JPS59100198A - Detergent composition - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a cleaning composition that satisfies essential requirements for a cleaning agent such as foaming properties and cleansing properties, while successfully reducing irritation to the skin significantly. be.

Traditionally, surfactants in shampoos include products for professionals such as those used in hair salons, as well as commercially available products.
Mainly, alkyl sulfate ester salts, polyoxyezalene alkyl sulfate Nisder salts, alkylbenzene sulfonates, α-olefin sulfonates, and the like have been widely used.

However, although shampoos containing these surfactants have excellent cleaning power, they are all known to be highly irritating to the skin, albeit to varying degrees, and are not recommended by barbers and beauticians. Professionals who often come into contact with shampoo are more likely to develop skin problems such as rough hands.

Also, recently, young people who have a particularly developed sense of fashion wash their hair more often, but even the general public washes their hair less than 3 to 3 times.
The number of people washing their hair every day has increased to four times a week, and if they continue to wash their hair with shampoos that contain strong irritating surfactants, they can cause problems such as rough scalp, leading to dandruff and itching. be.

From these points, the current situation is that there is a strong demand for the use of shampoos with low skin irritation, not only for professional use but also for general commercial use.

Focusing on the above points, Fuhatsu Kaione et al. have conducted intensive research on surfactants and surfactant compositions that have strong protein denaturing power, and have found that repeated use of these surfactants can cause severe roughness,
On the other hand, surfactants and shampoo compositions with low protein denaturing power can cause skin problems such as rough hands even after long-term use, and dandruff can also occur on the scalp. was found to be significantly reduced.

That is, for various surfactants and mixed surfactant compositions, we measured the protein denaturation rate, conducted rough hand tests using actual human hands, and measured the amount of dandruff caused by actual use (prolonged use). The inventors discovered that surfactants and mixed surfactant compositions with low levels of dryness tend to cause less rough hands and a tendency to reduce the amount of dandruff, leading to the completion of the invention of the present cleaning composition.

fill, the present invention has the general formula (A,)2R,0O-N-01(20H2SO,M...
・・・・・・・・・・・・・・・・・・(A, 1 (in the formula R
7 represents an alkyl or alkenyl group having an average number of carbon atoms of 7 to 9; M represents a lower alkyl group having an average of 1 to 3 carbon atoms; M represents an alkali metal or an organic amine. )
An alkyl alkyl taurine salt type anionic surfactant represented by the general formula (13) % formula % () (in the formula, R3 is an alkyl group or an alkenyl group having an average number of carbon atoms of 8 to 2, R4 and R1 is an average carbon atom, a lower alkyl group having 1 to 3, or -OH,, CH20
Represents H group, -CH,, CH, OH□OH group. ) represented by ~amine''-1-cyto-type co-1' polarity! +'1l
il activator, (hereinafter referred to as Kanayama) (in the formula, R6 represents a γ-alk group or an alkenyl group having an average number of carbon atoms of 7 to 19, m and n are integers, and m
+n is engineering or 5. It is. The present invention provides a detergent composition containing an alkylolamide type nonionic surfactant represented by the following formula as all active ingredients.

The preferred blending ratio of the active ingredients is such that the weight ratio of (A) and (B) is 91 to 12, and - (A) + CB): (o
) weight ratio is in the range of 15゛1 to ]:1, and (A
) + (B)→-(0) is the ratio of IO to 50 parts by weight of the total.

Although the Argiloy M phosphate type anionic surfactant represented by the general formula (A) has sufficient W surface activity such as foaming and detergency, it has a strong protein denaturing ability and cannot be used alone. If it is, the desired mild detergent cannot be obtained. On the other hand, amine oxide type represented by the above general formula (E)
Semi-polar surfactants have low protein denaturation properties and are weakly irritating, but their surfactant properties such as foaming and detergent properties are inferior, so when used alone, they have unsatisfactory performance. The disadvantage is that it is not possible to obtain a cleaning agent with

The present inventors have discovered an alkylclarine salt type anionic surfactant represented by the general formula (A) and an alkylclarine salt type anionic surfactant represented by the general formula (A).
When the amine surfactants represented by B) are mixed at a certain ratio, phenomena such as an increase in viscosity and a decrease in critical micelle concentration will occur compared to when each agent is used alone. discovered that it was formed by a complex of an anionic surfactant and an amphoteric surfactant.
In this mixture at a constant ratio of -, the surfactant ability such as foaming property and detergency is superior to that of the argyloyl alkyl taurine salt type anionic, 4-monosurfactant represented by the formula -e (Al) alone. At the same time, the protein denaturation ability is expressed by the general formula (
B)
It was discovered that the oxidation rate was significantly reduced to a level that was at least as good as that of the case of the semi-transparent type semi-Mh surfactant. Immediately, by mixing to form a complex, a synergistic effect was clearly exhibited, and a hypoallergenic surfactant composition with low protein denaturation ability while maintaining excellent surfactant ability was successfully obtained. This is what I did.

The weight ratio of (A):(B) is 91 to],
The range is 2. Mixing ratios outside this range or other Ani-A
If a large amount of a surfactant or the like is added to disrupt the balance of the system, a sufficient effect of lowering protein denaturation performance cannot be obtained.

In addition, the alkylolamide type nonionic surfactant represented by the general formula (C) used in the present invention has been used in anionic surfactant shampoos to have a foaming enhancement effect and a thickening effect. is blended for the purpose of improving low-temperature stability (reducing Kraft point), etc., but in the present invention, oral (
It was found that by blending 0) in a certain ratio, the protein denaturation ability was further reduced. The preferred ratio of (A) (-(B) '(0) is 1 by weight)
It is in the range of 5:1 to 1:1, and from this ratio (A)
If there is too much -1-(B), the protein denaturation property reducing effect of (C) will not be sufficiently exhibited, and if there is too much (0), the detergency and foaming properties of the shampoo will be impaired.

Further, (A) + (13) 10 (0) is preferably 10 to 50 parts by weight of the total to form a liquid shampoo.

In the present invention, the alkyloylalgyl taurine salt type anion interface represented by the general formula (A)? The M i agent is, for example, a fluo,yl group R,00-(, CI 1
'2300- ,C,H,,7co-1C,,H,,
Co −,0,, R3,0O-5CI7H330+il
, -, C8 to 3] mixed alkyl group -4 obtained from coconut oil fatty acid is CI(3-1(!, 11.-1C3I(? 'l') as the alkyl group R2.
But, as counter-sign M, -Li, -K, -tl
Examples include a, 1,000/1/-A amine, amine, and triethanolamine.

Iswa 98 (B) ” f < h Q Asru Amin λ Soran cliff book is -i+, Western movie n Zun no Rumushi II tJ 1
5'Jt+t゛a11, V14 R3) knee ttt, i
Cr1H+5-, CQHI9- jC,,) (Two 3- I CIqHλυ, CIS?13+
I C pull T) (33-, C four to four three sounds C1 wa Hλ9-
2 Towards the end, there are seven beasts, and they are aiming for the end of the world.
\Suqo Ren 7? a), gi+4 1 ht' e,+,
B-j& diagram (x(1(+-13.

~C) -15+-C31(wa, -C60 days, -0(
□Cl-1zO day.

-5O Tsui C Tsui CJ () -0H strenuously raises and swims.

(The following is a blank space) The alkylolamide type nonionic surfactant represented by the general formula (0) is, for example, an alkylolamide-type nonionic surfactant having an alkyl/f group R, co-
As, Col+23co+CIq"ztc
O-IC1! 'ju co+c, □l+, 5(!0-.
(!,,11.,00-, coconut oil fatty acid is 8 to 6 carbon atoms) and the like.

The detergent composition of the present invention has a desired c1-to-tJ, a part commonly added to a detergent, for example, a high... Aj”le ml
, -ru, phosphorus derivatives, protein derivatives, and fatty acid esters of polyethylene chloride -7+-.
b n component, propylene glycol A1 glycerin,
Boriejire> Ri! Moisturizing agent ingredients such as J. ), sequestrants, preservatives, bactericidal agents, PL+ regulators, ultraviolet absorbers, antioxidants, pigments, fragrances, and the like.

Next, the present invention will be explained in detail with reference to Examples, but the present invention is not limited thereto.

Prior to the examples, the test methods and evaluation methods employed in each example will be explained.

Foaming test method C aC Og 70 ppm In hard water, prepare 4 ooml solution of sample concentration z% and measure the amount of foaming using a cylindrical syringe with a stirrer at a temperature of 40°C. did.

0. Good foaming Foam volume: 1 or more zoom △... Normal foaming Foam volume: x, 5oomj or more 2. ooooo
m/! Less than ×...foam\γchi defective ith amount 1,5
Less than oomj Cleanability Test Method C a O,,,/'M g O- 3. ,/'l,5
A solution with a sample concentration of 1% was prepared using DH artificial hard water7, and the artificial sebum-contaminated cloth was washed using wool surge.

At a temperature of 40°C, turn on the turbotometer (J
It was cleaned using TsK-3370, and the cleaning efficiency was determined from the reflectance before and after cleaning.

Ro - Rs Ro Reflectance of original cloth (wool serge) RB: Reflectance of contaminated cloth Rw Reflectance of contaminated cloth after washing O... Good cleaning performance Cleaning efficiency 80% or more Δ...
・Cleanability: Average cleaning efficiency: 60% or more. 1 so
Less than % ×...poor cleaning performance Washing efficiency less than 60% Protein denaturation rate measurement method When a sample is added to an ovalbumin pi-1 7 buffer solution at a sample concentration of 1% using aqueous high performance liquid chromatography. The ovalbumin denaturation rate of 220
Denaturation rate measured using the n-island yield peak) - -
x 1o.

H○ ■(0 Height of the 220 nm absorption peak of ovalbumin Hs: Height of the 220 nm absorption peak when a sample is added to the ovalbumin buffer solution.

◎... Ovalbumin denaturation rate less than 30% O... Ovalbumin denaturation rate 1 to less than 60% Δ... Ovalbumin denaturation rate 60% or more but less than 80% ×... Ovalbumin denaturation rate 80% Above rough hand test method For each sample, a panel of 10 people in total, 5 men and 5 men, was used, and the left or right hand was tested at a sample concentration of 5% and a temperature of 35%.
°C in an aqueous solution and the other hand in water at the same temperature for 10 minutes twice a day for 20 consecutive days,
The difference between the rough skin conditions on the left and right sides was determined with the naked eye.
.

◎...by rough hands 1. ＋'<Weak 0-1 out of 10 people Roughness was observed on the sample side ○...Slightly roughness in hands 2-4 out of 10 people Roughness was observed on the sample side △
... Roughness slightly strong 5-7 out of 10 Roughness was observed on the sample side × Roughness of hands I-1 < Strong
8 to 10 out of 10 people Dandruff generation amount measurement method using rough hands on the sample side Usually, lauryl edelsulf, general commercially available shampoo (contains no drug for dandruff itching)
Using the sample, the hair was washed 5 times using a towel using the same washing frequency and method as usual, and the amount of dandruff before and after using the sample was compared. The amount of dandruff for 3 days after washing the hair with a commercially available shampoo and the amount of dandruff for 3 s tl from the last day of washing the hair 5 times using the sample were measured.

Dandruff is collected by suctioning 1 inch from the head using a suction device with an N1 cloth, and in order to eliminate errors caused by other foreign substances, the amount of nitrogen is determined using the Kera 1-ball method, and this is measured at 6.25 (ff L). The average protein amount was determined and defined as dandruff 1 (m9·' head).

The number of panels was 3 for each sample, and the comparison was made using the average value.
Less than △・The amount of dandruff after using the sample is O
% or more L Less than 10% Decreased ×・--Increased amount of dandruff after using the sample (side, lower gold White Examples 1 to 8) Prepare a shampoo consisting of the following Table 1 + the composition described here, Its foaming properties, cleaning properties, protein denaturation rate, roughness on hands, and amount of dandruff were investigated.

These results are shown in Table 1 (Example) and Table 2 (Comparative Example)
+J is shown.

Table 1 Table 2 (Unit: weight %) - - As described above, the examples of the present invention have excellent foaming properties, cleaning properties, protein denaturation rate, rough carability, and ◇Example 9 A shampoo consisting of the following formulation was prepared.

:1-ffylmethyltaurine-Na,
lo (heavy Jft%) lauryl dimethylamine] Kid 6 Yang fatty acid di-alamide 4 Geliceri 2
Anzu sashimi
03 Wednesday
Remaining All Examples] 0 A shampoo with the following composition was prepared...-7 Carp) v Meni-Lutaurin-Na, 1
0 (jlj amount %) Ui'7 Ryldi I-f Ruminogindo 6-Yang fatty acid dichotanolamide 4 Polyethylene glycol: 1-l 2 Citric acid
02 cationized cellulose Sue-1-7
-Le 0.6 fragrance
03 Wednesday
Remaining Example n A shampoo consisting of the following composition was prepared...Ch% l-N glycol fatty acid ester 2
(Weight%) Lauroyl methyl taurine-Na
10 Cocoylethylamine A
Oxide 6-lauric acid diethanolamide
4poly (Jimeirujirirua)・
mocoichium chloride) 1 citric acid 02 fragrance
fee
α3 Water Remaining patent applicant Shiseido Co., Ltd. Procedural amendment (voluntary) 1. Indication of the case Patent Application No. 210012 of 1982 2. Name of the invention Cleaning composition 3. Person making the amendment) 4. Amendment Subject Specification 5, Contents of Amendment (1) The scope of claims in the specification will be amended as shown in the attached sheet.

(2) 1% in the 8th line from the bottom of page 8 of the specification, where it says “division”
” and correct it.

(3) "%" in the description, page 11, line 1, copy 1"
First, I corrected it.

(Margin below) (Attachment) 2. Claims (1) General formula (Δ) Z R, C0NCII2CIl, SO3M ------(A
) (in the formula, R is an alkyl group or an alkenyl group having an average of 7 to 19 carbon atoms, R2 is a lower alkyl group having an average of 1 to 3 carbon atoms, and M represents an alkali or an organic amine (6). An alkyl-ylalkyl taurine salt type anionic surfactant represented by the formula (I3) 1? + R3-7-)O----1(B) 5 (wherein R3 is an alkyl group or alkenyl group having an average number of carbon atoms of 8 to 2o, R+ and R5 are an average number of carbon atoms of 1
Represents the lower alkyl group of Noru 3, -C112CIl□OH group or -C112C112CI+2011 group.

), and an amine oxide type semipolar surfactant represented by the general formula (C) (wherein Rc represents an alkyl group or alkenyl group having an average number of carbon atoms of 7 to 19, and apex, ↓, and n are integers. m
-4-n is 1 to 5. ) A detergent composition containing an alkylolamide type nonionic surfactant represented by the following as an active ingredient.

(2) The weight ratio of the alkyl alkyl taurine salt type anionic surfactant represented by the general formula (A) to the amine oxide type semipolar surfactant represented by the general formula (B) is 9
:l to 1:2, and the weight ratio of (A) 4-(B) to the alkylolamide type nonionic surfactant represented by the general formula (C) is in the range of 15:1 to 1:1. and (A) + (B) + (C) is 10 to 5 of the total
The cleaning composition according to claim (1), which contains 0% by weight.

72

Claims (2)

[Claims] (1) ・General formula (A)
The low-class guy 1. 1μ, M is alkali (1〉ka or organic amine) -C'! <Wasareru-I゛ru 11Jylal general formula (]3)% formula%() ((in the formula ■(3 is an average number of carbon atoms of 8 or 1)
group or a/1kenyl group, R4 and R, are lower argyl groups having an average number of carbon atoms of 1 to 3 or -OH20H20
Represents H group, -OH20H20H20H group. ) Aminemexide type, semi-polar surfactant, (hereinafter blank) General formula (0) where m+n is ] to 5. ) A cleaning composition containing as an active ingredient an argyrolamide type nonionic surfactant. (2) - Alkyloylargyl urinate type anionic surfactant represented by general formula (A) and - general formula (B)
(A)
The cleaning composition according to claim 1, wherein the proportion is +(B) part. (Margin below)