JPS57120586A - Dibenzazepine derivative, manufacture and use - Google Patents

Dibenzazepine derivative, manufacture and use

Info

Publication number
JPS57120586A
JPS57120586A JP56189374A JP18937481A JPS57120586A JP S57120586 A JPS57120586 A JP S57120586A JP 56189374 A JP56189374 A JP 56189374A JP 18937481 A JP18937481 A JP 18937481A JP S57120586 A JPS57120586 A JP S57120586A
Authority
JP
Japan
Prior art keywords
manufacture
dibenzazepine
derivative
dibenzazepine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56189374A
Other languages
English (en)
Japanese (ja)
Inventor
Miyuraa Buerunaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of JPS57120586A publication Critical patent/JPS57120586A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP56189374A 1980-11-28 1981-11-27 Dibenzazepine derivative, manufacture and use Pending JPS57120586A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH882980A CH646696A5 (de) 1980-11-28 1980-11-28 Dibenzazepine, ihre herstellung und verwendung.

Publications (1)

Publication Number Publication Date
JPS57120586A true JPS57120586A (en) 1982-07-27

Family

ID=4345211

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56189374A Pending JPS57120586A (en) 1980-11-28 1981-11-27 Dibenzazepine derivative, manufacture and use

Country Status (7)

Country Link
US (1) US4434171A (OSRAM)
JP (1) JPS57120586A (OSRAM)
CH (1) CH646696A5 (OSRAM)
DE (1) DE3145678A1 (OSRAM)
FR (1) FR2495153A1 (OSRAM)
GB (1) GB2088373B (OSRAM)
IT (1) IT1172093B (OSRAM)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5502047A (en) * 1993-03-22 1996-03-26 Kavey; Neil B. Treatment for insomnia
US5354747A (en) * 1993-06-16 1994-10-11 G. D. Searle & Co. 2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
US5461047A (en) * 1993-06-16 1995-10-24 G. D. Searle & Co. 2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
US20100227916A1 (en) * 2006-05-19 2010-09-09 Somaxon Pharmaceuticals, Inc N-desmethyl-doxepin and methods of using the same to treat sleep disorders
US20100179215A1 (en) 2006-05-19 2010-07-15 Somaxon Pharmaceuticals, Inc. Doxepin isomers and isomeric mixtures and methods of using the same to treat sleep disorders
US20090042971A1 (en) * 2006-05-19 2009-02-12 Somaxon Pharmaceuticals, Inc. Method of using low-dose doxepin for the improvement of sleep
US8513299B2 (en) 2006-05-19 2013-08-20 Pernix Sleep, Inc. Methods of using low-dose doxepin for the improvement of sleep
US20100179214A1 (en) * 2006-05-19 2010-07-15 Somaxon Pharmaceuticals, Inc. Doxepin trans isomers and isomeric mixtures and methods of using the same to treat sleep disorders
US20080058408A1 (en) * 2006-05-19 2008-03-06 Rogowski Roberta L Low-dose doxepin for treatment of sleep disorders in elderly patients
US20090042972A1 (en) * 2006-05-19 2009-02-12 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
CA2693992C (en) 2006-07-20 2017-01-31 Somaxon Pharmaceuticals, Inc. Methods of improving the pharmacokinetics of doxepin
WO2008085567A1 (en) * 2006-10-04 2008-07-17 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
WO2008052139A2 (en) 2006-10-25 2008-05-02 Somaxon Pharmaceuticals, Inc. Ultra low dose doxepin and methods of using the same to treat sleep disorders
US20110077200A1 (en) 2006-12-06 2011-03-31 Somaxon Pharmaceuticals, Inc. Combination therapy using low-dose doxepin for the improvement of sleep
WO2008128115A2 (en) 2007-04-13 2008-10-23 Somaxon Pharmaceuticals, Inc. Low-dose doxepin formulations
AU2021244215A1 (en) 2020-03-26 2022-10-13 Seagen Inc. Methods of treating multiple myeloma

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3153652A (en) 1964-10-20 Certificate of correction
US2802007A (en) 1954-05-24 1957-08-06 Lakeside Lab Inc Method of reducing 3-hydroxypyridine and its derivatives
DE1136706B (de) 1958-05-30 1962-09-20 Cilag Chemie Verfahren zur Herstellung von basisch substituierten, schwefelhaltigen 1-Aza-[2, 3:5, 6]-dibenzocycloheptadien-derivaten und deren Salzen
US3038896A (en) 1958-05-30 1962-06-12 Cilag Chemie 1-(di-lower alkyl amino lower alkyl thio lower alkyl)-aza-[2, 3:5, 6]-dibenzocycloheptadiene compounds
US3079394A (en) 1960-02-10 1963-02-26 Pittsburgh Plate Glass Co Novel chemical compound
GB1057145A (en) 1963-08-16 1967-02-01 Bellon Labor Sa Roger Phenylcyclohexylacetonitrile derivatives
US3928356A (en) 1967-10-06 1975-12-23 Fujisawa Pharmaceutical Co 10-{8 4-({107 -Hydroxy alkyl)-1-piperazimyl{9 -dibenzo (h,f) oxofins and thiepins and acetyl esters thereof
SE342045B (OSRAM) * 1967-12-27 1972-01-24 Yoshitomi Pharmaceutical
FR96408E (fr) 1968-10-08 1972-06-30 Saint Marcel Mfg Procédé de fabrication de chaussures ou éléments de chaussures constitués en tout ou partie par une matiere synthétique.
US3894001A (en) 1969-08-07 1975-07-08 Colgate Palmolive Co 11-Aminoalkyl- and 11-cyclicaminomorphanthridines
AR206937A1 (es) 1974-09-06 1976-08-31 Lilly Co Eli Procedimiento para preparar compuestos de 1-sustituido-4-alquil-4-fenil-piperidina
US4045445A (en) 1975-12-14 1977-08-30 American Cyanamid Company 11-(4-Piperidyl)dibenzo-diazepines
US4221715A (en) 1979-08-03 1980-09-09 American Cyanamid Company Substituted dibenz[b,f][1,4]oxazepin-11-yl pyridinium salts and derivatives thereof
FI803030A7 (fi) 1979-10-01 1981-01-01 Sandoz Ag Dibentsatsepiinijohdannaiset, niiden tuotanto ja niitä sisältävät farmaseuttiset yhdistelmät.

Also Published As

Publication number Publication date
FR2495153A1 (fr) 1982-06-04
FR2495153B1 (OSRAM) 1985-01-11
IT8149760A0 (it) 1981-11-24
US4434171A (en) 1984-02-28
DE3145678A1 (de) 1982-07-08
IT1172093B (it) 1987-06-18
GB2088373A (en) 1982-06-09
CH646696A5 (de) 1984-12-14
GB2088373B (en) 1984-09-19

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