JPS5788198A - Synthetic intermediate of corticoids - Google Patents
Synthetic intermediate of corticoidsInfo
- Publication number
- JPS5788198A JPS5788198A JP16441880A JP16441880A JPS5788198A JP S5788198 A JPS5788198 A JP S5788198A JP 16441880 A JP16441880 A JP 16441880A JP 16441880 A JP16441880 A JP 16441880A JP S5788198 A JPS5788198 A JP S5788198A
- Authority
- JP
- Japan
- Prior art keywords
- dione
- hydroxylamine
- pregna
- diene
- corticoids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Steroid Compounds (AREA)
Abstract
NEW MATERIAL:Pregna-1,4-diene-3,20-dione 20-oxime.
USE: A synthetic intermdiate of adrenocortical hormones such as predonisolone or predonisone.
PREPARATION: For example, pregna-1,4-diene-3,20-dione is dissolved in aqueous methanol and 1W1.05mol, per mol of the dione, of hydroxylamine salt such as hydroxylamine hydrochloride and a base such as sodium acetate are added to the solution and resultantly, the liberating hydroxylamine reacts with the starting compound at -10W+30°C to give the objective compound.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16441880A JPS5788198A (en) | 1980-11-21 | 1980-11-21 | Synthetic intermediate of corticoids |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16441880A JPS5788198A (en) | 1980-11-21 | 1980-11-21 | Synthetic intermediate of corticoids |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5788198A true JPS5788198A (en) | 1982-06-01 |
Family
ID=15792764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16441880A Pending JPS5788198A (en) | 1980-11-21 | 1980-11-21 | Synthetic intermediate of corticoids |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5788198A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2559156A1 (en) * | 1984-02-03 | 1985-08-09 | Roussel Uclaf | PROCESS FOR THE PREPARATION OF PREDNISONE DERIVATIVES AND INTERMEDIATE PRODUCTS THEREOF |
FR2620708A1 (en) * | 1984-02-03 | 1989-03-24 | Roussel Uclaf | New industrial products, process for preparing them and their application |
-
1980
- 1980-11-21 JP JP16441880A patent/JPS5788198A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2559156A1 (en) * | 1984-02-03 | 1985-08-09 | Roussel Uclaf | PROCESS FOR THE PREPARATION OF PREDNISONE DERIVATIVES AND INTERMEDIATE PRODUCTS THEREOF |
FR2620708A1 (en) * | 1984-02-03 | 1989-03-24 | Roussel Uclaf | New industrial products, process for preparing them and their application |
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