JPS5785389A - Novel antibiotic and its preparation - Google Patents

Novel antibiotic and its preparation

Info

Publication number
JPS5785389A
JPS5785389A JP55161397A JP16139780A JPS5785389A JP S5785389 A JPS5785389 A JP S5785389A JP 55161397 A JP55161397 A JP 55161397A JP 16139780 A JP16139780 A JP 16139780A JP S5785389 A JPS5785389 A JP S5785389A
Authority
JP
Japan
Prior art keywords
substance
formulai
gram
ester
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP55161397A
Other languages
Japanese (ja)
Inventor
Masato Nakayama
Shigeru Kimura
Toshimi Mizoguchi
Sohei Tanabe
Toshito Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KOUWA KK
Kowa Co Ltd
Original Assignee
KOUWA KK
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KOUWA KK, Kowa Co Ltd filed Critical KOUWA KK
Priority to JP55161397A priority Critical patent/JPS5785389A/en
Publication of JPS5785389A publication Critical patent/JPS5785389A/en
Pending legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A desacetyl-KA-6643 substance shown by the formulaI[R is H, or -SO3H; A is -CH=CH-, -CX=CH-(X is halogen), etc.; n is 0 or 1] or its salt or its ester.
USE: An antibacterial agent and a β-lactamase inhibitor. Having antibacterial action on Gram-positive and Gram-negative bacteria. Having extremely higher stability in a living body than that of KA-6643 substance.
PROCESS: An N-acetyl group is removed from a KA-6643 substance shown by the formula II, its salt, or its ester, to give a compound shown by the formulaI. The removal is carried out using amidohydlase (e.g., enzyme, mold, or treated mold having an N-acetyl group hydrolyzing ability). The compound shown by the formula II is obtained from Streptomyces sp.KC-6643(FERM-P4467).
COPYRIGHT: (C)1982,JPO&Japio
JP55161397A 1980-11-18 1980-11-18 Novel antibiotic and its preparation Pending JPS5785389A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55161397A JPS5785389A (en) 1980-11-18 1980-11-18 Novel antibiotic and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55161397A JPS5785389A (en) 1980-11-18 1980-11-18 Novel antibiotic and its preparation

Publications (1)

Publication Number Publication Date
JPS5785389A true JPS5785389A (en) 1982-05-28

Family

ID=15734309

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55161397A Pending JPS5785389A (en) 1980-11-18 1980-11-18 Novel antibiotic and its preparation

Country Status (1)

Country Link
JP (1) JPS5785389A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4630570Y1 (en) * 1968-10-03 1971-10-22
JPS4931527U (en) * 1972-06-19 1974-03-19
JPS5065347A (en) * 1973-10-09 1975-06-03

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4630570Y1 (en) * 1968-10-03 1971-10-22
JPS4931527U (en) * 1972-06-19 1974-03-19
JPS5065347A (en) * 1973-10-09 1975-06-03

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