JPS5798300A - Manufacture of pregnane derivative - Google Patents

Manufacture of pregnane derivative

Info

Publication number
JPS5798300A
JPS5798300A JP56167986A JP16798681A JPS5798300A JP S5798300 A JPS5798300 A JP S5798300A JP 56167986 A JP56167986 A JP 56167986A JP 16798681 A JP16798681 A JP 16798681A JP S5798300 A JPS5798300 A JP S5798300A
Authority
JP
Japan
Prior art keywords
intermediates
manufacture
dihydroxycholecalciferol
metabolites
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56167986A
Other languages
English (en)
Other versions
JPH021160B2 (ja
Inventor
Deii Patsuchiyo Andoriyuu
Ii Baagaa Jiyunia Donarudo
Aaru Usukokobiku Miran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPS5798300A publication Critical patent/JPS5798300A/ja
Publication of JPH021160B2 publication Critical patent/JPH021160B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP56167986A 1980-10-22 1981-10-22 Manufacture of pregnane derivative Granted JPS5798300A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/199,167 US4310467A (en) 1980-10-22 1980-10-22 Process and intermediates for the synthesis of vitamin D3 metabolites

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP1143179A Division JPH0228194A (ja) 1980-10-22 1989-06-07 プレグナン誘導体

Publications (2)

Publication Number Publication Date
JPS5798300A true JPS5798300A (en) 1982-06-18
JPH021160B2 JPH021160B2 (ja) 1990-01-10

Family

ID=22736501

Family Applications (3)

Application Number Title Priority Date Filing Date
JP56167986A Granted JPS5798300A (en) 1980-10-22 1981-10-22 Manufacture of pregnane derivative
JP1143179A Granted JPH0228194A (ja) 1980-10-22 1989-06-07 プレグナン誘導体
JP3356520A Expired - Lifetime JPH0660195B2 (ja) 1980-10-22 1991-12-25 プレグナン誘導体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP1143179A Granted JPH0228194A (ja) 1980-10-22 1989-06-07 プレグナン誘導体
JP3356520A Expired - Lifetime JPH0660195B2 (ja) 1980-10-22 1991-12-25 プレグナン誘導体

Country Status (5)

Country Link
US (1) US4310467A (ja)
EP (1) EP0050325B1 (ja)
JP (3) JPS5798300A (ja)
AT (1) ATE14317T1 (ja)
DE (1) DE3171414D1 (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5112998A (en) * 1987-03-30 1992-05-12 Kuraray Co., Ltd. Pregnane derivatives and processes for production thereof
DE3854089T2 (de) * 1988-07-05 1995-11-02 Kuraray Co Steroid-verbindungen.
US5366736A (en) * 1989-02-16 1994-11-22 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
WO1990009179A1 (en) * 1989-02-16 1990-08-23 University Of Georgia Research Foundation, Inc. Treatment of tibial dyschondroplasia
US5316770A (en) * 1989-02-16 1994-05-31 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US7632518B2 (en) * 2002-01-15 2009-12-15 Dsm Ip Assets B.V. 25-hydroxy vitamin D3 compositions
US20080318870A1 (en) 2007-06-19 2008-12-25 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
US8242294B2 (en) 2007-06-19 2012-08-14 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
JOP20180077A1 (ar) 2007-06-19 2019-01-30 Kythera Biopharmaceuticals Inc تركيبات وطرق لحمض صفراوي تخليقي
CN102511369A (zh) * 2011-10-27 2012-06-27 山东省农业科学院蔬菜研究所 免维护花盆
CN108383767B (zh) 2018-02-06 2020-03-24 山东海能生物工程有限公司 25-羟基胆钙化醇一水合物晶体及其制备方法以及使用其的微乳液

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB666106A (en) * 1949-10-12 1952-02-06 Ciba Ltd Process for the manufacture of compounds with semi-cyclic double bond
US3994934A (en) * 1975-01-27 1976-11-30 The Upjohn Company Process for preparing Δ22 -25-oxy substituted sterol derivatives
US3946052A (en) * 1975-06-16 1976-03-23 Stanford Research Institute 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs thereof having postcoital antifertility activity
IT1088094B (it) * 1976-10-14 1985-06-04 Hoffmann La Roche Derivati del pregnano

Also Published As

Publication number Publication date
JPH0440360B2 (ja) 1992-07-02
JPH0543592A (ja) 1993-02-23
DE3171414D1 (en) 1985-08-22
JPH0660195B2 (ja) 1994-08-10
EP0050325A3 (en) 1982-08-18
JPH0228194A (ja) 1990-01-30
US4310467A (en) 1982-01-12
JPH021160B2 (ja) 1990-01-10
EP0050325B1 (de) 1985-07-17
ATE14317T1 (de) 1985-08-15
EP0050325A2 (de) 1982-04-28

Similar Documents

Publication Publication Date Title
JPS5798300A (en) Manufacture of pregnane derivative
WO1988002753A3 (en) 9-alpha-hydroxy steroids and process for their preparation
ES8800263A1 (es) Procedimiento de preparacion de 17-(isociano-sulfonilmetileno)-esteroides
JPS568399A (en) Manufacture of chenodeoxycholic acid
ES486325A1 (es) Procedimiento de preparacion de un esteroide
AU567934B2 (en) Preparation 21-hydroxy-20-keto-delta 16 steroids and intermediates
IL52436A (en) Process for the preparation of cholesta-5,7-diene-3beta,25-diol and 1alpha,3beta,25-triol and corresponding cholesta-5,22-diene-7-ones as intermediates therefor
GB989881A (en) Improvements in or relating to 10 -methyl steroids and the production thereof
AU1403088A (en) 17alpha-ethinyl-17beta-hydroxy-18-methyl-4, 15-estradien-3-one and new intermediate products for this process
Bell et al. A synthesis of 25‐hydroxycholecalciferol‐(26, 27‐3H)
DE3572648D1 (en) Halogen labeled compounds including estradiol derivatives, their synthetic intermediates and the syntheses thereof
Nemoto et al. Convergent and stereoselective synthesis of vitamin D3 via 3, 5-cyclovitamins D3
Yamada et al. Synthesis of 6, 19-epidioxy-9, 10-secoergosta-5 (10), 7, 22-trien-3β-ols from vitamin D derivatives by oxidation with singlet oxygen
AU523501B2 (en) 21 hydroxy 20 oxo 17 alpha pregnanes
JPS51143656A (en) A process for preparing 7-dehydro cholesterol
US3450697A (en) Process for the preparation of 5(10),7-dehydro-steroids
IE42468L (en) 13-ethynyl- and 13-(2 halovinyl)-steroids
HIRANO et al. Synthesis of (22R)-and (22S)-22, 25-dihydroxyvitamin D3 and determination of their biological activity
ES8801837A1 (es) Procedimiento de preparacion de 20-ceto-delta16-esteroides
DE3160507D1 (en) Process for the preparation of 3,20-dioxo-pregn-4-ene and/or 3,20-dioxo-pregna-1,4-diene
JPS54119446A (en) Preparation of estrone
WO1990015067A3 (fr) NOUVEAUX PROCEDES D'OBTENTION DE 6-METHYL 19-NOR STEROIDES ET LEUR CONVERSION EN 19-NOR PREGNADIENES 17α-SUBSTITUES
US3494843A (en) Process for the manufacture of 3-oxo-4-oxa-5-hydroxymethyl-steroids
JPS5467094A (en) Preparation of steroid alcohol
GB931221A (en) Steroid compounds