JPS5785320A - Immobilized immuno-active substance and its preparation - Google Patents

Immobilized immuno-active substance and its preparation

Info

Publication number
JPS5785320A
JPS5785320A JP55161372A JP16137280A JPS5785320A JP S5785320 A JPS5785320 A JP S5785320A JP 55161372 A JP55161372 A JP 55161372A JP 16137280 A JP16137280 A JP 16137280A JP S5785320 A JPS5785320 A JP S5785320A
Authority
JP
Japan
Prior art keywords
fiber
active substance
immuno
antigen
acrylonitrile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55161372A
Other languages
Japanese (ja)
Other versions
JPH022613B2 (en
Inventor
Shuntaro Hosaka
Yasuo Murao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Priority to JP55161372A priority Critical patent/JPS5785320A/en
Publication of JPS5785320A publication Critical patent/JPS5785320A/en
Publication of JPH022613B2 publication Critical patent/JPH022613B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PURPOSE: To prepare the titled immuno-active substance, easily and economically by bonding an immuno-active substance to the surface of a solid carrier consisting of the partial hydrolyzate of acrylonitrile fiber.
CONSTITUTION: Partially hydrolyzed acrylonitrile fiber (modacryl fiber containing ≤50wt% acrylonitrile can also be used) is used as a solid carrier, and an immuno-active substance (e.g. treponema pallidum antigen, hepatitis B surface antigen, rubella antigen, etc.) is bonded to the surface of the carrier through covalent bond to obtain the immobilized immuno-active substance. The partial hydrolyzate can be obtained by partially hydrolyzing an acylonitrile fiber with an acid or alkali catalyst to an extent that the dissolution of the fiber does not take place, thereby forming carbamoyl groups to the surface of the fiber. The subsequent immobilization is pref. carried out by reacting the resultant carbamoyl group with dialdehyde, and then immobilizing the immuno-active substance through the dialdehyde to the fiber surface.
COPYRIGHT: (C)1982,JPO&Japio
JP55161372A 1980-11-18 1980-11-18 Immobilized immuno-active substance and its preparation Granted JPS5785320A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55161372A JPS5785320A (en) 1980-11-18 1980-11-18 Immobilized immuno-active substance and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55161372A JPS5785320A (en) 1980-11-18 1980-11-18 Immobilized immuno-active substance and its preparation

Publications (2)

Publication Number Publication Date
JPS5785320A true JPS5785320A (en) 1982-05-28
JPH022613B2 JPH022613B2 (en) 1990-01-18

Family

ID=15733828

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55161372A Granted JPS5785320A (en) 1980-11-18 1980-11-18 Immobilized immuno-active substance and its preparation

Country Status (1)

Country Link
JP (1) JPS5785320A (en)

Also Published As

Publication number Publication date
JPH022613B2 (en) 1990-01-18

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