JPS57146743A - Optical resolving method of (+-)-1-(1-naphthyl)ethylamine - Google Patents
Optical resolving method of (+-)-1-(1-naphthyl)ethylamineInfo
- Publication number
- JPS57146743A JPS57146743A JP3192781A JP3192781A JPS57146743A JP S57146743 A JPS57146743 A JP S57146743A JP 3192781 A JP3192781 A JP 3192781A JP 3192781 A JP3192781 A JP 3192781A JP S57146743 A JPS57146743 A JP S57146743A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- ethylamine
- naphthyl
- chdca
- nea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To resolve the optically active form of the titled compound useful as an optical resolving agent easily in high purity and yield, by converting 1-(1- naphthyl)ethylamine into a salt of cis-1,2-cyclohexanedicarboxylic acid, and optically resolving the resultant salt.
CONSTITUTION: One mole of (±)-1-(1-naphthyl)-ethylamine (hereafter referred to as 1-NEA) is linked with one mole cis-1,2-cyclohexanedicarboxylic acid (hereafter referred to as CHDCA) to give a salt. A crystal of CHDCA salt of either one of the optically active 1-NEA is seeded in the supersaturated solution of the resultant salt to crystallize separate the same kind of the optically active form preferentially. The resultant crystals are resolved if necessary in the presence of an alkali to give optically pure 1-NEA. The alkali metallic salt of the CHDCA can be easily recovered for reuse.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3192781A JPS57146743A (en) | 1981-03-07 | 1981-03-07 | Optical resolving method of (+-)-1-(1-naphthyl)ethylamine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3192781A JPS57146743A (en) | 1981-03-07 | 1981-03-07 | Optical resolving method of (+-)-1-(1-naphthyl)ethylamine |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57146743A true JPS57146743A (en) | 1982-09-10 |
Family
ID=12344599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3192781A Pending JPS57146743A (en) | 1981-03-07 | 1981-03-07 | Optical resolving method of (+-)-1-(1-naphthyl)ethylamine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57146743A (en) |
-
1981
- 1981-03-07 JP JP3192781A patent/JPS57146743A/en active Pending
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