JPS5726587A - Stabilization of ascorbic acid oxidase - Google Patents
Stabilization of ascorbic acid oxidaseInfo
- Publication number
- JPS5726587A JPS5726587A JP10206680A JP10206680A JPS5726587A JP S5726587 A JPS5726587 A JP S5726587A JP 10206680 A JP10206680 A JP 10206680A JP 10206680 A JP10206680 A JP 10206680A JP S5726587 A JPS5726587 A JP S5726587A
- Authority
- JP
- Japan
- Prior art keywords
- ascorbic acid
- acid oxidase
- borate
- stabilization
- pharmaceutical preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 title abstract 4
- 102000004316 Oxidoreductases Human genes 0.000 title abstract 4
- 108090000854 Oxidoreductases Proteins 0.000 title abstract 4
- 235000010323 ascorbic acid Nutrition 0.000 title abstract 4
- 229960005070 ascorbic acid Drugs 0.000 title abstract 4
- 239000011668 ascorbic acid Substances 0.000 title abstract 4
- 230000006641 stabilisation Effects 0.000 title 1
- 238000011105 stabilization Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 3
- 239000004475 Arginine Substances 0.000 abstract 2
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 abstract 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 abstract 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 2
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 abstract 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- 229910021538 borax Inorganic materials 0.000 abstract 1
- -1 e.g. Chemical compound 0.000 abstract 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 abstract 1
- 238000002156 mixing Methods 0.000 abstract 1
- 235000010339 sodium tetraborate Nutrition 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- WUUHFRRPHJEEKV-UHFFFAOYSA-N tripotassium borate Chemical compound [K+].[K+].[K+].[O-]B([O-])[O-] WUUHFRRPHJEEKV-UHFFFAOYSA-N 0.000 abstract 1
- BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Enzymes And Modification Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10206680A JPS5726587A (en) | 1980-07-24 | 1980-07-24 | Stabilization of ascorbic acid oxidase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10206680A JPS5726587A (en) | 1980-07-24 | 1980-07-24 | Stabilization of ascorbic acid oxidase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5726587A true JPS5726587A (en) | 1982-02-12 |
| JPS6112675B2 JPS6112675B2 (enrdf_load_stackoverflow) | 1986-04-09 |
Family
ID=14317385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10206680A Granted JPS5726587A (en) | 1980-07-24 | 1980-07-24 | Stabilization of ascorbic acid oxidase |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5726587A (enrdf_load_stackoverflow) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61242579A (ja) * | 1985-04-22 | 1986-10-28 | Amano Pharmaceut Co Ltd | 安定なアスコルビン酸酸化酵素組成物 |
| JPS62210988A (ja) * | 1986-03-13 | 1987-09-17 | Wako Pure Chem Ind Ltd | キサンチンオキシダ−ゼの安定化方法 |
| JPH05244948A (ja) * | 1992-08-07 | 1993-09-24 | Amano Pharmaceut Co Ltd | アスコルビン酸酸化酵素の安定化方法 |
| EP0565168A3 (enrdf_load_stackoverflow) * | 1992-04-08 | 1994-04-13 | Solvay Enzymes Inc | |
| US5656730A (en) * | 1995-04-07 | 1997-08-12 | Enzon, Inc. | Stabilized monomeric protein compositions |
| US5922912A (en) * | 1996-04-17 | 1999-07-13 | Mitsui Chemicals, Inc. | Concentration method of aqueous acrylamide solution |
-
1980
- 1980-07-24 JP JP10206680A patent/JPS5726587A/ja active Granted
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61242579A (ja) * | 1985-04-22 | 1986-10-28 | Amano Pharmaceut Co Ltd | 安定なアスコルビン酸酸化酵素組成物 |
| JPS62210988A (ja) * | 1986-03-13 | 1987-09-17 | Wako Pure Chem Ind Ltd | キサンチンオキシダ−ゼの安定化方法 |
| EP0565168A3 (enrdf_load_stackoverflow) * | 1992-04-08 | 1994-04-13 | Solvay Enzymes Inc | |
| JPH05244948A (ja) * | 1992-08-07 | 1993-09-24 | Amano Pharmaceut Co Ltd | アスコルビン酸酸化酵素の安定化方法 |
| US5656730A (en) * | 1995-04-07 | 1997-08-12 | Enzon, Inc. | Stabilized monomeric protein compositions |
| US5917021A (en) * | 1995-04-07 | 1999-06-29 | Enzon, Inc. | Stabilized monomeric protein compositions |
| US5922912A (en) * | 1996-04-17 | 1999-07-13 | Mitsui Chemicals, Inc. | Concentration method of aqueous acrylamide solution |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6112675B2 (enrdf_load_stackoverflow) | 1986-04-09 |
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