JPS5925728A - Apparatus for measuring hardness of living body tissue - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention involves applying a pressure transmission medium to a living body, adding imaging,
This invention relates to a biological tissue hardness measuring device that measures the softness or hardness of a biological tissue based on the amount of displacement of a pressure transmission medium and the applied pressure.

This glazed device allows constant oxidation of the hardness of a living body in place of a doctor's palpation, but it is necessary to insert a pressure transmission medium inside for measurements in obstetrics and lumen instruments. For this reason, it is well known that a rubber film was attached to the tip of a rod that was attached to the tip of the dwire to apply air vibration to the rod, but the support of the rod and its surrounding structure In addition, because the vibration frequency must be lowered to correspond to the weight and length of the rod, it is easy for biological micromotions to enter the frequency range to be measured, resulting in low measurement accuracy and the need to lower the vibration frequency in response to the weight and length of the rod. Properties could not be obtained/It was also inconvenient to seek co-J malleability of living organisms. .

Therefore, the present invention makes it possible to apply vibrations to a wide 41-9-tonne area with a simple forgery, and also to easily measure the calm frequency range. The hardness of living tissue is 6i11') JF equipment provided by the Japanese flute - for the purpose of noise. .

Next, explanation will be given based on an example of C (Kienori) τ diagram.

First, the hardness measuring device according to the embodiment of the present invention includes a probe that applies vibration to a living body and detects the response/response signal, a circuit device that processes the detection signal and drives the glove, and a circuit device that processes the detection signal and drives the glove. It consists of an output device for displaying or recording.

FIG. 1 shows one of these gloves, and in the same figure, 1 is a vibration-applying member such as a moving coil type that applies vibration to a truncated cone-shaped driving body 3 made of a non-magnetic phase such as a duralumin plate. It is a vessel. A ring 5 of a non-magnetic phase is attached above the container 2, and another ring 6 of a non-magnetic phase is fitted above this. A watertight diaphragm 9 is inserted through an elastic body into an oval cavity 8 formed along the inner wall of the ring 6, and a tire flammable diaphragm using a strain cage, for example, is inserted into the cavity 10 between the rings 5 and 6. A displacement lid cover 11 for detecting the amount of displacement of 9 is inserted in a wet state. Then, as for the lotus 11'V of this displacement sensor 11, there is a screw 1 with a flat tip along with the diaphragm 9.
3 is fixed to the driving body 3. Furthermore, ring 6
A structure 16 to which deaerated water is supplied by a cock 15 and a cavity 18 in which a pressure sensor 17 is installed are communicated from the outer wall to the inner wall. On the upper surface of the ring 6, a ring 20 made of a transparent material, for example, acrylic, is attached by pasting or screwing from above. A pipe 22 made of stainless steel and having an open lower part is removably fitted into this ring 20 by placing an elastic body 2 4 ft ft halfway from the upper part on the inner wall of the ring 20, and the inner diameter of the ring 20 is This matches the inner diameter of ring 6. pipe 2
The outer diameter of the link 20 is, for example, 10 nun 8 If, and the height of the protruding portion from the link 20 is, for example, 200 mm. Above the first ζ ignition 22, an O-link 23 and a washer/yarn 24 are installed in the notch part, and a water-repellent elastic film, for example, a polyurethane film 25 is placed on the wax/yasha 24. When the cap 26 is screwed on, the elastic membrane 25 at the inner end of the pipe 22 is pressed upwards above the upper end of the cap 26. This shows the circuit configuration and output device of the invention, and first, a sine wave oscillator 81 with a frequency oJ
and a power amplifier 32 for the oscillation signal constitute a drive circuit for the vibration adder 1. Also, an amplifier 41 that amplifies the detection signal of the displacement sensor 11, an i-pass filter 42 that selects only the vibrational displacement signal, a rectifier 43 that converts the vibration component that has passed into a DC signal, and a DC amplifier. 44, a corresponding amplifier 45 belonging to the pressure sensor 17, a high-panu filter 46, a rectifier 47, a DC amplifier 48, and an analog division for dividing the output signal of the DC amplifier 44 by the output signal of the DC amplifier 48. A circuit 49, a low-pass filter 50 that removes noise generated during division operation and outputs a compliance signal, and outputs a static pressure signal by passing only the DC component from the output signal of the amplifier 45. The low-pass filter 51 constitutes a signal processing circuit for both sensors 11 and 17. ,,60 fr,i: An output device for displaying, metering or recording static pressure and compliance information generated by this signal processing circuit, such as a pen recorder.

When making measurements, open the cock 15 and pour deaerated water 28 into groove 1.
6 through the cylindrical cavity inside the ring 6 and the pipe 22
Fill the pipe 22 with new water, or check the degassed water 28 for foaming etc. through the transparent ring 20 and remove the water from the pipe 22 as necessary.
Remove the pipe 22, υ, and ring 6.20, and replace the degassed water 28. 1. Compliance regarding the vibrating string related to measurement from the drive body 3 to the living body in this state. As shown in Fig. 3, the equivalent circuit is the compliance C1 of the rigid vibrating parts such as the driver 3 and the screw 13 that are applied in series to the vibration pressure, the compliance C4 of the cow body tissue, and the compliance C4 that is applied in series to the vibration pressure. Conclave 1 A/S C3 of lyu membrane 25, and the escape r'no'/S C2 of Pap 22 that is added in parallel to these C3 and C4, and the living body that strikes the sword. 1, which cannot be ignored by adjusting the conformance C4 of 1, and becomes a column circuit.
111 bodies are sent to the 1st corner and made into C4-U state-c
Find the first straight of C2 based on the vibration 11- and the vibration between points h-A', and then the bullet 19:11! l! The value of C3 is also determined by calculating the composite value of C2 and C3 in the state of 25 Kefri January IJ and C4φ. Then, the elastic membrane 25 is applied to the living tissue to obtain a composite value of C2 to C4, and C4 is calculated based on the known values of 02 and C3.

Specifically, first, by setting the frequency of the excavator 31 and driving the vibration adder 1 with the amplified signal, the driver 3
vibrates the diaphragm 9 and the tip rfu of the screw 13 to vibrate the degassed water at a set frequency. Therefore, the pressure sensor 17 and the displacement sensor 10 measure the static pressure and static pressure displacement corresponding to the pressing force of the elastic membrane 25 on the object to be measured, as well as the vibration pressure applied to the object and its compliance. The amount of vibration displacement is detected respectively. First, after the detected displacement signal r is amplified by the amplification IM device 41, only the imaging component that is safe for compliance measurement is passed through the no-pass filter 42, and then the rectifier 43
After being absorbed into the DC signal, the DC amplifier 44''
C'' is transmitted and supplied to the analog divider circuit 49 as a gap calculation signal.On the other hand, the detected pressure signal is...
The ζ filter 46 selects and intensifies only the vibration component tS, converts it, and supplies it as a divisor signal to the analog divider circuit 49.
Then, a synthetic compliance performance related to the object to be touched is performed automatically one after another, and a compliance signal is output from the low-pass filter 50. By selecting the vertical θIC1 component of the utility information output from the amplifier 45 by the low-pass filter 51, the static pressure Gi is output. Confliance Hakuq and static pressure Shingetsu are output device 6
0, and from the amplitude of each house, the composite compliance beyond the diaphragm 9 for the unmeasured valley is measured, and at the same time, the static pressure of the air and water at the time of the measurement is also known.
, In this way, we went over jJ + the required frequency band and static pressure axis seven times, measured C2' and C3 in advance, and calculated each l.
3゜biological body) + li EU (i'nocon compliance measurement field j
Similarly, the output device 60 measures the static pressure to adjust the i'lll lf force of the elastic membrane 25, and calculates the composite value of C2 to C4 over a predetermined frequency or frequency band. 0 based on the measured and known C2 and C3 values.
Calculate 4.

Figure 4 shows that in order to confirm the effect of the hardness measuring device described above, we added an amount of RT silicone rubber additive with similar mechanical behavior to the soft tissue of a living body and changed its stiffness (compliance). The stiffness measurement value changes with high accuracy in response to hardness. Figure 5 shows measurements of the resonance characteristics of recon combs with different hardnesses, in which not only the hardness itself but also the resonance points shifted corresponding to the hardness were measured.

Figure 6 shows 11〒 two healthy women on the bone (actual 11i
131) and two female patients with edema (dotted line), and it was confirmed that edema can be detected from the hardness and resonance frequency of living tissues.

The liquid to be filled into the pipe 22 is preferably water, especially degassed water without elasticity, from the viewpoint of viscosity coefficient, easy availability, harmlessness to living organisms, chemical inertness, etc. It is also possible to use other liquids with viscosity coefficients lower than that of . Incidentally, the viscosity coefficient of water is considered to be on the order of 10-4 compared to the sliding viscosity of living organisms, but even liquids on the order of 10-2 can be measured with high precision. As a circuit device, it is also possible to output a stiffness signal by replacing the input signals in the divider circuit 49, and to add the output No. 1g of the switched double width device 44 and 48 directly to the output device and perform the division separately. Furthermore, when C2 and C3 are executed several times, an arithmetic circuit that automatically calculates C4 can be installed, and a digital printer can be used as an output device to record the value in a numerical format. 3. Regarding the shape of the pipe, compared to the measurement place, it is also possible to use a different shape instead of a thin tube. In order to use a liquid, it becomes possible to apply pressure to the living body of the gods =ls lX1- with an intermediate structure, and the hardness side rectangle of the number range ILl'l is iJ Dragon. In order to become clinically applicable, it can also be used outside of obstetrics because it can be used to control and quickly turn 1%, and to form a medium 1 impalp into a cape 1 shape!
11) J″ Hatake!! Isao・Noibo）ship i11.11
The j center of the constant h'\ is also changed to 1j1i (・Gonaru, 1/1.1 So1's total j1''i Invention Figure 1 shows the present invention yc hard j and 111 door device h' Figure 2 is a cross-sectional view of the flow) part, showing the circuit device side and the circuit configuration of the output device j'91j.
1shi: U:1. −.

[1st vibration E]Conogly j'nos's equal circuit from the excitation device to the object to be contacted, 11/and Figures 4 to 61-1
6;1, Wood I:, light effect (1'(II 'Ag-
J'ru 1c's visit' house futa o/Jgu (to) -3°

Claims (2)

[Claims] (1) A pipe equipped with an elastic membrane at the tip and filled with a liquid having a viscosity coefficient smaller than that of a living body, a vibration adder that applies vibrations to the liquid from the rear of the pipe via a diacrum, and A biological tissue hardness measuring device comprising: a displacement sensor that detects the amount of displacement; and a pressure sensor that detects the pressure of the liquid. (2) The biological tissue hardness measuring device according to claim 1, wherein the liquid is water.