JPS5711996A - Novel coenzyme a compound and its preparation - Google Patents

Novel coenzyme a compound and its preparation

Info

Publication number
JPS5711996A
JPS5711996A JP8592480A JP8592480A JPS5711996A JP S5711996 A JPS5711996 A JP S5711996A JP 8592480 A JP8592480 A JP 8592480A JP 8592480 A JP8592480 A JP 8592480A JP S5711996 A JPS5711996 A JP S5711996A
Authority
JP
Japan
Prior art keywords
formula
coenzyme
salt
compound
compound shown
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8592480A
Other languages
Japanese (ja)
Inventor
Sadao Tanaka
Isao Matsunaga
Shinichi Kamaike
Kiyoshige Wakabayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP8592480A priority Critical patent/JPS5711996A/en
Publication of JPS5711996A publication Critical patent/JPS5711996A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A coenzyme A compound shown by the formula I [R' is a group shown by the formula II or formula III (I* shows that iodine may be marked by a radioisotope) linked to the 2-, 6-, or 8-position of purine ring; R1 is amino or as shown for R'; R2 and R3 and H, phosphoric acid group, or form a group shown by the formula IV] or its salt.
EXAMPLE: A lithium salt of 8-(4-hydroxy-3-iodophenetilamino)-3'-dephospho coenzyme A.
USE: A diagnosticum for cancer. Diagnosis is carried out by determining the concentration of coenzyme A in humors.
PROCESS: A compound shown by the formula V or its salt is conventionally led to a reactive derivative, which is reacted with 4'-phosphopantetheine or its salt, to give a compound shown by the formula I.
COPYRIGHT: (C)1982,JPO&Japio
JP8592480A 1980-06-26 1980-06-26 Novel coenzyme a compound and its preparation Pending JPS5711996A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8592480A JPS5711996A (en) 1980-06-26 1980-06-26 Novel coenzyme a compound and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8592480A JPS5711996A (en) 1980-06-26 1980-06-26 Novel coenzyme a compound and its preparation

Publications (1)

Publication Number Publication Date
JPS5711996A true JPS5711996A (en) 1982-01-21

Family

ID=13872310

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8592480A Pending JPS5711996A (en) 1980-06-26 1980-06-26 Novel coenzyme a compound and its preparation

Country Status (1)

Country Link
JP (1) JPS5711996A (en)

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