JPS5785389A - Novel antibiotic and its preparation - Google Patents
Novel antibiotic and its preparationInfo
- Publication number
- JPS5785389A JPS5785389A JP55161397A JP16139780A JPS5785389A JP S5785389 A JPS5785389 A JP S5785389A JP 55161397 A JP55161397 A JP 55161397A JP 16139780 A JP16139780 A JP 16139780A JP S5785389 A JPS5785389 A JP S5785389A
- Authority
- JP
- Japan
- Prior art keywords
- substance
- formulai
- gram
- ester
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A desacetyl-KA-6643 substance shown by the formulaI[R is H, or -SO3H; A is -CH=CH-, -CX=CH-(X is halogen), etc.; n is 0 or 1] or its salt or its ester.
USE: An antibacterial agent and a β-lactamase inhibitor. Having antibacterial action on Gram-positive and Gram-negative bacteria. Having extremely higher stability in a living body than that of KA-6643 substance.
PROCESS: An N-acetyl group is removed from a KA-6643 substance shown by the formula II, its salt, or its ester, to give a compound shown by the formulaI. The removal is carried out using amidohydlase (e.g., enzyme, mold, or treated mold having an N-acetyl group hydrolyzing ability). The compound shown by the formula II is obtained from Streptomyces sp.KC-6643(FERM-P4467).
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55161397A JPS5785389A (en) | 1980-11-18 | 1980-11-18 | Novel antibiotic and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55161397A JPS5785389A (en) | 1980-11-18 | 1980-11-18 | Novel antibiotic and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5785389A true JPS5785389A (en) | 1982-05-28 |
Family
ID=15734309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55161397A Pending JPS5785389A (en) | 1980-11-18 | 1980-11-18 | Novel antibiotic and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5785389A (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4630570Y1 (en) * | 1968-10-03 | 1971-10-22 | ||
JPS4931527U (en) * | 1972-06-19 | 1974-03-19 | ||
JPS5065347A (en) * | 1973-10-09 | 1975-06-03 |
-
1980
- 1980-11-18 JP JP55161397A patent/JPS5785389A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4630570Y1 (en) * | 1968-10-03 | 1971-10-22 | ||
JPS4931527U (en) * | 1972-06-19 | 1974-03-19 | ||
JPS5065347A (en) * | 1973-10-09 | 1975-06-03 |
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