JPS5681595A - Moranoline derivative and its preparation - Google Patents
Moranoline derivative and its preparationInfo
- Publication number
- JPS5681595A JPS5681595A JP15941779A JP15941779A JPS5681595A JP S5681595 A JPS5681595 A JP S5681595A JP 15941779 A JP15941779 A JP 15941779A JP 15941779 A JP15941779 A JP 15941779A JP S5681595 A JPS5681595 A JP S5681595A
- Authority
- JP
- Japan
- Prior art keywords
- moranoline
- cyclodextrin
- passed
- formula
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Hydrogenated Pyridines (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:An oligoglucosymoranoline expressed by formula I (n is an integer 0W3).
EXAMPLE: 4-(α-D-Maltotetraosyl)-moranoline.
USE: A suppersant against hyperglycemia.
PROCESS: A mixed solution of moranoline of formula II with cyclodextrin of soluble starch is reacted with cyclodextrin glycosytransferase preferably at 40°C and pH 5.0W8.5 for 1W3 days. The reaction solution is then passed through a strongly acidic ion exchange resin column to adsorb a basic substance on the resin, and the adsorbed substance is eluted wirh 0.5N. aqueous ammonia. The eluate is then concentrated in vacuo and passed through a Sephadex column to collect a desired fraction.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15941779A JPS5681595A (en) | 1979-12-08 | 1979-12-08 | Moranoline derivative and its preparation |
GB8037691A GB2064527B (en) | 1979-12-08 | 1980-11-25 | Moranoline derivatives and process for preparation thereof |
FR8025953A FR2471387A1 (en) | 1979-12-08 | 1980-12-05 | PROCESS FOR THE PREPARATION OF MORANOLINE DERIVATIVES, NOVEL PRODUCTS THUS OBTAINED AND THEIR USE FOR CONTROLLING THE INCREASE IN SUGAR LEVELS IN BLOOD |
IT50321/80A IT1188970B (en) | 1979-12-08 | 1980-12-05 | MORANOLINA DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION |
CH9050/80A CH649302A5 (en) | 1979-12-08 | 1980-12-08 | MORANOLINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF. |
DE19803046184 DE3046184A1 (en) | 1979-12-08 | 1980-12-08 | "MORANOLINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF" |
US06/214,009 US4338433A (en) | 1979-12-08 | 1980-12-08 | Moranoline derivatives and process for preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15941779A JPS5681595A (en) | 1979-12-08 | 1979-12-08 | Moranoline derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5681595A true JPS5681595A (en) | 1981-07-03 |
JPS612076B2 JPS612076B2 (en) | 1986-01-22 |
Family
ID=15693284
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15941779A Granted JPS5681595A (en) | 1979-12-08 | 1979-12-08 | Moranoline derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5681595A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3712799A1 (en) * | 1986-04-15 | 1987-10-22 | Nippon Shinyaku Co Ltd | METHOD FOR PRODUCING MORANOLINE DERIVATIVES |
DE3712818A1 (en) * | 1986-04-15 | 1987-10-22 | Nippon Shinyaku Co Ltd | METHOD FOR PRODUCING MORANOLINE DERIVATIVES |
WO1993017100A1 (en) * | 1992-02-21 | 1993-09-02 | Nippon Shinyaku Co., Ltd. | Specific adsorbent and purification method |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH052691U (en) * | 1991-05-08 | 1993-01-19 | 成行 拝原 | Pickles |
-
1979
- 1979-12-08 JP JP15941779A patent/JPS5681595A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3712799A1 (en) * | 1986-04-15 | 1987-10-22 | Nippon Shinyaku Co Ltd | METHOD FOR PRODUCING MORANOLINE DERIVATIVES |
DE3712818A1 (en) * | 1986-04-15 | 1987-10-22 | Nippon Shinyaku Co Ltd | METHOD FOR PRODUCING MORANOLINE DERIVATIVES |
WO1993017100A1 (en) * | 1992-02-21 | 1993-09-02 | Nippon Shinyaku Co., Ltd. | Specific adsorbent and purification method |
Also Published As
Publication number | Publication date |
---|---|
JPS612076B2 (en) | 1986-01-22 |
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