JPS57206686A - Pyrrolo(2,3-d)carbazole derivative and manufacture - Google Patents

Pyrrolo(2,3-d)carbazole derivative and manufacture

Info

Publication number
JPS57206686A
JPS57206686A JP57070157A JP7015782A JPS57206686A JP S57206686 A JPS57206686 A JP S57206686A JP 57070157 A JP57070157 A JP 57070157A JP 7015782 A JP7015782 A JP 7015782A JP S57206686 A JPS57206686 A JP S57206686A
Authority
JP
Japan
Prior art keywords
pyrrolo
same
manufacture
carbazole derivative
rearrangement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57070157A
Other languages
English (en)
Other versions
JPH0322390B2 (ja
Inventor
Eritsuku Kuun Maachin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Omnichem NV SA
Original Assignee
Omnichem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnichem SA filed Critical Omnichem SA
Publication of JPS57206686A publication Critical patent/JPS57206686A/ja
Publication of JPH0322390B2 publication Critical patent/JPH0322390B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP57070157A 1981-05-04 1982-04-26 Pyrrolo(2,3-d)carbazole derivative and manufacture Granted JPS57206686A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/260,415 US4362739A (en) 1981-05-04 1981-05-04 Pyrrolo(2,3-d)carbazole derivatives, compositions and use

Publications (2)

Publication Number Publication Date
JPS57206686A true JPS57206686A (en) 1982-12-18
JPH0322390B2 JPH0322390B2 (ja) 1991-03-26

Family

ID=22989067

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57070157A Granted JPS57206686A (en) 1981-05-04 1982-04-26 Pyrrolo(2,3-d)carbazole derivative and manufacture

Country Status (6)

Country Link
US (1) US4362739A (ja)
EP (1) EP0064317B1 (ja)
JP (1) JPS57206686A (ja)
AT (1) ATE18226T1 (ja)
CA (1) CA1185605A (ja)
DE (1) DE3269309D1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005531585A (ja) * 2002-05-24 2005-10-20 エックス−セプター セラピューティクス， インコーポレイテッド 薬剤としてのアゼピノインドールおよびピリドインドール誘導体
US8524704B2 (en) 2002-05-24 2013-09-03 Exelixis, Inc. Azepinoindole derivatives as pharmaceutical agents

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU84664A1 (fr) * 1983-02-25 1984-11-08 Onmichem S A Alkyl-4-indolonaphtyridines et leur application therapeutique
US4841045A (en) * 1985-03-12 1989-06-20 University Of Vermont & State Agricultural College Synthesis of vinblastine and vincristine type compounds
WO1986005491A1 (en) * 1985-03-12 1986-09-25 The University Of Vermont And State Agricultural C Synthesis of vinblastine and vincristine type compounds
LU85894A1 (fr) * 1985-05-10 1986-12-05 Omnichem Sa Derives de 1,2,3,4,5,6-hexahydro-azepino (4,5-b) indole leur preparation,composes intermediaires,et leur application en therapeutique
GB9401921D0 (en) * 1994-02-01 1994-03-30 Wellcome Found Heterocyclic compounds
BRPI0412262A (pt) * 2003-07-23 2006-09-19 X Ceptor Therapeutics Inc derivados de azepina como agentes farmacêuticos
US20130178618A1 (en) 2012-01-10 2013-07-11 William Allen Boulanger Novel pharmaceutical intermediates and methods for preparing the same
CN110437238B (zh) * 2019-08-15 2020-10-23 广州大学 一种多环螺吲哚啉化合物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3015661A (en) * 1958-09-04 1962-01-02 Georgian Vlasios Decahydroisoquinoline derivatives
US4154943A (en) * 1977-12-29 1979-05-15 University Of Vermont Preparation of vincadifformine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005531585A (ja) * 2002-05-24 2005-10-20 エックス−セプター セラピューティクス， インコーポレイテッド 薬剤としてのアゼピノインドールおよびピリドインドール誘導体
US8133992B2 (en) 2002-05-24 2012-03-13 Exelixis, Inc. Azepinoindole and pyridoindole derivatives as pharmaceutical agents
US8524704B2 (en) 2002-05-24 2013-09-03 Exelixis, Inc. Azepinoindole derivatives as pharmaceutical agents

Also Published As

Publication number Publication date
EP0064317A3 (en) 1983-04-27
DE3269309D1 (en) 1986-04-03
EP0064317B1 (en) 1986-02-26
JPH0322390B2 (ja) 1991-03-26
EP0064317A2 (en) 1982-11-10
US4362739A (en) 1982-12-07
ATE18226T1 (de) 1986-03-15
CA1185605A (en) 1985-04-16

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