JPS5767531A - Alpha-hydroxyalkanophenone acetal - Google Patents

Alpha-hydroxyalkanophenone acetal

Info

Publication number
JPS5767531A
JPS5767531A JP14304180A JP14304180A JPS5767531A JP S5767531 A JPS5767531 A JP S5767531A JP 14304180 A JP14304180 A JP 14304180A JP 14304180 A JP14304180 A JP 14304180A JP S5767531 A JPS5767531 A JP S5767531A
Authority
JP
Japan
Prior art keywords
expressed
acetal
formula
hydroxyalkanophenone
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14304180A
Other languages
Japanese (ja)
Inventor
Genichi Dobashi
Shuichi Mitamura
Atsuji Kitajima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Priority to JP14304180A priority Critical patent/JPS5767531A/en
Publication of JPS5767531A publication Critical patent/JPS5767531A/en
Pending legal-status Critical Current

Links

Landscapes

  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:An α-hydroxyalkanophenone acetal expressed by formulaI(R is alkyl or alkoxyl; R1, R2 and R3 lower alkyl; R1 and R2 together may form a cyclic acetal).
EXAMPLE: α-Hydroxyl-p-isobutylpropiophenone dimethyl acetal.
USE: An intermediate for an anti-inflammatory and analgesic agent, etc.
PROCESS: A haloketone expressed by formula II is reacted with an alkaline metallic alkoxide expressed by the formula R1OM (M is alkali metal) in the presence of the corresponding alcohol expressed by the formula ROH. The use of the novel compound provides a compound expressed by formula III (R5 is H or lower alkyl), e.g. ibuprofen, in high yield in a safe and short step.
COPYRIGHT: (C)1982,JPO&Japio
JP14304180A 1980-10-15 1980-10-15 Alpha-hydroxyalkanophenone acetal Pending JPS5767531A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14304180A JPS5767531A (en) 1980-10-15 1980-10-15 Alpha-hydroxyalkanophenone acetal

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14304180A JPS5767531A (en) 1980-10-15 1980-10-15 Alpha-hydroxyalkanophenone acetal

Publications (1)

Publication Number Publication Date
JPS5767531A true JPS5767531A (en) 1982-04-24

Family

ID=15329525

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14304180A Pending JPS5767531A (en) 1980-10-15 1980-10-15 Alpha-hydroxyalkanophenone acetal

Country Status (1)

Country Link
JP (1) JPS5767531A (en)

Similar Documents

Publication Publication Date Title
JPS57131791A (en) Benzodiazepine derivative and its preparation
JPS52131540A (en) Phenoxyvaleric acid derivatives and herbicides therefrom
JPS52133968A (en) Cyclopentadiene derivatives
JPS5767531A (en) Alpha-hydroxyalkanophenone acetal
JPS5793962A (en) Carbostyryl derivative
JPS5410399A (en) Preparation of polyalkylene glycol derivative
JPS54128567A (en) 1-substituted-4-acyl-2-pyrrolecarboxylic acid derivative
JPS57128661A (en) 1-(4-substituted aminophenyl)-2-oxy-1-alkanone acetal
JPS5775948A (en) Production of 2-(substituted phenoxy)phenylacetic acid
JPS5770854A (en) N,n-dialkyl carbamate
JPS57108079A (en) Delta2-1,2,4-triazolin-5-one deriviative, its preparation and use
JPS57131738A (en) Novel cyclohexanecarboxylic acid derivative
JPS57134495A (en) Optically active alkyldiphosphine compound and its preparation
JPS5742643A (en) 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraene-2-ol
JPS5772963A (en) Alpha-(2-pyridyl)arylacetaldehyde
JPS5436274A (en) Preparation of propiophenone derivative
JPS5448743A (en) Preparation of benzoin ether
JPS57134457A (en) Polyprenyl acetoxime derivative and its preparation
JPS57206644A (en) Preparation of 4-(4- (anilino)phenoxy)-2-pentenoic acid derivative
JPS56115735A (en) Preparation of jasmone
JPS5764647A (en) 1-(o(2',6'-dichloroanilino)phenyl)-2,2-dihalogenoethylene
JPS57188541A (en) Ether derivative of cyclopentenone compound
JPS5346922A (en) Separation of boron and fluorine in trifuloroboron
JPS57183730A (en) Liquid crystal compound
JPS549204A (en) Preparation of aminocarboxylic acid ester of secondary or tertiary alcohol