JPS5686139A - P-hydroxyphenylglycine o-toluenesulfonate - Google Patents
P-hydroxyphenylglycine o-toluenesulfonateInfo
- Publication number
- JPS5686139A JPS5686139A JP14015180A JP14015180A JPS5686139A JP S5686139 A JPS5686139 A JP S5686139A JP 14015180 A JP14015180 A JP 14015180A JP 14015180 A JP14015180 A JP 14015180A JP S5686139 A JPS5686139 A JP S5686139A
- Authority
- JP
- Japan
- Prior art keywords
- hydroxyphenylglycine
- toluenesulfonate
- optical
- compound
- neutralized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:p-Hydroxyphenylglycine o-toluenesulfonate.
USE: A salt undergoing preferential crystallization to give optical active p-hydroxyphenylglycine useful as a raw material for a semisynthetic penicillin derivative and a semisynthetic cephalosporin derivative. The salt has properties necessary for optical resolution, racemic modification being more soluble than the optical active compound, the super saturated state of the optical compound being stable, etc.
PROCESS: Free-hydroxyphenylglycine is neutralized with o-toluenesulfonic acid in a solvent, and the neutralized compound is crystallized by conventional means, e.g., concentration, cooling, etc. to give DL-p-hydroxyphenylglycine o-toluenesulfonate.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14015180A JPS5686139A (en) | 1980-10-06 | 1980-10-06 | P-hydroxyphenylglycine o-toluenesulfonate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14015180A JPS5686139A (en) | 1980-10-06 | 1980-10-06 | P-hydroxyphenylglycine o-toluenesulfonate |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP334576A Division JPS5287137A (en) | 1976-01-13 | 1976-01-13 | Production of optically active p-hydroxyphenylglycine |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5686139A true JPS5686139A (en) | 1981-07-13 |
JPS5648501B2 JPS5648501B2 (en) | 1981-11-16 |
Family
ID=15262049
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14015180A Granted JPS5686139A (en) | 1980-10-06 | 1980-10-06 | P-hydroxyphenylglycine o-toluenesulfonate |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5686139A (en) |
-
1980
- 1980-10-06 JP JP14015180A patent/JPS5686139A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS5648501B2 (en) | 1981-11-16 |
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