JPS57166559A - Latex reagent and measuring method for latex coagulation reaction - Google Patents
Latex reagent and measuring method for latex coagulation reactionInfo
- Publication number
- JPS57166559A JPS57166559A JP5277981A JP5277981A JPS57166559A JP S57166559 A JPS57166559 A JP S57166559A JP 5277981 A JP5277981 A JP 5277981A JP 5277981 A JP5277981 A JP 5277981A JP S57166559 A JPS57166559 A JP S57166559A
- Authority
- JP
- Japan
- Prior art keywords
- latex
- styrene
- antiserum
- reagent
- sensitized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
PURPOSE:To decrease unpeculiar coagulation, by polymerizing styrene and a compound shown by a certain general formula and also, styrene sulfonate under the existence of ultra fine silicic anhydride without an emulsifier, and sensitizing latex. CONSTITUTION:A 91g styrene, 0.66g sodium styreme sulfonate, 4.5g a compound represented formula A and 0.20g colloidal solution dispersed 0.06g ultra fine silicic anhydride in water, 0.05g potassium persulfate and 450g ion exchanged water, are polymerized at 70 deg.C for 24hr. Thus obtained latex is sensitized after incubation and a phosphoric acid buffer solution added an antiserum of a guinea pig already absorbed an antimanprotein antibody from the antiserum of immune guinea pig by a HBs antigen is added and sensitized latex is dispersed. False positivity appears very little when the intensity of cohesion for a man blood serum containing the HBs antigen by said reagent is measured.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5277981A JPS57166559A (en) | 1981-04-07 | 1981-04-07 | Latex reagent and measuring method for latex coagulation reaction |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5277981A JPS57166559A (en) | 1981-04-07 | 1981-04-07 | Latex reagent and measuring method for latex coagulation reaction |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57166559A true JPS57166559A (en) | 1982-10-14 |
JPS6352708B2 JPS6352708B2 (en) | 1988-10-19 |
Family
ID=12924333
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5277981A Granted JPS57166559A (en) | 1981-04-07 | 1981-04-07 | Latex reagent and measuring method for latex coagulation reaction |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57166559A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5200315A (en) * | 1990-07-25 | 1993-04-06 | Eastman Kodak Company | Particulate biologically active reagent containing polyoxyalkylene side chains, analytical element and methods for use of the reagent |
-
1981
- 1981-04-07 JP JP5277981A patent/JPS57166559A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5200315A (en) * | 1990-07-25 | 1993-04-06 | Eastman Kodak Company | Particulate biologically active reagent containing polyoxyalkylene side chains, analytical element and methods for use of the reagent |
US5330891A (en) * | 1990-07-25 | 1994-07-19 | Eastman Kodak Company | Method for detection of a nucleic acid using particulate reagent having polyoxyalkylene side chains |
Also Published As
Publication number | Publication date |
---|---|
JPS6352708B2 (en) | 1988-10-19 |
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