JPS57193499A - 21-haloallene sulfoxide and manufacture - Google Patents

21-haloallene sulfoxide and manufacture

Info

Publication number
JPS57193499A
JPS57193499A JP57083897A JP8389782A JPS57193499A JP S57193499 A JPS57193499 A JP S57193499A JP 57083897 A JP57083897 A JP 57083897A JP 8389782 A JP8389782 A JP 8389782A JP S57193499 A JPS57193499 A JP S57193499A
Authority
JP
Japan
Prior art keywords
haloallene
sulfoxide
manufacture
haloallene sulfoxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57083897A
Other languages
English (en)
Inventor
Aanorudo Uookaa Jierii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of JPS57193499A publication Critical patent/JPS57193499A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
JP57083897A 1981-05-18 1982-05-18 21-haloallene sulfoxide and manufacture Pending JPS57193499A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/264,759 US4342702A (en) 1981-05-18 1981-05-18 Metallated halogenated acetylene corticoid synthesis

Publications (1)

Publication Number Publication Date
JPS57193499A true JPS57193499A (en) 1982-11-27

Family

ID=23007476

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57083897A Pending JPS57193499A (en) 1981-05-18 1982-05-18 21-haloallene sulfoxide and manufacture

Country Status (9)

Country Link
US (1) US4342702A (ja)
JP (1) JPS57193499A (ja)
CH (1) CH650517A5 (ja)
DE (1) DE3218289A1 (ja)
FR (1) FR2505847A1 (ja)
GB (1) GB2098614B (ja)
HU (1) HU186020B (ja)
IT (1) IT1152181B (ja)
NL (1) NL8201875A (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61129197A (ja) * 1984-09-17 1986-06-17 シエ−リング・アクチエンゲゼルシヤフト プレグナン誘導体の製造方法

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4401599A (en) * 1981-05-18 1983-08-30 The Upjohn Company Preparation of 21-halo steroids
US4404142A (en) * 1981-05-18 1983-09-13 The Upjohn Company Preparation of corticoids from 17-keto steroids
US4357279A (en) * 1981-05-18 1982-11-02 The Upjohn Company Preparation of corticoids from 17-keto steroids
US4548748A (en) * 1984-02-03 1985-10-22 The Upjohn Company Cyanohydrin process
US4500461A (en) * 1984-02-03 1985-02-19 The Upjohn Company Cyanohydrin process
US4831131A (en) * 1984-02-03 1989-05-16 The Upjohn Company 11β,17α-Dihydroxy-17β-cyano-androstanes
US4585590A (en) * 1984-02-03 1986-04-29 The Upjohn Company Cyanohydrin process
US4600538A (en) * 1984-08-02 1986-07-15 The Upjohn Company Corticosteroids from 17-keto steroids via 20-cyano-Δ17 (20)-pregnanes
WO1993010141A2 (en) * 1991-11-22 1993-05-27 Alcon Laboratories, Inc. Angiostatic steroids

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499013A (en) * 1968-11-04 1970-03-03 Searle & Co 3-oxygenated 21beta-hydrocarbonsulfonyl-pregna-17(20),20-dienes,dehydro and 19-nor derivatives thereof and intermediates thereto
US4041055A (en) * 1975-11-17 1977-08-09 The Upjohn Company Process for the preparation of 17α-hydroxyprogesterones and corticoids from androstenes
FR2374037A1 (fr) * 1976-10-27 1978-07-13 Roussel Uclaf Nouveaux derives steroides 17-spirosultines les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament
US4183924A (en) * 1978-02-27 1980-01-15 Schering Corporation 17α-Chloro-17β-hydrocarbonsulfinyl-1,4-androstadienes and the corresponding 17β-hydrocarbonsulfonyl derivatives and their use as anti-acne agents

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61129197A (ja) * 1984-09-17 1986-06-17 シエ−リング・アクチエンゲゼルシヤフト プレグナン誘導体の製造方法

Also Published As

Publication number Publication date
DE3218289A1 (de) 1982-12-02
IT1152181B (it) 1986-12-31
IT8221290A0 (it) 1982-05-14
FR2505847B1 (ja) 1984-01-06
HU186020B (en) 1985-05-28
GB2098614A (en) 1982-11-24
IT8221290A1 (it) 1983-11-14
NL8201875A (nl) 1982-12-16
CH650517A5 (de) 1985-07-31
GB2098614B (en) 1985-04-11
FR2505847A1 (fr) 1982-11-19
US4342702A (en) 1982-08-03

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