JPS5842189B2 - 7,8− ハロチカン −1,2,3,4− テトラヒドロイソキノリンカゴウブツノ セイホウ - Google Patents

7,8− ハロチカン −1,2,3,4− テトラヒドロイソキノリンカゴウブツノ セイホウ

Info

Publication number
JPS5842189B2
JPS5842189B2 JP50015229A JP1522975A JPS5842189B2 JP S5842189 B2 JPS5842189 B2 JP S5842189B2 JP 50015229 A JP50015229 A JP 50015229A JP 1522975 A JP1522975 A JP 1522975A JP S5842189 B2 JPS5842189 B2 JP S5842189B2
Authority
JP
Japan
Prior art keywords
formula
tetrahydroisoquinoline
same
substituted
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP50015229A
Other languages
English (en)
Japanese (ja)
Other versions
JPS50108274A (US06580902-20030617-M00005.png
Inventor
カイザー カール
グラブ ペンドルトン ロバート
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of JPS50108274A publication Critical patent/JPS50108274A/ja
Publication of JPS5842189B2 publication Critical patent/JPS5842189B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
JP50015229A 1974-02-08 1975-02-04 7,8− ハロチカン −1,2,3,4− テトラヒドロイソキノリンカゴウブツノ セイホウ Expired JPS5842189B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/440,925 US3939164A (en) 1974-02-08 1974-02-08 7 AND 8-Halo substituted 1,2,3,4-tetrahydroisoquinoline compounds

Publications (2)

Publication Number Publication Date
JPS50108274A JPS50108274A (US06580902-20030617-M00005.png) 1975-08-26
JPS5842189B2 true JPS5842189B2 (ja) 1983-09-17

Family

ID=23750761

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50015229A Expired JPS5842189B2 (ja) 1974-02-08 1975-02-04 7,8− ハロチカン −1,2,3,4− テトラヒドロイソキノリンカゴウブツノ セイホウ

Country Status (13)

Country Link
US (1) US3939164A (US06580902-20030617-M00005.png)
JP (1) JPS5842189B2 (US06580902-20030617-M00005.png)
BE (1) BE824924A (US06580902-20030617-M00005.png)
CA (1) CA1052793A (US06580902-20030617-M00005.png)
DE (1) DE2505005A1 (US06580902-20030617-M00005.png)
FR (1) FR2260351B1 (US06580902-20030617-M00005.png)
GB (1) GB1441378A (US06580902-20030617-M00005.png)
HK (1) HK22880A (US06580902-20030617-M00005.png)
HU (1) HU168562B (US06580902-20030617-M00005.png)
IE (1) IE40594B1 (US06580902-20030617-M00005.png)
IL (1) IL46409A (US06580902-20030617-M00005.png)
NL (1) NL7501482A (US06580902-20030617-M00005.png)
ZA (1) ZA7563B (US06580902-20030617-M00005.png)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200754A (en) * 1979-02-02 1980-04-29 Smithkline Corporation Method for preparing 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline
ZA802987B (en) * 1979-07-02 1981-05-27 Smithkline Corp Thiadiazolo- and oxadiazolotetrahy droisoquinoline compounds
US4258049A (en) * 1979-07-02 1981-03-24 Smithkline Corporation Inhibiting phenylethanolamine N-methyltransferase with thiadiazolo and oxadiazolotetrahydroisoquinolines
US4228170A (en) * 1979-08-30 1980-10-14 Smithkline Corporation 7- and/or 8-Sulfur substituted 1,2,3,4-tetrahydroisoquinoline compounds
US4868304A (en) * 1988-05-27 1989-09-19 Iowa State University Research Foundation, Inc. Synthesis of nitrogen heterocycles

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3314963A (en) * 1962-07-23 1967-04-18 Pfizer & Co C Azabenzocycloalkane-n-carboxamidines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2998422A (en) * 1953-03-25 1961-08-29 Irwin Neisler And Company Bis-(nu-heterocarbocyclic) alkanes
US2785166A (en) * 1954-10-25 1957-03-12 Searle & Co Ethers of heterocyclic alcohols and tetrahydroisoquinolinealkanols, their salts and methods for their production
US2876223A (en) * 1957-02-20 1959-03-03 Pfizer & Co C Synthesis of substituted 1, 3 diazacyclopentenes and 1, 3 diazacyclohexenes
NL261409A (US06580902-20030617-M00005.png) * 1960-02-19

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3314963A (en) * 1962-07-23 1967-04-18 Pfizer & Co C Azabenzocycloalkane-n-carboxamidines

Also Published As

Publication number Publication date
CA1052793A (en) 1979-04-17
FR2260351B1 (US06580902-20030617-M00005.png) 1978-07-21
BE824924A (fr) 1975-07-29
IL46409A (en) 1978-04-30
NL7501482A (nl) 1975-08-12
FR2260351A1 (US06580902-20030617-M00005.png) 1975-09-05
GB1441378A (en) 1976-06-30
US3939164A (en) 1976-02-17
IL46409A0 (en) 1975-04-25
HU168562B (US06580902-20030617-M00005.png) 1976-05-28
IE40594B1 (en) 1979-07-04
ZA7563B (en) 1976-01-28
AU7721475A (en) 1976-07-15
JPS50108274A (US06580902-20030617-M00005.png) 1975-08-26
IE40594L (en) 1975-08-08
HK22880A (en) 1980-05-09
DE2505005A1 (de) 1975-08-14

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