DE3173130D1 - Amino-1,2,4-triazole derivatives, processes for their preparation and pharmaceutical compositions containing them - Google Patents

Amino-1,2,4-triazole derivatives, processes for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE3173130D1
DE3173130D1 DE8181303930T DE3173130T DE3173130D1 DE 3173130 D1 DE3173130 D1 DE 3173130D1 DE 8181303930 T DE8181303930 T DE 8181303930T DE 3173130 T DE3173130 T DE 3173130T DE 3173130 D1 DE3173130 D1 DE 3173130D1
Authority
DE
Germany
Prior art keywords
amino
processes
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181303930T
Other languages
English (en)
Inventor
Linda Carey
Michael Martin-Smith
Barry John Price
Philip Blatcher
John Watson Clitherow
David Edmund Bays
John Bradshaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE3173130D1 publication Critical patent/DE3173130D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8181303930T 1980-08-27 1981-08-27 Amino-1,2,4-triazole derivatives, processes for their preparation and pharmaceutical compositions containing them Expired DE3173130D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8027741 1980-08-27

Publications (1)

Publication Number Publication Date
DE3173130D1 true DE3173130D1 (en) 1986-01-16

Family

ID=10515679

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181303930T Expired DE3173130D1 (en) 1980-08-27 1981-08-27 Amino-1,2,4-triazole derivatives, processes for their preparation and pharmaceutical compositions containing them

Country Status (6)

Country Link
US (1) US4481199A (de)
EP (1) EP0048555B1 (de)
JP (1) JPS5775976A (de)
AU (1) AU548426B2 (de)
DE (1) DE3173130D1 (de)
ZA (1) ZA815964B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1173032A (en) * 1981-06-11 1984-08-21 Glaxo Group Limited Heterocyclic derivatives as histamine h.sub.2- antagonists
EP0070743A3 (de) * 1981-07-22 1983-10-12 Glaxo Group Limited Pharmazeutische Zusammensetzungen, die Verbindungen enthalten, die auf Histamin-Rezeptoren einwirken
JPS6067474A (ja) * 1983-09-24 1985-04-17 Wakamoto Pharmaceut Co Ltd 新規な１，３，４−チアジアゾ−ル誘導体及びそれを有効成分とする抗潰瘍剤
DE3336410A1 (de) * 1983-10-06 1985-04-18 Ludwig Heumann & Co GmbH, 8500 Nürnberg Sulfenamidderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3441086A1 (de) * 1984-11-09 1986-05-15 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3,4-diazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5234897A (en) * 1989-03-15 1993-08-10 Bayer Aktiengesellschaft Herbicidal 3-amino-5-aminocarbonyl-1,2,4-triazoles
DE3926119A1 (de) * 1989-08-08 1991-02-14 Bayer Ag 3-amino-5-aminocarbonyl-1,2,4-triazol-derivate
SI1458381T1 (sl) 2001-12-20 2006-04-30 Applied Research Systems Triazoli kot oksitocinski antagonisti
FR2941229B1 (fr) * 2009-01-21 2012-11-30 Sanofi Aventis Nouveaux derives triazolo°4,3-a!pyridine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de met
WO2010007316A2 (fr) * 2008-07-18 2010-01-21 Sanofi-Aventis NOUVEAUX DERIVES TRIAZOLO(4,3-a)PYRIDINE,LEUR PROCEDE DE PREPARATION,LEUR APPLICATION A TITRE DE MEDICAMENTS,COMPOSITIONS PHARMACEUTIQUES ET NOUVELLE UTILISATION NOTAMMENT COMME INHIBITEURS DE MET
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2835695A1 (de) * 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
GB2023133B (en) * 1978-04-26 1982-09-08 Glaxo Group Ltd Heterocyclic derivatives
AU535701B2 (en) * 1979-03-02 1984-04-05 Glaxo Group Limited Amino trialole derivatives
ZA801151B (en) * 1979-03-02 1981-02-25 Glaxo Group Ltd Heterocyclic derivatives
EP0029303B1 (de) * 1979-10-22 1985-01-30 Glaxo Group Limited 1,2,4-Triazol-derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DK446980A (da) * 1979-10-22 1981-04-23 Glaxo Group Ltd R fremgangsmaade til fremstilling af heterocycliske forbindelse
EP0029306B1 (de) * 1979-10-23 1984-07-25 Glaxo Group Limited Aminoalkylverbindungen, deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DE3067019D1 (en) * 1979-10-23 1984-04-19 Glaxo Group Ltd Thiophene derivatives, processes for the production thereof and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPS5775976A (en) 1982-05-12
EP0048555A1 (de) 1982-03-31
ZA815964B (en) 1983-04-27
EP0048555B1 (de) 1985-12-04
AU7474981A (en) 1982-03-04
AU548426B2 (en) 1985-12-12
US4481199A (en) 1984-11-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee