents

Abstract

PURPOSE:To provide a deodorant having high safety and excellent effect in food or cosmetic field, by using l-ascorbic acid, benzoic acid, gluconic acid, folic acid, nicotinic acid and/or their salts as active component. CONSTITUTION:One or more compounds selected from l-ascorbic acid, benzoic acid, gluconic acid, folic acid, niconitic acid and their salts are used as active components of the objective deodorant. The components may be diluted with a proper organic solvent or water to a proper concentration according to the use. The obtained deodorant has excellent effect to eliminate the offensive odor of ammonia, hydrogen sulfide, trimethylamine, methyl mercaptan, etc., and is free from the safety problem because all components of the deodorant are authorized food additives. It can be used in wide field, e.g. oral hygienic such as toothpaste, etc., food field such as masking agent for fish or animal meat, cosmetic field such as anhidrotics, and household field such as deodorant and perfumery for toilet.

Description

[Detailed description of the invention] The present invention relates to deodorizing and deodorizing agents, and specifically to foods.

This article relates to deodorizing and deodorizing agents useful in the field of cosmetics, etc.

As a deodorizing/deodorizing agent, activated carbon, glyoxalno 4'
In addition to those widely used, it has been reported that 3,4-dihydro-2H-bilane derivatives, amylose, sodium acrylate-acrylamide copolymers, etc. can be used as active ingredients for cosmetics. There is.

On the other hand, dimethylaminoallyl sulfonate, acrylamide, glucosamine, etc. are effective as deodorizing and deodorizing agents in the food field (Japanese Patent Laid-Open No. 48-23946
No. 1) and a breath odor remover containing cyclodextrin as an active ingredient (Japanese Unexamined Patent Publication No. 12270Q, 1983) have been proposed, and the development of safe and effective deodorizing/deodorizing agents has been delayed. Therefore, the emergence of useful products is strongly desired.

In view of these circumstances, the inventor of the present invention is working in the food field.

Highly safe as a deodorizing agent used in the cosmetics field.
We have conducted repeated studies to develop something that is also highly effective.

In Japan, we focused on the fact that vinegar is often used in cooking seafood, and after examining this from various angles, we found that organic acids not only act as flavor components and have preservative properties. I learned that it also helps improve the flavor.

In other words, it was discovered that certain organic acids are quite effective in deodorizing not only nitrogen-containing compounds that are malodorous components, but also money-producing compounds such as onions and garlic. Based on this, we continued our research into practical deodorants and their usage forms, and discovered that certain organic acids or their salts are useful among those permitted as food additives. This has led to the completion of the present invention.

In other words, the present invention is! - A deodorizing/deodorizing agent characterized by containing as an active ingredient one substance selected from the group consisting of ascorbic acid, benzoin, gluconic acid, pentofolic acid, nicotinic acid, and their salts. .

The organic acids and salts thereof used in the present invention were selected through numerous experiments.

For example, formic acid, lauric acid, linoleic acid, etc. do not have a sufficient deodorizing effect as described below, and cannot be used in the present invention. In the present invention, the above-mentioned organic acids and their salts can be used as they are as deodorizing/deodorizing agents, but they are used after being diluted with an organic solvent, water, etc. to an appropriate concentration, taking into consideration the purpose of use. In addition, depending on the organic acid, when making an aqueous solution, it is necessary to add an acid or an alkali to adjust the pH and dissolve it.If an organic solvent is used, it is allowed as a food additive. The material should be selected from among those permitted by the standards for raw materials and cosmetics.

The deodorizing/deodorizing agent of the present invention has a wide range of effects, and has excellent deodorizing effects on unpleasant odor substances such as ammonia, hydrogen sulfide, trimethylamine, and methyl mercaptan. Furthermore, all of the deodorizing and deodorizing agents of the present invention are permitted as food additives in Japan, so there is no need to worry about their safety.

Therefore, the deodorizing/deodorizing agent of the present invention is suitable for toothpaste.

Hygienic products such as mouthwash, chewing gum, and candy; food products such as fish and meat odor masking agents; cosmetic products such as antiperspirants, deodorants, deodorant soaps, shampoos, conditioners, and tonics; toilets, trash boxes, and other indoor uses It can be widely and suitably used in the household field such as deodorizing and aromatic agents; and in the industrial field such as factory odor removers. In addition, depending on the purpose of use, the deodorizing/deodorizing agent of the present invention may be used in combination with the deodorizing/deodorizing agent of Sen.

Next, the present invention will be explained in detail with reference to examples.

Examples 1 to 5 Deodorizing/deodorizing agents shown in Table 1 were obtained by diluting specified amino acids or salts thereof with water or ethanol. This deodorizing
A deodorization test was conducted on the deodorant. The results are shown in the second
It is shown in Table 6.

1 L-Ascorbic acid 109b aqueous solution 2 Sodium benzoate 〃 3 Gluconic acid 4 Folic acid 0.1% NaOH aqueous solution 5 Nicotinic acid 10% ethanol solution (40°C) Comparative example Activated carbon used as a deodorizer for refrigerators ((KYMCO) ", American Drug Two. Made by Boration) 1
A deodorization test was conducted using g. The results are shown in Tables 2-6.

Table 2 Example 1 100 tt 2 100 tt 3 100 〃4 100 /15 100 Comparative example 85.100 Ammonia removal rate measurement method: Prepare the sample so that it weighs 1 g in bulk, and add 10 (] ml)
Collect into a vial and seal it tightly. Ammonia 2.1g
Using a gas-tight syringe, inject the gas containing 1] into the vial. This is left at room temperature for 1δ, and after a predetermined time, the gases o and 3me in the vial are collected and injected into a gas chromatograph. On the other hand, as a control, a standard gas is injected into an empty, honey-filled vial from step 1 onwards, and the gas inside the vial is similarly sampled over time and injected into a gas chromatograph.

Determine the ammonia removal rate (@) of the sample from both measured values.The operating conditions of the gas chromatograph are as follows.

Filler = 1 romosorb 103 J (80/
100') Separation tube: inner diameter 3 mm, length 2 m, made of glass? ! 1IIIl degree: separation tube 140℃, inlet 15
0℃, detector 150℃ Gear gas: Helium 2
k! 7. /c1rL2 electromake: A, TT
ENUATTON 2.0URR, ENT 100mA
Recording paper feed speed 1rij: ] Ogi,/min.

GO-7A detector: TC
D Table 3 Examples] 7 12 15 26 62h 2 2 1
3 16 27 64 /l 3 9 14 18 31 45rt 4 17
21 24 28 68〃5 18 25 32 5
7 80 Comparative Example 20 52 60 80 95 Method for Measuring Hydrogen Sulfide Removal Rate: A sample is prepared so that the raw material has a concentration of 19, and the sample is added to a 10 () me capacity vial and sealed. A gas containing 1.7 ml of hydrogen sulfide is injected into the aforementioned vial using a gas-tight syringe. The following procedure is carried out in the same manner as the ammonia removal rate measurement method. Note that the operating conditions of the gas chromatograph are as follows.

Filler: 30% TC1 (P on Ohromosor
l) wAw (60780) Separation tube: Inner diameter 3, length 3
nt, made by Galanu Temperature: Separation tube 45℃, injection rl 10
0℃, detector 100℃Carrier gas: helium 0.8
kg/cIn2 Electrometer: A'l"l"E
NUAi'TON B, 0LI111 [Bow NT] 251
ηA recording paper feed speed: 10 V++, lI/min.

Model: RORI GO-7A 4 Extractor: TOI) Table 4 Example 1 100 〃 2 100 // 3 100 // 4 10 (1 N 5 100 Jt i&ir+l 95 1 00 Trimethylamine removal rate measurement method: Prepare the sample so that it weighs 1 g in bulk, collect it in a 100me vial, and seal it tightly.Trimethylamine 1.9
A gas containing m9 is injected into the aforementioned vial using a gas-tight syringe. The following procedure is carried out in the same manner as the ammonia removal rate measurement method. In addition, the operating conditions of the gas chromatograph are as follows.

Filler: “Obromosorb 103 J (8
0/100) Separation tube: inner diameter 31n1η, length 2m, made of glass Temperature: Separation tube 180℃, injection port 250'C, detector 250'C Carrier gas: Nitrogen 2kg/crIL
2 Gas pressure: Hydrogen 0-6kg/g12. Air (1, 51<
9/cm 2'f-ref) 07'-1-: , A'
J'TENIL4'I'TON 32, n, ANGE
102 Recording paper feed speed: 10, Guni/In 1
n - Machine type: Roshi GO-71 Detector: FID Table 5 Megul mercabutane removal rate (%) Elapsed time (minutes) Sample 1 3 5 II 20 Example] 13 14 15 20 32// 2 1
．． 7 22 35 4.5 551/ 3 30 42
52 65 701/ 4 18 32 62 70
861/ 5- 25 45 52 68 72 Comparative example 40 80 100 Methyl mercaptan removal rate/measuring method: Prepare the sample so that the original weight is 19, collect it in a 100me vial, and seal it. Methyl mercaftan 0.
A gas containing 89m9 is injected into the aforementioned vial using a gas-tight syringe. The following procedure is carried out in the same manner as the ammonia removal rate measurement method. In addition, the operating conditions of the Ganu chromatograph are as follows.

Charge J5i agent: 30% 'l'c! EP on Ch.
romosorb wAw (60/80) Separation tube: Inner diameter 3mm, length 2m, made of glass Temperature: Separation tube 120℃,
Inlet 250°C1 Detector 2500C#Y1J7-Gas: Nitrogen 0.7 kg/cm2 Gas pressure: Hydrogen 0.5 kg
/cIIL2. Air 1.0 kg/cm2: Lref) I
ff meter: TLANGE 32. 5ENSI
TIVPTY 102 Chart paper feed speed: 10 m/m
1 n.

11U type: Shimadzu GO-4CM Detector: FTl) Table 6 Example 1 12 13 13 15 18ri 2 15
17 19 i9 19ZI3 8 10' 10
1010 // 4 75 89 909195 tt 5 828789 8g 92 Comparison 4A 8 (+ 95 99100 Acetic acid removal rate measurement method: Prepare the sample so that it weighs 1 g in bulk 11.1o.

Collect into a ml vial and seal. Acetic acid Q, 3+
Inject the gas containing a) into the Novial vial using a gas-tight syringe. The following procedure is carried out in the same manner as the ammonia removal rate measurement method. In addition, the operating conditions of the gas chromatograph are as follows.

Filler: 10%,'&'AL-Mon 5hinal
ite TPA (80/100) Separation tube: 3 inner diameter,
Length 27n, made of glass Temperature: Separation tube 170°C, Inlet 250'C, Detector 250°C Carrier gas dinitrogen 1.
3kg/cIIL2 gas pressure: Hydrogen 0.5 kg/cIr
L2. Air 1.0kg/cm2 electrometer:
, RANGE 8, 5ENSITIVITY 10
2 Recording paper feed speed: 1 Q mm/mjn.

Model: Ro Ri GO-4C! M' Detector: li'ID Application Example 1 Using the deodorizing/deodorizing agent obtained in Example, chewing gum was manufactured according to the following formulation.

Gum base 20% Sugar 60 Water Candy 15 Water 4% Inventive product * 1 rice cake * 1 for each example! ! A sensory test on bad breath was conducted on this chewing gum. As a result, it was found that it had good effects as shown in Table 7. In addition, the sensory evaluation of the bad breath removal effect was performed by the following method.

In order to comprehensively examine the halitosis removal effect, artificial Ll odor,
In vitro sensory tests were conducted for tobacco and garlic odors. Artificial bad breath was prepared using hydrogen sulfide, methyl mercaptan, and dimethyl sulfide, which are the three major components of bad breath, in the following manner.

■ Blow hydrogen sulfide gas into 200 ml of pure water at 15°C for about 1 hour to saturate it with hydrogen sulfide.

(2) 200 m of dimethyl sulfide and 200 m9 of methyl mercaptan were added to 100 m1 of a saturated hydrogen sulfide solution and mixed well to prepare an artificial bad breath liquid.

Dilute the artificial bad breath liquid 100 times with pure water, then dilute the 101n
Gargle with l for 1 minute, take the exhaled breath 3e after iM into a 31 volume odor bag (manufactured by Omi Odor Air Service Co., Ltd.),
The evaluation score was 0, and after that, chewing gum containing various active ingredients was chewed for 3 minutes, and the breath was taken and evaluated. 〇Tobacco odor is 3 highlights from the base of the filter 2 (
Same friend holder up to 1m long (Lotte Electronics)
Co., Ltd.) and smoked 3 cigarettes in 3 minutes, and the exhaled air 37
! was placed in an odor bag and given an evaluation score of 0. After that, chew chewing gum containing various active ingredients for 3 minutes, and exhale 3
! ! The 1° garlic odor evaluated is garlic (mink (
After slicing and drying the garlic, diameter 2-3 III
Place 50g of the powder into milk and boil it in warm water (approximately 40°C).
) Add 200nl of garlic, rub well for 10 minutes, then strain through gauze to obtain an extract of 160g of garlic. Dilute this extract 20 times with pure water and hold 16ml of it in your mouth for 5 minutes. After that, take the exhaled breath 31 in a smell bag and get d・F score 0.
What happened? Thereafter, chewing gum containing various active ingredients was chewed for 3 minutes, and the breath 31 was evaluated again using 51 bags.

The deodorizing effect was evaluated by five expert panelists as shown below.
f' (Ill direction i:= KL, each score is 5
Evaluation in stages l1. Ta.

1 0's 1/10O') 9 degrees Strong smell 2 ()'s I/
Concentration of 100 Easily detectable odor 1/30 of 30
Concentration of 0 Odor table 7 that tells you what the smell is Fire hW 9+ 3.0 3°0 3. .

//, i 2.8 2°6 2.5 〃 5 2.5 2°5 2.5 Control* 2.4 2.6 □, 3 In this formulation, water was added instead of the inventive product Product Application Example 2 A shampoo was manufactured using gluconic acid (Example 3) and folic acid (Example 4) according to the following formulation.

Lauryl sulfate triethanolamine salt (30% aqueous solution)
25 φ Coconut oil fatty acid monoethanolamide Section 6 ED'l! , A ・2Na 0.1% Inventive product 1.
09IJ Water 47. ! 195 This shampoo was evaluated for sweat odor removal by 10 expert panelists according to the evaluation method shown below and compared with a control product.
゜Completely deodorized... +2 Slightly deodorized... 11 Unable to judge...0 Slight sweat odor remains... -1 Not deodorized at all... - 2 The evaluation results are shown in Table 8. As is clear from the table, the shampoo containing the product of the present invention has an excellent sweat odor removal effect.

Table 8 Example 3 +2 +1 +2 +2 +1 +2 +2
+2+2 +1 1-1.7II 4 +2+1+2
+1 -1-1 +1 +1 +1 +1 +2 +1
．． 3 controls Old +1000.0 +10-1-1 +0.
1+ Reference example using water instead of the product of the present invention Deodorization test conducted in the same manner as in the example for formic acid (10% aqueous solution), lauric acid (10% ethanol solution) and linoleic acid (1'OS ethanol bath solution) I did this. As a result, these organic acids showed deodorizing effects against ammonia and trimethylamine1-, but did not show deodorizing effects against other substances as shown below, and were judged to have no deodorizing effect in a comprehensive evaluation. It was done.

Table 9

Claims (1)

[Claims] l-Ascorbic acid, benzoic acid, gluconic acid. A deodorizing/deodorizing agent characterized by containing as an active ingredient at least one substance selected from the group consisting of folic acid, nicotinic acid, and salts thereof.