JPS57176940A - Novel color-developing peptide derivative - Google Patents

Novel color-developing peptide derivative

Info

Publication number
JPS57176940A
JPS57176940A JP56062819A JP6281981A JPS57176940A JP S57176940 A JPS57176940 A JP S57176940A JP 56062819 A JP56062819 A JP 56062819A JP 6281981 A JP6281981 A JP 6281981A JP S57176940 A JPS57176940 A JP S57176940A
Authority
JP
Japan
Prior art keywords
leucyl
amino
valyl
compound
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56062819A
Other languages
Japanese (ja)
Inventor
Yoshitsugu Sakata
Masaaki Kida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Wako Pure Chemical Corp
Original Assignee
Wako Pure Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wako Pure Chemical Industries Ltd filed Critical Wako Pure Chemical Industries Ltd
Priority to JP56062819A priority Critical patent/JPS57176940A/en
Publication of JPS57176940A publication Critical patent/JPS57176940A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

NEW MATERIAL:The compound of formulaI(R1 is leucyl, valyl or valyl-leucyl; R2 is H or CH3; R3 and R4 are CH3, C2H5, C2H4OH, etc.).
EXAMPLE: 4-[(t-Butyloxycarbonyl-L-valyl-L-leucyl-glycyl-L-arginyl)amino]-N,N- diethyl-aniline.
USE: A color-developing substrate for the determination of a specific enzymatic activity, and its intermediate. It is insensitive to hemoglobin, etc. in blood specimen, especially icteric blood. Stable in water and buffer solutions.
PROCESS: The objective compound can be prepared by (1) reacting arginine, etc. having protected amino group and guanidino group with a 4-amino-N,N-dialkylaniline derivative in the presence of a condensation agent, and (2) reacting the resultant novel compound of formula II (R1 is protecting group of N-terminal; R2 is derivative of formulaI, etc.) with amino-protected glycine and leucyl-glycine, etc. in the presence of a condensation agent.
COPYRIGHT: (C)1982,JPO&Japio
JP56062819A 1981-04-25 1981-04-25 Novel color-developing peptide derivative Pending JPS57176940A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56062819A JPS57176940A (en) 1981-04-25 1981-04-25 Novel color-developing peptide derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56062819A JPS57176940A (en) 1981-04-25 1981-04-25 Novel color-developing peptide derivative

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP12867882A Division JPS5890535A (en) 1982-07-23 1982-07-23 Novel color-developing peptide derivative

Publications (1)

Publication Number Publication Date
JPS57176940A true JPS57176940A (en) 1982-10-30

Family

ID=13211315

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56062819A Pending JPS57176940A (en) 1981-04-25 1981-04-25 Novel color-developing peptide derivative

Country Status (1)

Country Link
JP (1) JPS57176940A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986001209A2 (en) * 1984-08-02 1986-02-27 Boehringer Mannheim Gmbh NEW p-PHENYLENEDIAMINE PEPTIDES AND REACTANCE CONTAINING THEM FOR THE DETERMINATION OF PROTEASES OF THE BLOOD COAGULATION SYSTEM

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986001209A2 (en) * 1984-08-02 1986-02-27 Boehringer Mannheim Gmbh NEW p-PHENYLENEDIAMINE PEPTIDES AND REACTANCE CONTAINING THEM FOR THE DETERMINATION OF PROTEASES OF THE BLOOD COAGULATION SYSTEM
WO1986001209A3 (en) * 1984-08-02 1986-03-27 Boehringer Mannheim Gmbh New p-phenylenediamine peptides and reactance containing them for the determination of proteases of the blood coagulation system

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