JPS59500564A - 流動及び圧縮特性の改良された乾燥粉末組成物とその製造法 - Google Patents
流動及び圧縮特性の改良された乾燥粉末組成物とその製造法Info
- Publication number
- JPS59500564A JPS59500564A JP58501824A JP50182483A JPS59500564A JP S59500564 A JPS59500564 A JP S59500564A JP 58501824 A JP58501824 A JP 58501824A JP 50182483 A JP50182483 A JP 50182483A JP S59500564 A JPS59500564 A JP S59500564A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- crystalline
- ascorbic acid
- dry powder
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 150000002739 metals Chemical class 0.000 description 1
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- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 230000010627 oxidative phosphorylation Effects 0.000 description 1
- 229940014662 pantothenate Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US371003 | 1982-04-22 | ||
| US06/371,003 US4454125A (en) | 1982-04-22 | 1982-04-22 | Dry powder formulations having improved flow and compressibility characteristics, and method for the preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59500564A true JPS59500564A (ja) | 1984-04-05 |
| JPH0516404B2 JPH0516404B2 (OSRAM) | 1993-03-04 |
Family
ID=23462101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58501824A Granted JPS59500564A (ja) | 1982-04-22 | 1983-04-20 | 流動及び圧縮特性の改良された乾燥粉末組成物とその製造法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4454125A (OSRAM) |
| EP (1) | EP0105924B1 (OSRAM) |
| JP (1) | JPS59500564A (OSRAM) |
| CA (1) | CA1209041A (OSRAM) |
| DE (1) | DE3382047D1 (OSRAM) |
| WO (1) | WO1983003757A1 (OSRAM) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4533674A (en) * | 1983-10-24 | 1985-08-06 | Basf Wyandotte Corporation | Process for preparing a sugar and starch free spray-dried vitamin C powder containing 90 percent ascorbic acid |
| NZ217821A (en) * | 1985-10-10 | 1989-07-27 | Biotech Australia Pty Ltd | Oral delivery system; complex of active agent and vitamin b12 or analogue thereof |
| US5807832A (en) * | 1987-06-09 | 1998-09-15 | Biotech Australia Pty Limited | Oral delivery of biologically active substances bound to vitamin B12 |
| US5122369A (en) * | 1990-03-30 | 1992-06-16 | Harmony Health Products, Inc. | Nutrient composition for preventing hair loss |
| ATE117202T1 (de) * | 1991-01-28 | 1995-02-15 | Hoffmann La Roche | Vitamin enthaltende formulierungen und deren herstellung. |
| DK0531497T3 (da) * | 1991-04-02 | 1998-03-23 | Biotech Australia Pty Ltd | Orale indgivelsessystemer til mikropartikler |
| JPH07503010A (ja) * | 1992-01-06 | 1995-03-30 | ヘルス・メインテナンス・プログラムズ，インコーポレイテッド | 薬学活性酸化防止剤含有組成物並びに該組成物を使用する血管形成後の再狭窄予防および治療方法 |
| US5292534A (en) * | 1992-03-25 | 1994-03-08 | Valentine Enterprises, Inc. | Sustained release composition and method utilizing xanthan gum and an active ingredient |
| US5204114A (en) * | 1992-03-30 | 1993-04-20 | Health Maintenance Programs, Inc. | Methods of manufacturing high dosage glutathione the tablets and capsules produced thereby |
| US5288510A (en) * | 1992-05-18 | 1994-02-22 | George Gregory | Palatable low salt substitutes |
| US6764693B1 (en) | 1992-12-11 | 2004-07-20 | Amaox, Ltd. | Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants |
| CZ352097A3 (cs) * | 1995-05-09 | 1998-04-15 | Colorcon Limited | Způsob a materiál pro elektrostatické potahování jádra farmaceutických tablet |
| US7008668B2 (en) * | 1995-05-09 | 2006-03-07 | Phoqus Pharmaceuticals Limited | Powder coating composition for electrostatic coating of pharmaceutical substrates |
| GB9623634D0 (en) * | 1996-11-13 | 1997-01-08 | Bpsi Holdings Inc | Method and apparatus for the coating of substrates for pharmaceutical use |
| CA2276183C (en) | 1996-12-31 | 2009-06-09 | Antioxidant Pharmaceuticals Corporation | Pharmaceutical preparations of glutathione and methods of administration thereof |
| GB0002305D0 (en) * | 2000-02-01 | 2000-03-22 | Phoqus Limited | Power material for electrostatic application |
| US6890918B2 (en) * | 2001-04-30 | 2005-05-10 | Shire Laboratories, Inc. | Pharmaceutical compositions including ACE/NEP inhibitors and bioavailability enhancers |
| GB2420297B (en) * | 2003-06-18 | 2006-11-15 | Phoqus Pharmaceuticals Ltd | Method and apparatus for the application of powder material to substrates |
| GB0330171D0 (en) * | 2003-12-30 | 2004-02-04 | Phoqus Pharmaceuticals Ltd | Method and apparatus for the application of powder material to substrates |
| GB0407312D0 (en) * | 2004-03-31 | 2004-05-05 | Phoqus Pharmaceuticals Ltd | Method and apparatus for the application of powder material to substrates |
| US8075910B2 (en) * | 2004-05-20 | 2011-12-13 | Pbm Pharmaceuticals, Inc. | Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions |
| JP5795133B1 (ja) * | 2015-03-31 | 2015-10-14 | 孝則 太田 | アスコルビン酸分散材、及びその製造方法 |
| US20160367620A1 (en) | 2015-06-19 | 2016-12-22 | Harry B. Demopoulos | Glutathione |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2477491A (en) * | 1947-08-18 | 1949-07-26 | Lilly Co Eli | Vitamin compositions |
| US2816854A (en) * | 1953-05-26 | 1957-12-17 | Ralph H Gross | Nutrition aid |
| US3740432A (en) * | 1971-02-16 | 1973-06-19 | Hoffmann La Roche | Vitamin complexes of niacinamide,riboflavin and sodium ascorbate |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3160564A (en) * | 1961-12-19 | 1964-12-08 | Merck & Co Inc | Multi-vitamin composition containing pantothenamide |
| US3175948A (en) * | 1963-01-10 | 1965-03-30 | Hoffmann La Roche | Multivitamin tablets and premixes |
-
1982
- 1982-04-22 US US06/371,003 patent/US4454125A/en not_active Expired - Lifetime
-
1983
- 1983-04-20 JP JP58501824A patent/JPS59500564A/ja active Granted
- 1983-04-20 DE DE8383901783T patent/DE3382047D1/de not_active Expired - Lifetime
- 1983-04-20 EP EP83901783A patent/EP0105924B1/en not_active Expired
- 1983-04-20 WO PCT/US1983/000587 patent/WO1983003757A1/en not_active Ceased
- 1983-04-21 CA CA000426439A patent/CA1209041A/en not_active Expired
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2477491A (en) * | 1947-08-18 | 1949-07-26 | Lilly Co Eli | Vitamin compositions |
| US2816854A (en) * | 1953-05-26 | 1957-12-17 | Ralph H Gross | Nutrition aid |
| US3740432A (en) * | 1971-02-16 | 1973-06-19 | Hoffmann La Roche | Vitamin complexes of niacinamide,riboflavin and sodium ascorbate |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1209041A (en) | 1986-08-05 |
| US4454125A (en) | 1984-06-12 |
| DE3382047D1 (de) | 1991-01-17 |
| EP0105924A4 (en) | 1986-02-20 |
| EP0105924B1 (en) | 1990-12-05 |
| JPH0516404B2 (OSRAM) | 1993-03-04 |
| EP0105924A1 (en) | 1984-04-25 |
| WO1983003757A1 (en) | 1983-11-10 |
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