JPS59232069A - Egg having antiaging activity - Google Patents

Abstract

PURPOSE:To delay the aging of human body, by taking poultry eggs having high iodine content as daily food. CONSTITUTION:An iodine compound and/or marine algae are added to the feed of poultry to an extent to exceed the normal iodine requirement of the poultry, and egg-laying poultry is fed with the feed to obtain eggs containing >=300mug of iodine. The iodine compound is preferably calcium iodate in view of the health of the poultry and the transferability of iodine to the egg. The amount of iodine in the feed is adjusted to 50-2,500ppm, especially 50-150ppm. When an iodine compound is used in combination with marine algae, preferably 40-100ppm and 10-50ppm of the iodine are originated from the iodine compound and the marine algae, respectively. Daily use of the egg as a food prevents the hypothyroidism and arteriosclerosis, and reduces the contents of cholesterol and lipid peroxide in the brain.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to eggs that contain a high amount of iodine and that, when ingested continuously, have the effect of delaying the aging of the human body, that is, have an anti-aging effect.

Even in modern society, where medical science and pharmaceutical science have advanced, major issues that still remain include ``illness and death due to aging'' and ``senility from the elderly.''

Aging is the decline of vital functions and is a major impediment to a healthy life, but measures against aging include paying attention to health management to suppress aging caused by disease, that is, pathological aging.
Prolonging physiological aging through sustained moderate physical exercise;
There are ways to improve your living environment to eliminate stress in your mind and body, continue appropriate mental activities to prevent decline in mental function, and improve your eating habits and life cycle. The composition and quality of food, which has a deep relationship with human health, plays an important role in preventing aging as well as its nutritional role.

In particular, the ``sluggishness'' (softening of the brain) in the elderly, which is a major problem in an aging society, is thought to be related to an increase in cholesterol and a substance called ribofuscin, which contains a lot of lipid peroxide, in the brain. It is also said that this kind of lipid peroxide is a substance deeply related to the development of arteriosclerosis and cancer.

Under these circumstances, the inventor has conducted extensive research into the relationship between the content of food, its nutritional role, and aging, and has found that:
Continuously ingesting bird eggs that contain high iodine can slow aging by suppressing the decline of thyroid function and arteriosclerosis during aging, as well as reducing the cholesterol content and lipid peroxide content in the brain. They found that it is effective and completed the present invention.

According to the research conducted by the present inventor, there have been no reports that iodine or foods containing high iodine have an effect of delaying aging, and the present invention can be said to be a pioneering invention in this field.

The present invention will be explained in detail below. The eggs having anti-aging effects of the present invention are eggs containing 300 p, g-E or more of iodine, and are usually obtained as follows.

In other words, iodine compounds such as calcium iodate, potassium iodate, potassium iodide, sodium iodide, copper iodide, thymol iodide, calcium iotobihemate, short salicylic acid, calcium periodate, or kelp, wakame, etc. Seaweed or processed products containing a large amount of iodine are added to feed so that the amount exceeds the normal iodine requirement of birds, and the feed is fed to egg-laying birds to increase the iodine content in their eggs. It is.

At this time, it is preferable to use calcium iodate as the iodine compound in terms of the health of the birds and the transfer rate of iodine to eggs, and it is even better to use seaweed such as kelp in combination. The amount of iodine administered to birds varies depending on the type of bird, such as chickens and cranes, but it is usually 50 to 2,500 iodine in the feed.
ppm, preferably 50 to 150 ppm of iodine is added and blended. When using the above iodine compound and seaweed together, the iodine from the iodine compound is 40 to 1
00 ppm, iodine from seaweed is 10-50
It is particularly preferable to blend the amount so that the amount becomes ppm.

When an iodine compound or a substance containing a large amount of iodine is administered to birds in this manner, the desired eggs containing high iodine will be produced about one week later. For example, in the case of laying hens, if feed containing about 50 ppm of iodine is fed, eggs containing about 300 u, g of iodine per egg will be produced, and the feed will contain about loop ppm of iodine. Approximately 600~ per egg when feed is administered
If eggs containing 80 ogg of iodine are produced, and feed containing about 2,500 ppm of iodine is fed, each egg contains about 4,000 to 5,000 It g.
Eggs containing iodine are produced.

The eggs obtained in this way can be used as they are, but the yolk part, which is most effective, can also be separated and only the yolk part used as the active ingredient. In addition, the iodine-rich eggs and their yolks may be processed by drying, concentrating, powdering, granulating, etc., and may be mixed with various excipients, binders, etc. to form tablets, powders, etc. It can also be used in the form

The anti-aging egg with high iodine content according to the present invention has no particular safety problem since the bird's body plays the role of a biological filter. It is preferable to take a fixed amount every day, usually at mealtimes or before and after meals. According to the present invention, 300 pLg of iodine in eggs is normally given to adults.
Aging can be delayed by administering an amount of ~1500 JLg. Specifically, - The daily intake should be 1 to 3 eggs containing about 300 to 1500 ILg of iodine, and granules of whole eggs or their yolks containing high iodine. 300-300 mg/day depending on the iodine content of the granules.
The dose of granules should be adjusted so that about 1,500 kg of iodine is ingested.

In this way, continuous intake or administration of eggs with high iodine content delays aging, prevents decline in thyroid function and arteriosclerosis, and reduces cholesterol content and lipid peroxide content in the brain. effective.

The results of the animal test regarding the aging delay of eggs according to the present invention are as follows:
It is as follows.

Example Two groups of SD rats were established with 18 rats per group.The rats in this experimental group were fed commercially available rat feed mixed with 1% iodine-rich egg powder obtained in the same manner as in Example 2. On the other hand, the rats in the control group were fed a mixture of commercially available rat feed with 1% ordinary egg powder added and raised separately. Eight rats were sacrificed after 7 months of rearing, and 10 rats were sacrificed after 19 months of rearing, and the cholesterol and lipid peroxide contents in the brain were measured. The results are shown in Table 1.
The eggs of the present invention were found to have an aging-delaying effect, such as a decrease in cholesterol and lipid peroxide content in the brain during aging.

Example Two groups of SD strain male and female rats were set up with 12 rats per group.The rats in this experimental group were fed with commercially available rat feed supplemented with 1% iodine-rich egg powder obtained in the same manner as in Example 2. On the other hand, rats in the control group were fed a mixture of commercially available rat feed and 1% normal egg grains. After 3 months and 17 months of rearing, the rats were fasted for 14 hours and exposed to cold at 2 ± 1°C for 24 hours, during which the rectal temperature,
73 and T1,000 in blood were measured over time. The measurement results are shown in Table 2, and there was no difference between the two groups in response to cold exposure at a young age (after 3 months).
Regarding the rats reared for 17 months, in the experimental group of the present invention, there was little decrease in body temperature, similar to young rats, and the level of blood T3 was maintained high after 24 hours, and anti-aging effects were observed.

Table 2 Example 1 Ten chickens aged 480 days were fed and raised with commercially available adult chicken feed to which 2% seaweed powder with an iodine content of 5916 ppm was added. From 7 days after feeding, an average of 8
Eggs with a high iodine content of 60 g/egg were obtained.

Example 2 Calcium iodate was added to a commercially available adult chicken feed to give an iodine content of 2500 ppm, and this feed was fed to 10 chickens 5 months after they started laying eggs and raised. The average amount of iodine in the eggs obtained above was 45,007 tg/
It was. 100 kg of these eggs were dried with a spray dryer to obtain 23 kg of egg grains with an iodine content of 361 mg/kg.

Example 3 Laying chickens were fed with a commercially available adult chicken feed supplemented with 40 ppm of sodium iodide and 1% seaweed powder with an iodine content of 5916□ j ppm. By feeding with this feed, eggs with a high iodine content were obtained. The average amount of iodine in eggs laid 10 days after feeding was 750 mg/piece.

patent applicant Hiki Haisan Kogyo Co., Ltd. Agent Patent Attorney Masaru 1) Mamoru 2

Claims (2)

[Claims] (1) Iodine 300. An egg having an anti-aging effect characterized by a high content of more than 100 g. (2) The egg according to claim 1, which is obtained by feeding one or both of an iodine compound and seaweed to egg-laying birds in excess of the normal iodine requirement.