JPS5775976A - Novel heterocyclic derivative, manufacture and medicinal composition containing same - Google Patents

Novel heterocyclic derivative, manufacture and medicinal composition containing same

Info

Publication number
JPS5775976A
JPS5775976A JP56134809A JP13480981A JPS5775976A JP S5775976 A JPS5775976 A JP S5775976A JP 56134809 A JP56134809 A JP 56134809A JP 13480981 A JP13480981 A JP 13480981A JP S5775976 A JPS5775976 A JP S5775976A
Authority
JP
Japan
Prior art keywords
manufacture
composition containing
medicinal composition
containing same
heterocyclic derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56134809A
Other languages
English (en)
Inventor
Jiyon Puraisu Barii
Watoson Kurizerou Jiyon
Buratsudoshiyoo Jiyon
Maachin Sumisu Maikeru
Edomondo Beizu Debitsudo
Karei Rinda
Buratsuchiyaa Fuiritsupu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JPS5775976A publication Critical patent/JPS5775976A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP56134809A 1980-08-27 1981-08-27 Novel heterocyclic derivative, manufacture and medicinal composition containing same Pending JPS5775976A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8027741 1980-08-27

Publications (1)

Publication Number Publication Date
JPS5775976A true JPS5775976A (en) 1982-05-12

Family

ID=10515679

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56134809A Pending JPS5775976A (en) 1980-08-27 1981-08-27 Novel heterocyclic derivative, manufacture and medicinal composition containing same

Country Status (6)

Country Link
US (1) US4481199A (ja)
EP (1) EP0048555B1 (ja)
JP (1) JPS5775976A (ja)
AU (1) AU548426B2 (ja)
DE (1) DE3173130D1 (ja)
ZA (1) ZA815964B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0070097A1 (en) * 1981-06-11 1983-01-19 Glaxo Group Limited 1,2,4-Triazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
EP0070743A3 (en) * 1981-07-22 1983-10-12 Glaxo Group Limited Pharmaceutical compositions containing compounds having action on histamine receptors
JPS6067474A (ja) * 1983-09-24 1985-04-17 Wakamoto Pharmaceut Co Ltd 新規な１，３，４−チアジアゾ−ル誘導体及びそれを有効成分とする抗潰瘍剤
DE3336410A1 (de) * 1983-10-06 1985-04-18 Ludwig Heumann & Co GmbH, 8500 Nürnberg Sulfenamidderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3441086A1 (de) * 1984-11-09 1986-05-15 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3,4-diazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3926119A1 (de) * 1989-08-08 1991-02-14 Bayer Ag 3-amino-5-aminocarbonyl-1,2,4-triazol-derivate
US5234897A (en) * 1989-03-15 1993-08-10 Bayer Aktiengesellschaft Herbicidal 3-amino-5-aminocarbonyl-1,2,4-triazoles
CA2469042A1 (en) 2001-12-20 2003-07-03 Applied Research Systems Ars Holding N.V. Triazoles as oxytocin antagonists
MX2011000671A (es) * 2008-07-18 2011-04-11 Sanofi Aventis Nuevos derivados de triazolo [4,3-a] piridina su procedimiento de preparacion, su uso como medicamentos, composiciones farmaceuticas y nuevo uso particularmente como inhibidores de met.
FR2941229B1 (fr) * 2009-01-21 2012-11-30 Sanofi Aventis Nouveaux derives triazolo°4,3-a!pyridine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de met
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2835695A1 (de) * 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
GB2023133B (en) * 1978-04-26 1982-09-08 Glaxo Group Ltd Heterocyclic derivatives
ZA801151B (en) * 1979-03-02 1981-02-25 Glaxo Group Ltd Heterocyclic derivatives
NO800583L (no) * 1979-03-02 1980-09-03 Glaxo Group Ltd Fremgangsmaate for fremstilling av farmakologisk aktive triazolderivater
DE3067564D1 (en) * 1979-10-22 1984-05-24 Glaxo Group Ltd 1,2,4-triazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
DE3070073D1 (en) * 1979-10-22 1985-03-14 Glaxo Group Ltd 1,2,4-triazole derivatives, processes for their production and pharmaceutical compositions containing them
EP0027744B1 (en) * 1979-10-23 1984-03-14 Glaxo Group Limited Thiophene derivatives, processes for the production thereof and pharmaceutical compositions containing them
GB2064515B (en) * 1979-10-23 1983-06-29 Glaxo Group Ltd Heterocyclic derivatives processes for their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE3173130D1 (en) 1986-01-16
AU7474981A (en) 1982-03-04
ZA815964B (en) 1983-04-27
EP0048555A1 (en) 1982-03-31
AU548426B2 (en) 1985-12-12
US4481199A (en) 1984-11-06
EP0048555B1 (en) 1985-12-04

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