JPS57106695A - Anthracycline g lycoside compound - Google Patents

Anthracycline g lycoside compound

Info

Publication number
JPS57106695A
JPS57106695A JP56172204A JP17220481A JPS57106695A JP S57106695 A JPS57106695 A JP S57106695A JP 56172204 A JP56172204 A JP 56172204A JP 17220481 A JP17220481 A JP 17220481A JP S57106695 A JPS57106695 A JP S57106695A
Authority
JP
Japan
Prior art keywords
hydrogen atom
anthracycline
lycoside
compound
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56172204A
Other languages
English (en)
Other versions
JPS634835B2 (ja
Inventor
Barujiotsuchi Aruberuto
Katsushineri Jiyuzetsupe
Penko Serujio
Arukamone Fuederiko
Kasatsuza Annamaria
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlo Erba SpA filed Critical Carlo Erba SpA
Publication of JPS57106695A publication Critical patent/JPS57106695A/ja
Publication of JPS634835B2 publication Critical patent/JPS634835B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP56172204A 1980-11-01 1981-10-29 Anthracycline g lycoside compound Granted JPS57106695A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8035204 1980-11-01

Publications (2)

Publication Number Publication Date
JPS57106695A true JPS57106695A (en) 1982-07-02
JPS634835B2 JPS634835B2 (ja) 1988-02-01

Family

ID=10517040

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56172204A Granted JPS57106695A (en) 1980-11-01 1981-10-29 Anthracycline g lycoside compound

Country Status (6)

Country Link
US (1) US4366149A (ja)
EP (1) EP0051280B1 (ja)
JP (1) JPS57106695A (ja)
AT (1) ATE8401T1 (ja)
CA (1) CA1174670A (ja)
DE (2) DE51280T1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01153694A (ja) * 1987-11-10 1989-06-15 Farmitalia Carlo Erba Spa 新規4‐デメトキシアントラサイクリン誘導体

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8508079D0 (en) * 1985-03-28 1985-05-01 Erba Farmitalia Antitumor anthracyclines
GB8614323D0 (en) * 1986-06-12 1986-07-16 Erba Farmitalia Anthracyclines
GB8708927D0 (en) * 1987-04-14 1987-05-20 Erba Farmitalia Chiral synthesis of anthracyclines
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB8803076D0 (en) * 1988-02-10 1988-03-09 Erba Carlo Spa 3'-deamino-4'-deoxy-4'-amino anthracyclines
DE3842836A1 (de) * 1988-12-20 1990-06-21 Behringwerke Ag Rhodomycine mit einer modifizierten kohlenhydrat-einheit
GB8902709D0 (en) * 1989-02-07 1989-03-30 Erba Carlo Spa New 4'-epi-4'-amino anthracyclines
US5412081A (en) * 1989-02-07 1995-05-02 Farmitalia Carlo Erba S.R.L. New 4'-epi-4'-amino anthracyclines
JPH0474764U (ja) * 1990-10-31 1992-06-30
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
WO2010066252A1 (en) 2008-12-09 2010-06-17 Dako Denmark A/S Method for evaluating pre-treatment
WO2010124689A1 (en) 2009-05-01 2010-11-04 Dako Denmark A/S New antibody cocktail

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1457632A (en) * 1974-03-22 1976-12-08 Farmaceutici Italia Adriamycins
US4020270A (en) * 1974-05-02 1977-04-26 Societa' Farmaceutici Italia S.P.A. L-lyxohex-1-enopyranose derivative
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
US4265885A (en) * 1978-10-25 1981-05-05 Farmitalia Carlo Erba S.P.A. Anthracyclines containing branched-chain amino-deoxy sugars

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01153694A (ja) * 1987-11-10 1989-06-15 Farmitalia Carlo Erba Spa 新規4‐デメトキシアントラサイクリン誘導体

Also Published As

Publication number Publication date
EP0051280B1 (en) 1984-07-11
EP0051280A1 (en) 1982-05-12
DE51280T1 (de) 1983-01-20
ATE8401T1 (de) 1984-07-15
CA1174670A (en) 1984-09-18
JPS634835B2 (ja) 1988-02-01
DE3164763D1 (en) 1984-08-16
US4366149A (en) 1982-12-28

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