JPS5742649A - Novel anthracyclinone derivative - Google Patents

Novel anthracyclinone derivative

Info

Publication number
JPS5742649A
JPS5742649A JP12051880A JP12051880A JPS5742649A JP S5742649 A JPS5742649 A JP S5742649A JP 12051880 A JP12051880 A JP 12051880A JP 12051880 A JP12051880 A JP 12051880A JP S5742649 A JPS5742649 A JP S5742649A
Authority
JP
Japan
Prior art keywords
compound
formula
compound shown
novel
diol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12051880A
Other languages
Japanese (ja)
Inventor
Michihisa Muramatsu
Hiromi Sato
Kikuo Ishizumi
Sumimoto Katsube
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP12051880A priority Critical patent/JPS5742649A/en
Publication of JPS5742649A publication Critical patent/JPS5742649A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A compound shown by the formula [R1 is halogen or -OR2(R2 is H or lower alkanoyl)].
EXAMPLE: 5, 7, 8, 9, 10, 12-Hexahydro-5,12-dioxo-6,11-diol-7,9-cis-diol-9-bromoacetylnaphthacene.
USE: An intermediate for preparing 4-desmethoxyadriamycin, a carcinostatic agent, etc.
PROCESS: A compound shown by the formula II is halogenated so that -CH3 is converted into -CH2X(X is halogen), and the compound is reacted with a compound of R2OH or its metal salt, to give a compound shown by the formula III.
COPYRIGHT: (C)1982,JPO&Japio
JP12051880A 1980-08-29 1980-08-29 Novel anthracyclinone derivative Pending JPS5742649A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12051880A JPS5742649A (en) 1980-08-29 1980-08-29 Novel anthracyclinone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12051880A JPS5742649A (en) 1980-08-29 1980-08-29 Novel anthracyclinone derivative

Publications (1)

Publication Number Publication Date
JPS5742649A true JPS5742649A (en) 1982-03-10

Family

ID=14788213

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12051880A Pending JPS5742649A (en) 1980-08-29 1980-08-29 Novel anthracyclinone derivative

Country Status (1)

Country Link
JP (1) JPS5742649A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63115841A (en) * 1986-10-31 1988-05-20 Sagami Chem Res Center 2-(2-fluoroalkyl)-2,5,12-trihydroxy-1,2,3,4-tetrahydro-naphthacene-6,11-dione derivative

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63115841A (en) * 1986-10-31 1988-05-20 Sagami Chem Res Center 2-(2-fluoroalkyl)-2,5,12-trihydroxy-1,2,3,4-tetrahydro-naphthacene-6,11-dione derivative

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