JPS5721319A - Agent for improving desorder of circulatory orgen - Google Patents

Agent for improving desorder of circulatory orgen

Info

Publication number
JPS5721319A
JPS5721319A JP9733580A JP9733580A JPS5721319A JP S5721319 A JPS5721319 A JP S5721319A JP 9733580 A JP9733580 A JP 9733580A JP 9733580 A JP9733580 A JP 9733580A JP S5721319 A JPS5721319 A JP S5721319A
Authority
JP
Japan
Prior art keywords
ubiquinone
improving
agent
cyclodextrin
clathrate compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9733580A
Other languages
Japanese (ja)
Inventor
Kazuo Matsuda
Yasuo Yonezawa
Hideo Tokugawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ZERIA SHINYAKU KOGYO KK
Zeria Pharmaceutical Co Ltd
Original Assignee
ZERIA SHINYAKU KOGYO KK
Zeria Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ZERIA SHINYAKU KOGYO KK, Zeria Pharmaceutical Co Ltd filed Critical ZERIA SHINYAKU KOGYO KK
Priority to JP9733580A priority Critical patent/JPS5721319A/en
Publication of JPS5721319A publication Critical patent/JPS5721319A/en
Pending legal-status Critical Current

Links

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  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: To prepare an agent for improving the disorder of the circulatory organs, having high stability to light, oxidation, heat, etc., soluble in water, and administrable by injection and orally, by using ubiquinone 50-cyclodextrin clathrate compound as an effective component.
CONSTITUTION: Ubiquinone 50-cyclodextrin clathrate compound which concerns with the energy producing system, is used as an effective component. Ubiquinone 50 is a substance existing exclusively in mitochondria and playing an important role to electron transfer. It is used e.g. as a remedy for cardiac insufficiency, senile cardiopathy, ischemic cardiopathy, etc. The short points of ubiquinone 50 for pharmaceutical preparation, e.g. instability, water-insolubility, etc., are eliminated by clathrating the compound with cyclodextrin. The cyclodextrin moiety of the calthrate is decomposed with α-amylase after administration, and the ubiquinone develops its activity. The clathrate compound is used as an agent for improving the disorder of the circulatory organs in the form of injection, liquid for internal use, tablet, etc.
COPYRIGHT: (C)1982,JPO&Japio
JP9733580A 1980-07-15 1980-07-15 Agent for improving desorder of circulatory orgen Pending JPS5721319A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9733580A JPS5721319A (en) 1980-07-15 1980-07-15 Agent for improving desorder of circulatory orgen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9733580A JPS5721319A (en) 1980-07-15 1980-07-15 Agent for improving desorder of circulatory orgen

Publications (1)

Publication Number Publication Date
JPS5721319A true JPS5721319A (en) 1982-02-04

Family

ID=14189606

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9733580A Pending JPS5721319A (en) 1980-07-15 1980-07-15 Agent for improving desorder of circulatory orgen

Country Status (1)

Country Link
JP (1) JPS5721319A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994022433A1 (en) * 1993-04-02 1994-10-13 Idemitsu Materials Co., Ltd. Broiler ascites preventive and method of preventing ascites
US5951998A (en) * 1997-02-18 1999-09-14 Idemitsu Materials Co., Ltd. Ascites-preventive agent and ascites-preventive method for broilers
WO2005041945A1 (en) * 2003-10-31 2005-05-12 Kaneka Corporation Composition containing reduced coenzyme q

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994022433A1 (en) * 1993-04-02 1994-10-13 Idemitsu Materials Co., Ltd. Broiler ascites preventive and method of preventing ascites
CN1101186C (en) * 1993-04-02 2003-02-12 出光石油化学株式会社 Broiler ascites preventive and method of preventing ascites
US5951998A (en) * 1997-02-18 1999-09-14 Idemitsu Materials Co., Ltd. Ascites-preventive agent and ascites-preventive method for broilers
WO2005041945A1 (en) * 2003-10-31 2005-05-12 Kaneka Corporation Composition containing reduced coenzyme q

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