JPS57105423A - Chloroethylureidopropylpolysilsesquioxane - Google Patents
ChloroethylureidopropylpolysilsesquioxaneInfo
- Publication number
- JPS57105423A JPS57105423A JP18140880A JP18140880A JPS57105423A JP S57105423 A JPS57105423 A JP S57105423A JP 18140880 A JP18140880 A JP 18140880A JP 18140880 A JP18140880 A JP 18140880A JP S57105423 A JPS57105423 A JP S57105423A
- Authority
- JP
- Japan
- Prior art keywords
- chloroethylureido
- propyltriethoxysilane
- structural units
- expressed
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: The titled compound, consisting of specific structural units, obtained by hydrolyzing 3-(β-chloroethylureido)propyltriethoxysilane, etc., relatively stable to acids and alkalis, and suitable for a carcinostatic agent.
CONSTITUTION: 3-( β-chloroethylureido )propyltriethoxysilane expressed by formulaIis hydrolyzed and condensed preferably at 0W80°C for 1W60hr to give the aimed compound consisting of structural units expressed by formula II. The resultant compound has remarkably improved physiological activity compared with other polysilsesquioxanes, and exhibits improved effects particularly on the carcinostatic activity with relatively mild toxicity and suitably usable for the prevention, remedy and treatment of various cancers. The form of use is any one of the oral, parenteral or local administration, and the effective dose thereof is 50W0.02mg/kg/day. The active constituent concentration is preferably 1W60wt%.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18140880A JPS57105423A (en) | 1980-12-23 | 1980-12-23 | Chloroethylureidopropylpolysilsesquioxane |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18140880A JPS57105423A (en) | 1980-12-23 | 1980-12-23 | Chloroethylureidopropylpolysilsesquioxane |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP272784A Division JPS59144792A (en) | 1984-01-12 | 1984-01-12 | 3-(beta-chloroethylureide)propyl triethoxy silane |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57105423A true JPS57105423A (en) | 1982-06-30 |
JPS6147165B2 JPS6147165B2 (en) | 1986-10-17 |
Family
ID=16100231
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP18140880A Granted JPS57105423A (en) | 1980-12-23 | 1980-12-23 | Chloroethylureidopropylpolysilsesquioxane |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57105423A (en) |
-
1980
- 1980-12-23 JP JP18140880A patent/JPS57105423A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6147165B2 (en) | 1986-10-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS53113008A (en) | Constant rate releasing preparation | |
JPS5551020A (en) | Remedy for rheumatism | |
FI955837A0 (en) | Process for the preparation of an orally administrable solid dosage form containing diclofenac | |
JPS57109721A (en) | Carcinostatic agent | |
JPS57105423A (en) | Chloroethylureidopropylpolysilsesquioxane | |
JPS55122715A (en) | Antidiabetic agent | |
JPS57114512A (en) | Antidia beticagent comprising (3-dimethyl-carbamoxy- phenyl)trimethyl ammonium derivative | |
JPS56115715A (en) | Physiologically active agent containing (3- dimethylcarbam-oxyphenyl) trimethyl ammonium derivative | |
JPS5634626A (en) | Anti-inflammatory | |
JPS5742620A (en) | Novel antiulcer agent | |
JPS5551018A (en) | Carcinostatic agent | |
JPS5639019A (en) | Antiviral agent | |
JPS5498339A (en) | Carcinostatic agent | |
JPS57114519A (en) | Antiarteriosclerotic agent | |
JPS5675432A (en) | Antitumor agent containing ethyl piperidylacetylaminobenzoate | |
JPS53130496A (en) | Preparation of polysaccharides | |
JPS5634624A (en) | Central nervous system depressant | |
JPS57128625A (en) | Carcinostatic | |
JPS57114518A (en) | Hypotensive agent | |
JPS57114513A (en) | Drug against arterioscleriosis comprising (3-dimethylca- rbamoxyphenyl)trimethyl ammonium derivative | |
JPS5634625A (en) | Antitumorigenic agent | |
JPS55122719A (en) | Medicine composition having antipyretic, analgesic, and anti-inflammatory action | |
JPS5675427A (en) | Antiarteriosclerotic agent containing procainamide hydrochloride | |
JPS5759809A (en) | Cardiotonic agent | |
JPS57114514A (en) | Antiphlogistic comprising (3-dimethylcarbamoxyphenyl) trimethyl ammonium derivative |