JPS5735870B2 - - Google Patents
Info
- Publication number
- JPS5735870B2 JPS5735870B2 JP13337977A JP13337977A JPS5735870B2 JP S5735870 B2 JPS5735870 B2 JP S5735870B2 JP 13337977 A JP13337977 A JP 13337977A JP 13337977 A JP13337977 A JP 13337977A JP S5735870 B2 JPS5735870 B2 JP S5735870B2
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13337977A JPS5470241A (en) | 1977-11-09 | 1977-11-09 | Guanidinobenzoic acid derivative and its preparation |
| DE19782846251 DE2846251A1 (de) | 1977-11-09 | 1978-10-24 | Guanidinbenzoesaeureverbindungen, verfahren zu deren herstellung und arzneimittel, welche diese enthalten |
| GB7842081A GB2007653B (en) | 1977-11-09 | 1978-10-26 | Guanidinobenzoic acid compounds and process for preparing the same |
| FR7831718A FR2408584A1 (fr) | 1977-11-09 | 1978-11-09 | Composes guanidinobenzoiques et possedant une activite antifibrinolysine et antitrypsine et leur procede de preparation |
| US05/959,276 US4224342A (en) | 1977-11-09 | 1978-11-09 | Guanidinobenzoic acid compounds and process for preparing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13337977A JPS5470241A (en) | 1977-11-09 | 1977-11-09 | Guanidinobenzoic acid derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5470241A JPS5470241A (en) | 1979-06-05 |
| JPS5735870B2 true JPS5735870B2 (OSRAM) | 1982-07-31 |
Family
ID=15103351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13337977A Granted JPS5470241A (en) | 1977-11-09 | 1977-11-09 | Guanidinobenzoic acid derivative and its preparation |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4224342A (OSRAM) |
| JP (1) | JPS5470241A (OSRAM) |
| DE (1) | DE2846251A1 (OSRAM) |
| FR (1) | FR2408584A1 (OSRAM) |
| GB (1) | GB2007653B (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2044760B (en) | 1979-03-01 | 1983-03-23 | Ono Pharmaceutical Co | Guanidinobenzoic acid derivatives |
| US4490388A (en) * | 1981-02-27 | 1984-12-25 | Torii & Co., Ltd. | Amidine compound and anticomplement agent comprising same |
| US4423069A (en) * | 1982-01-20 | 1983-12-27 | University Of Illinois Foundation | Contraceptive method |
| JPS6254A (ja) * | 1985-03-08 | 1987-01-06 | Kanebo Ltd | 新規グアニジノメチルシクロヘキサンカルボン酸誘導体および該化合物を有効成分とする抗潰瘍薬 |
| US4843094A (en) * | 1985-11-12 | 1989-06-27 | Ono Pharmaceutical Co., Ltd. | Derivatives of p-guantidinobenzoic acid and pharmaceutical agents containing them as active ingredient |
| EP0222608B1 (en) * | 1985-11-12 | 1991-09-11 | Ono Pharmaceutical Co., Ltd. | Derivatives of p-guanidinobenzoic acid and pharmaceutical agents containing them as active ingredient |
| US5247084A (en) * | 1985-11-12 | 1993-09-21 | Ono Pharmaceutical Co., Ltd. | Derivatives of p-guanidinobenzoic acid |
| JPH0676373B2 (ja) * | 1985-12-27 | 1994-09-28 | エーザイ株式会社 | グアニジノ安息香酸エステル誘導体 |
| WO1997037969A1 (fr) | 1996-04-10 | 1997-10-16 | Ono Pharmaceutical Co., Ltd. | Inhibiteur de tryptase derives de guanidino |
| US6066673A (en) * | 1998-03-12 | 2000-05-23 | The Procter & Gamble Company | Enzyme inhibitors |
| US6849605B1 (en) * | 1999-03-05 | 2005-02-01 | The Trustees Of University Technology Corporation | Inhibitors of serine protease activity, methods and compositions for treatment of viral infections |
| AU3864000A (en) * | 1999-03-05 | 2000-09-21 | Trustees Of University Technology Corporation, The | Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses |
| AU3511500A (en) | 1999-03-05 | 2000-09-21 | Trustees Of University Technology Corporation, The | Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions |
| US20040220242A1 (en) * | 2003-05-02 | 2004-11-04 | Leland Shapiro | Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions |
| ES2622522T3 (es) * | 2003-08-26 | 2017-07-06 | The Regents Of The University Of Colorado, A Body Corporate | Inhibidores de la actividad proteasa de serina y su uso en métodos y composiciones para el tratamiento de infecciones bacterianas |
| WO2012178102A2 (en) | 2011-06-24 | 2012-12-27 | The Regents Of The Unversity Of Colorado, A Body Corporate | Compositions, methods and uses for alpha-1 antitrypsin fusion molecules |
| AU2013202648B2 (en) | 2012-01-10 | 2016-05-19 | Konkuk University | Compositions, methods and uses for alpha-1 antitrypsin fusion molecules |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1905813A1 (de) * | 1968-07-04 | 1970-03-05 | Akad Wissenschaften Ddr | 3- oder 4-Guanidobenzoesaeurebenzyl- oder -phenylestern und deren Verwendung als Inhibitoren |
| JPS5440534B2 (OSRAM) * | 1972-05-12 | 1979-12-04 | ||
| JPS5116631A (ja) * | 1974-07-31 | 1976-02-10 | Ono Pharmaceutical Co | Guanijinoansokukosanjudotaino seizohoho |
| GB1472700A (en) * | 1974-11-01 | 1977-05-04 | Ono Pharmaceutical Co | Guanidinobehzoic acid derivatives and process for preparing the same |
-
1977
- 1977-11-09 JP JP13337977A patent/JPS5470241A/ja active Granted
-
1978
- 1978-10-24 DE DE19782846251 patent/DE2846251A1/de active Granted
- 1978-10-26 GB GB7842081A patent/GB2007653B/en not_active Expired
- 1978-11-09 US US05/959,276 patent/US4224342A/en not_active Expired - Lifetime
- 1978-11-09 FR FR7831718A patent/FR2408584A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2408584B1 (OSRAM) | 1983-12-09 |
| US4224342A (en) | 1980-09-23 |
| JPS5470241A (en) | 1979-06-05 |
| FR2408584A1 (fr) | 1979-06-08 |
| GB2007653B (en) | 1982-04-07 |
| DE2846251C2 (OSRAM) | 1988-08-04 |
| GB2007653A (en) | 1979-05-23 |
| DE2846251A1 (de) | 1979-05-10 |