JPS58194805A - Cosmetic - Google Patents

Abstract

PURPOSE:To provide a clear lotion which does not cause gelation under any pH condition, keeps its transparency and stability even after long-term storage, and has high safety to the skin, by compounding an oily substance with water using a glycyrrhizic acid salt as a solubilizing agent in combination with urea. CONSTITUTION:The objective clear lotion is prepared by compounding (A) one or more oily substances selected from flavor, animal or vegetable oil, hydrocarbon, synthetic ester oil, higher fatty acid, higher alcohol, oil-soluble hormone, oil-soluble vitamin, and oil-soluble pigment, (B) water, (C) glycyrrhizic acid salt composed of alkali metal salt of glycyrrhizic acid, ammonium salt of glycyrrhizic acid and basic amino acid salt of glycyrrhizic acid, and (D) urea. The amount of the salt is 0.1-10wt% based on the cosmetic, and that of the urea is >=10wt% based on the glycyrrhizic acid salt and 0.01-20wt% based on the cosmetic. It is suitable as an emollient lotion, astringent lotion, after-shave lotion, hair tonic, and water-based makeup base.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to clear lotions. More specifically, the present invention relates to a transparent lotion that is highly safe for the skin, has excellent texture and fluidity, and has an oily substance that is transparently solubilized in an aqueous system by blending glycyrrhizinate and urea.

In order to solubilize oily substances such as fragrances, oil-soluble hormones, and synthetic ester oils into aqueous systems, it is common to use surfactants such as ethylene oxide adducts of higher alcohols. . However, surfactants
It may irritate the skin and eyes, especially sensitive skin,
Not recommended for use on rough, sunburned, or acne-prone skin.

Conventionally, as a transparent lotion that does not use surfactants,
JP-A-52-151'736 discloses a dipotassium glycyrrhizinate as a solubilizer. However, due to its nature, dipotassium glycyrrhizinate gels significantly in an acidic region and has the disadvantage of decreasing solubility and becoming cloudy.
Low-sihun that has a gentle effect on skin close to 5, and also p
It is not possible to produce astringent lawn yong with low H, and the pH is 6.1.
Applications to the above-mentioned solubilized lotions are limited.

The present inventors have conducted intensive research to obtain a transparent lotion that overcomes the above-mentioned drawbacks, and have found that when urea is blended with glycyrrhizinate, gelation occurs in any acidic region below ρ11, especially 6]. The present inventors have discovered that they can not only prevent this from occurring, but also significantly improve the solubility of glycyrrhizinate and enhance its solubilization ability, leading to the completion of the present invention.

That is, the present invention relates to transparent rho salts, glycyrrhizic acid ammonium salts, and mono-, di-, and tri-salts of glycyrrhizic acid basic amino acid salts, which are characterized by containing glycyrrhizinate, urea, an oily substance, and water, such as , monosodium glycyrrhizinate monoammonium ruritinate salt, disodium glycyrrhizinate salt, potassium gelycyrrhizate salt, trina I/rium glycyrrhizate salt,
These include glycyrrhizic acid mono-L-arginine salt, glycyrrhizic acid mono-L-lysine salt, glycyrrhizic acid di-L-arginine salt, glycyrrhizic acid di-L-lysine salt, and the like.

These have excellent effects on the skin, such as anti-inflammatory effects and anti-allergy effects caused by fragrances, and are not irritating to the skin and eyes, unlike the surfactants mentioned above. The amount of glycyrrhizinate is 01~]O
Weight%. If it is less than 0.01% by weight, the solubilization of oily substances is not sufficient and it becomes cloudy, and if it is more than 10% by weight, it becomes sticky and feels bad when used.

Urea used in the present invention is one of the main components of NMF (natural moisturizing factor), and has excellent effects on the skin such as urea's ability to retain moisture in the stratum corneum, wound healing effect, and bactericidal effect. Contains urea for glycyrrhizinate
It is less than 0% by weight. ] If the content of ○ is less than % by weight, gelation cannot be prevented in an acidic region, particularly at a pH of 6.1 or lower. In addition, the cosmetics contain 00] to
% by weight. If it is more than the weighted amount %, it will be sticky and the feeling of use will be poor. 11 Oily substances used in the present invention include natural and synthetic fragrances commonly used in transparent lotions, animal and vegetable oils such as olive oil, jojoba oil, and castor oil, isopropyl myristate,
Cetyl isooctanony!・Etc. (D Synthetic fQ ester oil, oleyl alcohol, higher alcohols such as octyldodecanol, higher fatty acids such as secondary leic acid and isostearic acid, hydrocarbons such as liquid paraffin and squalane, estradiol, ethinyl estradiol, diethylstilbestrol, etc. oil-soluble hormones, oil-soluble vitamins such as vitamin A palmitate, vitamin E acetate,
Tadan ■, Quinizarin Green SS1 Tetrapro A”T
"/y Oil-soluble pigments such as olein, etc. are included, and one or more of these are blended. The blending amount is 1% by weight or less, an amount that can bring about the effect of adding the oil-based substance. If the amount is more than % by weight, it becomes difficult to solubilize, resulting in cloudiness.

The amount of water used in the present invention is usually about 99.8% by weight.

The transparent lotion of the present invention may contain alcohol, a humectant, a preservative, and the like, if necessary.

The transparent lotion of the present invention can be applied to any pll (especially 61
It does not gel even in the following acidic regions, maintains transparency and stability even after long-term storage, is highly safe for the skin, and has excellent effects on the skin. It is suitable for use as an astringent lotion, aftershave lotion, hair makeup, water-based makeup, and makeup.

(The following is a blank space) Next, examples of the present invention will be shown. The present invention is not limited thereby. The blending amount is % O [Example-1 Astringent Lotion Comparative Examples-1, 2] (Production method) Dissolve ■, ■, ■, ■, ■ in ■, and add ■, ■ to ■.
A clear astringent lotion was obtained by adding the solution.

Comparative Examples-1 and 2 were also obtained in the same manner.

As is clear from the characteristics shown in the table, Example-1 has good transparency, condition, and astringent effect, whereas Comparative Example-1 has an astringent effect but is gelatinized and cloudy, and compared to Example-2 has good transparency and condition, but lacks astringent effect.Example-1 has high skin safety, good transparency, and astringent condition that could not be obtained with conventional technology. Makeup 1 TJso, Wa, Bottom margin) [Example-2 Soft lotion Comparative example-3] (Manufacturing method) After dissolving ■ in a part of ■, add ■ and stir and mix. Add ■ to this and dissolve it, then add ■ to solubilize it.

To this, a solution of ■ and ■ was added to the remaining part of ■ to obtain a softening lotion.

Comparative Example 3 was also obtained by the same manufacturing method.

As is clear from the characteristics shown in the table, Example 2 has good transparency and condition, while Comparative Example 3 has poor solubility of monoammonium glycyrrhizinate and is cloudy and gelatinous. Therefore, Example-2 is a softening lotion that has high skin safety, transparency, and a mild effect on skin that is in good condition, which could not be obtained using conventional techniques.

[Example-3 to 6 Medicinal lotion Comparative example-45] ■■
, ■, ■, and ■ were dissolved, and a solution of ■, ■, and ■ dissolved in ■ was added to this to obtain a transparent medicated lotion.

As is clear from the table, if the blending amount of urea is 0% by weight or more based on glycyrrhizinate, the transparency and condition are good, whereas if it is less than 10% by weight, the transparency and gelation are poor. cause a change.

Also, if the blended amount of urea is greater than the weighted amount%! It becomes stiff and feels uncomfortable when used.

Example 3.4.5.6 is a medicinal example 1 example-7 that has high skin safety and has a mild effect on the skin with good transparency and condition.
8,9 Aftershave Lotion Comparative Examples-6,7] (Manufacturing method) A transparent aftershave lotion was obtained in the same manner as in Example-1.

As is clear from the table, glycyrrhizinate is 01-1
At 0% by weight, the transparency, condition, and feeling in use are good, whereas at less than 01% by weight, turbidity occurs, and when it exceeds 00% by weight, it becomes sticky and feels bad in use.

(Margin below) (Manufacturing method) A transparent hair tonic was obtained in the same manner as in Example-1.

This hair tonic had a pH of 4.6 and was transparent and in good condition.

Claims (3)

[Claims] (1) Transparent lawn jellyfish characterized by containing glycyrrhizinate, urea, oily substance and water (2) Glycyrrhizinate l Glycyrrhizic acid alkali metal salt, glycyrrhizic acid ammonium salt, glycyrrhizic acid basic amino acid salt Claim 1
Transparent lotion as described in section. (3) The oily substance is one or more of the following: fragrances, animal and vegetable oils, hydrocarbons, synthetic ester oils, higher fatty acids, higher alcohols, oil-soluble hormones, oil-soluble vitamins, and oil-soluble pigments. The transparent lotion described in item 1.