JPS5742649A - Novel anthracyclinone derivative - Google Patents
Novel anthracyclinone derivativeInfo
- Publication number
- JPS5742649A JPS5742649A JP12051880A JP12051880A JPS5742649A JP S5742649 A JPS5742649 A JP S5742649A JP 12051880 A JP12051880 A JP 12051880A JP 12051880 A JP12051880 A JP 12051880A JP S5742649 A JPS5742649 A JP S5742649A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- compound shown
- novel
- diol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A compound shown by the formula [R1 is halogen or -OR2(R2 is H or lower alkanoyl)].
EXAMPLE: 5, 7, 8, 9, 10, 12-Hexahydro-5,12-dioxo-6,11-diol-7,9-cis-diol-9-bromoacetylnaphthacene.
USE: An intermediate for preparing 4-desmethoxyadriamycin, a carcinostatic agent, etc.
PROCESS: A compound shown by the formula II is halogenated so that -CH3 is converted into -CH2X(X is halogen), and the compound is reacted with a compound of R2OH or its metal salt, to give a compound shown by the formula III.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12051880A JPS5742649A (en) | 1980-08-29 | 1980-08-29 | Novel anthracyclinone derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12051880A JPS5742649A (en) | 1980-08-29 | 1980-08-29 | Novel anthracyclinone derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5742649A true JPS5742649A (en) | 1982-03-10 |
Family
ID=14788213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12051880A Pending JPS5742649A (en) | 1980-08-29 | 1980-08-29 | Novel anthracyclinone derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5742649A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63115841A (en) * | 1986-10-31 | 1988-05-20 | Sagami Chem Res Center | 2-(2-fluoroalkyl)-2,5,12-trihydroxy-1,2,3,4-tetrahydro-naphthacene-6,11-dione derivative |
-
1980
- 1980-08-29 JP JP12051880A patent/JPS5742649A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63115841A (en) * | 1986-10-31 | 1988-05-20 | Sagami Chem Res Center | 2-(2-fluoroalkyl)-2,5,12-trihydroxy-1,2,3,4-tetrahydro-naphthacene-6,11-dione derivative |
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