JPS5782399A - 2-deoxystreptamine aminoglycoside derivative and manufacture - Google Patents
2-deoxystreptamine aminoglycoside derivative and manufactureInfo
- Publication number
- JPS5782399A JPS5782399A JP56148681A JP14868181A JPS5782399A JP S5782399 A JPS5782399 A JP S5782399A JP 56148681 A JP56148681 A JP 56148681A JP 14868181 A JP14868181 A JP 14868181A JP S5782399 A JPS5782399 A JP S5782399A
- Authority
- JP
- Japan
- Prior art keywords
- alpha
- protected
- beta
- amino
- aprosaminide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18944080A | 1980-09-22 | 1980-09-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5782399A true JPS5782399A (en) | 1982-05-22 |
Family
ID=22697337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56148681A Pending JPS5782399A (en) | 1980-09-22 | 1981-09-19 | 2-deoxystreptamine aminoglycoside derivative and manufacture |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0048613B1 (ja) |
JP (1) | JPS5782399A (ja) |
AT (1) | ATE11416T1 (ja) |
DE (1) | DE3168509D1 (ja) |
GB (1) | GB2084149B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017018528A1 (ja) * | 2015-07-30 | 2017-02-02 | 公益財団法人 微生物化学研究会 | 多剤耐性菌に有効な新規アミノグリコシド抗生物質 |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4468513A (en) * | 1980-09-22 | 1984-08-28 | Eli Lilly And Company | 2'-N-Acylated and 2'-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides |
US4482707A (en) * | 1981-12-08 | 1984-11-13 | Toyo Jozo Kabushiki Kaisha | Aminoglycoside antibiotic saccharocins |
IT1200774B (it) * | 1985-10-10 | 1989-01-27 | Pierrel Spa | Procedimento di sentisi dell'amikacina |
-
1981
- 1981-09-19 JP JP56148681A patent/JPS5782399A/ja active Pending
- 1981-09-21 AT AT81304323T patent/ATE11416T1/de not_active IP Right Cessation
- 1981-09-21 EP EP81304323A patent/EP0048613B1/en not_active Expired
- 1981-09-21 GB GB8128464A patent/GB2084149B/en not_active Expired
- 1981-09-21 DE DE8181304323T patent/DE3168509D1/de not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017018528A1 (ja) * | 2015-07-30 | 2017-02-02 | 公益財団法人 微生物化学研究会 | 多剤耐性菌に有効な新規アミノグリコシド抗生物質 |
US10617704B2 (en) | 2015-07-30 | 2020-04-14 | Microbial Chemistry Research Foundation | Effective aminoglycoside antibiotic for multidrug-resistant bacteria |
US11135234B2 (en) | 2015-07-30 | 2021-10-05 | Microbial Chemistry Research Foundation | Effective aminoglycoside antibiotic for multidrug-resistant bacteria |
Also Published As
Publication number | Publication date |
---|---|
EP0048613A1 (en) | 1982-03-31 |
GB2084149B (en) | 1984-08-15 |
ATE11416T1 (de) | 1985-02-15 |
GB2084149A (en) | 1982-04-07 |
EP0048613B1 (en) | 1985-01-23 |
DE3168509D1 (en) | 1985-03-07 |
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