JPS57131766A - Quinoline derivative and use as medicine - Google Patents

Quinoline derivative and use as medicine

Info

Publication number
JPS57131766A
JPS57131766A JP56199472A JP19947281A JPS57131766A JP S57131766 A JPS57131766 A JP S57131766A JP 56199472 A JP56199472 A JP 56199472A JP 19947281 A JP19947281 A JP 19947281A JP S57131766 A JPS57131766 A JP S57131766A
Authority
JP
Japan
Prior art keywords
medicine
quinoline derivative
quinoline
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56199472A
Other languages
English (en)
Japanese (ja)
Inventor
Gooruzuwaashii Jiyon
Jieemusu Rosu Uiriamu
Pomufuretsuto Buaaji Jiyon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of JPS57131766A publication Critical patent/JPS57131766A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
JP56199472A 1980-12-19 1981-12-09 Quinoline derivative and use as medicine Pending JPS57131766A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8040732 1980-12-19

Publications (1)

Publication Number Publication Date
JPS57131766A true JPS57131766A (en) 1982-08-14

Family

ID=10518094

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56199472A Pending JPS57131766A (en) 1980-12-19 1981-12-09 Quinoline derivative and use as medicine

Country Status (10)

Country Link
US (1) US4390541A (cg-RX-API-DMAC7.html)
EP (1) EP0055068B1 (cg-RX-API-DMAC7.html)
JP (1) JPS57131766A (cg-RX-API-DMAC7.html)
CA (1) CA1173445A (cg-RX-API-DMAC7.html)
DE (1) DE3166737D1 (cg-RX-API-DMAC7.html)
DK (1) DK565281A (cg-RX-API-DMAC7.html)
GB (1) GB2089795B (cg-RX-API-DMAC7.html)
GR (1) GR76691B (cg-RX-API-DMAC7.html)
HU (1) HU185329B (cg-RX-API-DMAC7.html)
IL (1) IL64544A (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995023787A1 (en) * 1994-03-01 1995-09-08 Ishihara Sangyo Kaisha, Ltd. Process for producing 5,7-dichloro-4-hydroxyquinoline

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3206146A1 (de) * 1982-02-20 1983-09-01 Vorwerk & Co Interholding Gmbh, 5600 Wuppertal Aerosol-reinigungsmittel
US4478820A (en) * 1982-09-30 1984-10-23 Eli Lilly And Company Anilino-substituted isoquinoline quinones, pharmaceutical compositions and method of use thereof
FR2783826B1 (fr) * 1998-09-29 2002-07-19 Rhodia Chimie Sa Procede de preparation de 4-hydroxyquinoleines et/ou formes tautomeres
KR20040107525A (ko) * 2002-05-14 2004-12-20 더 리전트 오브 더 유니버시티 오브 캘리포니아 치환된 퀴놀론 카르복실산, 이들의 유도체, 그의 작용부위 및 용도
BR122018075478B8 (pt) 2004-06-24 2023-10-31 Vertex Pharma moduladores de transportadores de cassete de ligação de atp
HUE032813T2 (en) 2005-12-28 2017-11-28 Vertex Pharma Solid forms of N- [2,4-bis (1,1-dimethyl ethyl) -5-hydroxyphenyl] -1,4-dihydro-4-oxoquinoline-3-carboxamide
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
US12458635B2 (en) 2008-08-13 2025-11-04 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
CA2865519C (en) 2012-02-27 2018-01-02 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions comprising a solid dispersion of n-[2,4-bis(1,1-dimethylethyl0-5-hydroxyphenyl-1]-1,4-dihydro-4-oxoquinolone-3-carboxamide for treating cystic fibrosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR879283A (fr) * 1941-04-03 1943-02-18 Ig Farbenindustrie Ag Procédé pour la production de produits de condensation
GB830832A (en) 1957-02-15 1960-03-23 Ici Ltd New quinolones and therapeutic compositions containing them
GB1433774A (en) 1973-02-26 1976-04-28 Allen & Hanburys Ltd Heterocyclic compounds apparatus for conveying articles
DE2901336A1 (de) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995023787A1 (en) * 1994-03-01 1995-09-08 Ishihara Sangyo Kaisha, Ltd. Process for producing 5,7-dichloro-4-hydroxyquinoline

Also Published As

Publication number Publication date
EP0055068A1 (en) 1982-06-30
IL64544A0 (en) 1982-03-31
GB2089795A (en) 1982-06-30
US4390541A (en) 1983-06-28
HU185329B (en) 1985-01-28
DE3166737D1 (en) 1984-11-22
EP0055068B1 (en) 1984-10-17
CA1173445A (en) 1984-08-28
IL64544A (en) 1985-05-31
GR76691B (cg-RX-API-DMAC7.html) 1984-08-24
DK565281A (da) 1982-06-20
GB2089795B (en) 1985-05-30

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