JPS57126498A - Novel tylosin derivative - Google Patents

Novel tylosin derivative

Info

Publication number
JPS57126498A
JPS57126498A JP56000574A JP57481A JPS57126498A JP S57126498 A JPS57126498 A JP S57126498A JP 56000574 A JP56000574 A JP 56000574A JP 57481 A JP57481 A JP 57481A JP S57126498 A JPS57126498 A JP S57126498A
Authority
JP
Japan
Prior art keywords
alkanoyloxy
tetrahydropyranyl
tylonolide
tylosin derivative
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56000574A
Other languages
Japanese (ja)
Other versions
JPS637198B2 (en
Inventor
Akihiro Tanaka
Osamu Tsuchiya
Sumio Umezawa
Hamao Umezawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP56000574A priority Critical patent/JPS57126498A/en
Priority to US06/285,747 priority patent/US4438109A/en
Priority to DE19813129112 priority patent/DE3129112A1/en
Priority to CA000382401A priority patent/CA1202621A/en
Priority to GB8122796A priority patent/GB2081711B/en
Priority to CH4830/81A priority patent/CH650513A5/en
Priority to ES81504282A priority patent/ES8301975A1/en
Priority to FR8114456A priority patent/FR2495620A1/en
Priority to ES82514429A priority patent/ES514429A0/en
Publication of JPS57126498A publication Critical patent/JPS57126498A/en
Publication of JPS637198B2 publication Critical patent/JPS637198B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by the formulaI(R1 is tetrahydropyranyl or tetrahydrofuranyloxy; R2 and R3 are H or alkanoyloxy; R4 is H, OH, or alkanoyloxy; with the proviso that when R1 is tetrahydropyranyloxy, R4 is H).
EXAMPLE: A 23-O-tetrahydropyranyl-4'-deoxymycaminosyl tylonolide shown by the formula III.
USE: An antibacterial agent.
PROCESS: For example, a mycaminosyl tylonolide shown by the formula II and dihydropyran or dihydrofuran as raw materials are reacted in a nonproton solvent (e.g., methylene chloride, DMF, etc.) in the presence of a salt of a strong acid and a weak base(preferable pyridinium p-toluenesulfonate, etc.).
COPYRIGHT: (C)1982,JPO&Japio
JP56000574A 1980-07-25 1981-01-06 Novel tylosin derivative Granted JPS57126498A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP56000574A JPS57126498A (en) 1981-01-06 1981-01-06 Novel tylosin derivative
US06/285,747 US4438109A (en) 1980-07-25 1981-07-22 Tylosin derivatives
DE19813129112 DE3129112A1 (en) 1980-07-25 1981-07-23 TYLOSIN DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
CA000382401A CA1202621A (en) 1980-07-25 1981-07-23 Process for producing tylosin derivatives
GB8122796A GB2081711B (en) 1980-07-25 1981-07-23 Tylosin derivatives
CH4830/81A CH650513A5 (en) 1980-07-25 1981-07-24 TYLOSIN DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF.
ES81504282A ES8301975A1 (en) 1980-07-25 1981-07-24 A procedure for the production of a tilosine derivative (Machine-translation by Google Translate, not legally binding)
FR8114456A FR2495620A1 (en) 1980-07-25 1981-07-24 DERIVATIVES OF TYLOSINE
ES82514429A ES514429A0 (en) 1980-07-25 1982-07-27 A PROCEDURE FOR THE PRODUCTION OF A THYLOSINE DERIVATIVE.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56000574A JPS57126498A (en) 1981-01-06 1981-01-06 Novel tylosin derivative

Publications (2)

Publication Number Publication Date
JPS57126498A true JPS57126498A (en) 1982-08-06
JPS637198B2 JPS637198B2 (en) 1988-02-15

Family

ID=11477475

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56000574A Granted JPS57126498A (en) 1980-07-25 1981-01-06 Novel tylosin derivative

Country Status (1)

Country Link
JP (1) JPS57126498A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6319600U (en) * 1986-07-21 1988-02-09

Also Published As

Publication number Publication date
JPS637198B2 (en) 1988-02-15

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