JPS5788198A - Synthetic intermediate of corticoids - Google Patents

Synthetic intermediate of corticoids

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Publication number
JPS5788198A
JPS5788198A JP16441880A JP16441880A JPS5788198A JP S5788198 A JPS5788198 A JP S5788198A JP 16441880 A JP16441880 A JP 16441880A JP 16441880 A JP16441880 A JP 16441880A JP S5788198 A JPS5788198 A JP S5788198A
Authority
JP
Japan
Prior art keywords
dione
hydroxylamine
pregna
diene
corticoids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP16441880A
Other languages
Japanese (ja)
Inventor
Kazunari Nitta
Toshio Haruyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Chemical Corp
Original Assignee
Mitsubishi Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chemical Industries Ltd filed Critical Mitsubishi Chemical Industries Ltd
Priority to JP16441880A priority Critical patent/JPS5788198A/en
Publication of JPS5788198A publication Critical patent/JPS5788198A/en
Pending legal-status Critical Current

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Abstract

NEW MATERIAL:Pregna-1,4-diene-3,20-dione 20-oxime.
USE: A synthetic intermdiate of adrenocortical hormones such as predonisolone or predonisone.
PREPARATION: For example, pregna-1,4-diene-3,20-dione is dissolved in aqueous methanol and 1W1.05mol, per mol of the dione, of hydroxylamine salt such as hydroxylamine hydrochloride and a base such as sodium acetate are added to the solution and resultantly, the liberating hydroxylamine reacts with the starting compound at -10W+30°C to give the objective compound.
COPYRIGHT: (C)1982,JPO&Japio
JP16441880A 1980-11-21 1980-11-21 Synthetic intermediate of corticoids Pending JPS5788198A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16441880A JPS5788198A (en) 1980-11-21 1980-11-21 Synthetic intermediate of corticoids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16441880A JPS5788198A (en) 1980-11-21 1980-11-21 Synthetic intermediate of corticoids

Publications (1)

Publication Number Publication Date
JPS5788198A true JPS5788198A (en) 1982-06-01

Family

ID=15792764

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16441880A Pending JPS5788198A (en) 1980-11-21 1980-11-21 Synthetic intermediate of corticoids

Country Status (1)

Country Link
JP (1) JPS5788198A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2559156A1 (en) * 1984-02-03 1985-08-09 Roussel Uclaf PROCESS FOR THE PREPARATION OF PREDNISONE DERIVATIVES AND INTERMEDIATE PRODUCTS THEREOF
FR2620708A1 (en) * 1984-02-03 1989-03-24 Roussel Uclaf New industrial products, process for preparing them and their application

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2559156A1 (en) * 1984-02-03 1985-08-09 Roussel Uclaf PROCESS FOR THE PREPARATION OF PREDNISONE DERIVATIVES AND INTERMEDIATE PRODUCTS THEREOF
FR2620708A1 (en) * 1984-02-03 1989-03-24 Roussel Uclaf New industrial products, process for preparing them and their application

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