JPS57145876A - Enantioselective synthesis of optically active 14-oxo-e-homo-eburnane derivative - Google Patents

Enantioselective synthesis of optically active 14-oxo-e-homo-eburnane derivative

Info

Publication number
JPS57145876A
JPS57145876A JP56165543A JP16554381A JPS57145876A JP S57145876 A JPS57145876 A JP S57145876A JP 56165543 A JP56165543 A JP 56165543A JP 16554381 A JP16554381 A JP 16554381A JP S57145876 A JPS57145876 A JP S57145876A
Authority
JP
Japan
Prior art keywords
homo
oxo
optically active
enantioselective synthesis
eburnane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56165543A
Other languages
English (en)
Other versions
JPH0323551B2 (ja
Inventor
Saantai Chiyaba
Saboo Rayosu
Karausu Jiyoruji
Saabi Yaanosu
Kureidoru Yaanosu
Fuarukasu Maaria
Nemesu Andoraasu
Chibura Raasuroo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Nyrt
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Nyrt
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt, Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Nyrt
Publication of JPS57145876A publication Critical patent/JPS57145876A/ja
Publication of JPH0323551B2 publication Critical patent/JPH0323551B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
JP56165543A 1980-10-17 1981-10-16 Enantioselective synthesis of optically active 14-oxo-e-homo-eburnane derivative Granted JPS57145876A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU802525A HU183234B (en) 1980-10-17 1980-10-17 Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan

Publications (2)

Publication Number Publication Date
JPS57145876A true JPS57145876A (en) 1982-09-09
JPH0323551B2 JPH0323551B2 (ja) 1991-03-29

Family

ID=10959834

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56165543A Granted JPS57145876A (en) 1980-10-17 1981-10-16 Enantioselective synthesis of optically active 14-oxo-e-homo-eburnane derivative

Country Status (5)

Country Link
US (1) US4399069A (ja)
EP (1) EP0050492B1 (ja)
JP (1) JPS57145876A (ja)
DE (1) DE3165576D1 (ja)
HU (1) HU183234B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX150317A (es) * 1978-11-17 1984-04-16 Unilever Nv Mejoras en bolsa cerrada de material en hoja para detergentes en particulas
JP2851133B2 (ja) * 1989-06-21 1999-01-27 リヒター ゲデオン ベジェセティ ジャール アール．テー． 新規ラセミ及び光学的活性オクタヒドロ―インド―ロ〔２，３―ａ〕テトラヒドロピラニル〔２，３―ｃ〕キノリジンジエステル誘導体及びその調製方法
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
WO2019191776A1 (en) 2018-03-31 2019-10-03 Hall John L Selective anti-cancer agent effective for prevention and treatment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3770724A (en) * 1970-03-31 1973-11-06 Roussel Uclaf Process for preparing pentacyclic alkaloids
AU499923B2 (en) * 1975-06-27 1979-05-03 Richter Gedeon Vegyeszeti Gyar N Indoloquinolizine derivatives & their production
GB2010833B (en) * 1977-11-25 1982-04-15 Scras Homoerburnamine preparation
FR2445328A1 (fr) * 1978-07-12 1980-07-25 Richter Gedeon Vegyeszet Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament
HU178402B (en) * 1978-08-01 1982-04-28 Richter Gedeon Vegyeszet New process for producing okrahydro-indolo-square bracket-2,3-a-square bracket closed-quinolysines
HU181495B (en) * 1979-05-31 1983-07-28 Richter Gedeon Vegyeszet Process for producing hydroxy-imino-eburnane derivatives

Also Published As

Publication number Publication date
US4399069A (en) 1983-08-16
HU183234B (en) 1984-04-28
DE3165576D1 (en) 1984-09-20
JPH0323551B2 (ja) 1991-03-29
EP0050492B1 (en) 1984-08-15
EP0050492A1 (en) 1982-04-28

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