JPS58198403A - Insect repellent composition - Google Patents

Abstract

PURPOSE:An insect repellent composition, prepared by incorporating a specific amount of a specific amine oxide with N,N-diethyltoluamide, and solubilizing the N,N-diethyltoluamide without incorporating ethanol, usable in horses for races, and having a higher lasting effect than the composition containing the ethanol. CONSTITUTION:An insect repellent composition prepared by incorporating (a) 5-25wt% N,N-diethyltoluamide, e.g. N,N-diethyl-m-toluamide, with (b) 4-20wt% compound of the formula (R is 8-22C alkyl or alkenyl; R<1> and R<2> are CH3, C2H5, C2H4OH or C3H6OH; m is 1 or 2; n is 0 or 1) and (c) 50-90wt% water, and preferably further (d) 20wt% or less another surfactant, e.g. a cationic or ampholytic surfactant having the germicidal activity or a nonionic surfactant capable of assisting the solubilization of the component (a). The composition containing no ethanol is usable in horses for races just before the races in which the use of the ethanol is prohibited.

Description

DETAILED DESCRIPTION OF THE INVENTION This invention relates to an insect repellent composition containing N,N-diethyltoluamide.

From pests such as mosquitoes, gadflies, biting flies, and gnats, to people and animals, etc.
N,N-diethyltoluamide is used as an insect repellent to protect the skin. Since this N,N-diethyltoluamide is insoluble in water, it is added to a 20-50 diethanol aqueous solution.
It is generally used after being dissolved at a concentration of 5 to 15%.

However, although there are no particular problems with such insect repellent compositions when used on humans, in cases where the use of ethanol is prohibited, such as on racehorses, it is recommended that they be used immediately before a race. Therefore, there has been a desire to develop an insect repellent composition that can be used even just before a race.

This invention was made in response to such a demand, and by blending a specific amine oxide, N can be produced without using ethanol.

The object of the present invention is to provide an insect repellent composition that can dissolve N-diethyltoluamide and has a long-lasting effect.

This invention relates to N,N-diethyltoluamide 5-251 (wherein, R is an alkyl group or alkenyl group having 8 to 22 carbon atoms, Bl and W are methyl group, ethyl group, hydroxyethyl group, or hydroxypropyl group, m is 1 or 2, and n is 0 or 1.) As the N,N-diethyltoluamide, N,N-diethyl-m-)ylamide can be used.

In the above general formula (1), the number of carbon atoms represented by R is 8 to
As the alkyl group or alkenyl group of 22, octyl group, 2-ethylhexyl group, nonyl group, decyl group, undecyl group, lauryl group, tridecyl group, myristyl group, palmityl group, stearyl group, isostearyl group, oleyl group, linole Examples thereof include behenyl groups, behenyl groups, etc., and these may be one type or several types, or groups derived from natural products containing a plurality of these groups, such as a coconut alkyl group.

The insect repellent of the present invention comprises N,N-diethyl)/reamide,
It is produced by mixing the amine oxide of general formula +1) and water in the above proportions. The blending ratio of N,N-diethyltoluamide is preferably 10 to 20% by weight. The order of the above mixing is not particularly limited and may be mixed in any order.

When N-diethyltoluamide is solubilized with amine oxide alone, it is desirable to solubilize 100 parts by weight of N,N-diethyltoluamide with 75 to 110 parts by weight of amine oxide. Also, the temperature during mixing is not particularly limited, but N
, 60°C because N-diethyltoluamide is volatile.
It is preferable to mix the following:

In the present invention, the blending ratio of N,N-diethyltoluamide is limited because if it is less than 5% by weight, there will be no sustained effect, and if it exceeds 25% by weight, it is necessary to increase the blending ratio of amine oxide. This is because the viscosity of the composition increases significantly, making it impossible to spray. The reason why the blending ratio of amine oxide is limited is that if it is less than 4% by weight, #,N-diethyltoluamide cannot be dissolved even if other surfactants are used together, and the composition becomes cloudy. This is because the composition will separate over time, and if it exceeds 20% by weight, the viscosity of the composition will increase significantly, making it impossible to spray.

The insect repellent composition of the present invention may be used as it is as formulated as described above, but may further contain 20% by weight or less of other surfactants.

Examples of the surfactant include cationic surfactants such as alkyldimethylbenzylammonium chloride and alkyltrimethylammonium chloride, and amphoteric surfactants such as alkylbetaine, which impart bactericidal properties to the composition; - Nonionic surfactants such as polyoxyethylene alkyl ether and polyoxyethylene alkylaryl ether are used to assist in solubilizing diethyl metatoluamide. In addition, it is also possible to blend other components within a range that does not impair the effects of the present invention.

The insect repellent composition obtained in the above manner protects the skin from pests such as mosquitoes, gadflies, bites, and gnats by directly applying it to the skin of animals or animals, or by applying it by means such as spraying. be able to.

As explained above, according to the present invention, since a specific amine oxide is blended into the insect repellent composition, N,N-diethyltoluamide can be solubilized without blending ethanol, which makes it possible to compete with It can also be used on horses, and it has a longer lasting effect than those made solubilized with ethanol.

Next, examples of the present invention will be described.

Example 1 N,N-diethyl-m-)ylamide iog, 10 g of the surfactant shown in Table 1, and 80 g of water were mixed,
- The solubility of diethyl-m-toluamide was examined by visual observation. The results are shown in Table 1.

“In Table 1, the number appended to polyoxyethylene indicates the average number of moles of ethylene oxide added.

The results in Table 1 show that N,N-diethyl-m-toluamide can be solubilized by blending amine oxide within the above range.

Example 2 120 g of N,N-diethyl/l/-m-toluamide, 35% aqueous solution of dimethyl diurylamine oxide 2
40,9. and 10.9% of a 40% by weight aqueous solution of coconut alkyldimethylbenzyl ammonium chloride,
Next, 630 g of water was added to obtain a uniform and transparent insect repellent composition.

When this composition was left for one month at 0° C. and 50° C., no changes over time such as clouding, separation, or coloring were observed, and it was stable. In addition, for 10 people, about 50% of the above composition was administered.
ml sprayed and measured the duration of the effect, 1
Lasted 0-12 hours. For comparison, approximately 5 ml of a composition prepared by dissolving 12 g of N,N-diethyl-m-toluamide in a 35 weight percent aqueous solution of ethanol 8811 was sprayed in the same manner, and the duration of the effect was measured. Met.

From the above results, it can be seen that the insect repellent composition of the present invention does not change over time, is stable, and has a longer lasting effect than one dissolved in ethanol.

Agent Patent Attorney Sei Yanagi Hara

Claims (1)

[Claims] fl+#, #-n ethertoluamide 5 to 25 times @qb,
Amine oxides 4 to 20 represented by the following general formula il+
Insect repellent composition 3, IR[(OCH,CH,)mOCH,CH,), -N→
O・-Ill2 (wherein, R is an alkyl group or alkenyl group having 8 to 22 carbon atoms, R1 and R2 are a methyl group, ether group, hydroxyether group, or hydroxypropyl group, m is 1 or 2, and n is The insect repellent composition according to claim 1, further comprising 12120% by weight or less of another surfactant, which is 0 or 1. (3) The other surfactant is a cationic or amphoteric surfactant having bactericidal properties, or a nonionic surfactant that assists in solubilizing Fi#, N-diethyltoluamide. The insect repellent composition according to item 1 or 2. (4) The insect repellent composition according to any one of claims 1 to 3, wherein #, #-diethyltoluamide is N,N-dixthyl-m-toluamide.