JPS5681533A - Preparation of 4-hydroxyphenyl acetic acids - Google Patents

Preparation of 4-hydroxyphenyl acetic acids

Info

Publication number
JPS5681533A
JPS5681533A JP15747179A JP15747179A JPS5681533A JP S5681533 A JPS5681533 A JP S5681533A JP 15747179 A JP15747179 A JP 15747179A JP 15747179 A JP15747179 A JP 15747179A JP S5681533 A JPS5681533 A JP S5681533A
Authority
JP
Japan
Prior art keywords
palladium catalyst
formula
compound shown
cocatalyst
zinc acetate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15747179A
Other languages
Japanese (ja)
Other versions
JPS6126976B2 (en
Inventor
Yoshio Umemura
Fumio Iwata
Takuji Enomiya
Takahito Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ube Corp
Original Assignee
Ube Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries Ltd filed Critical Ube Industries Ltd
Priority to JP15747179A priority Critical patent/JPS5681533A/en
Publication of JPS5681533A publication Critical patent/JPS5681533A/en
Publication of JPS6126976B2 publication Critical patent/JPS6126976B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PURPOSE: To obtain the titled substance useful as an intermediate for a drug in high reactivity and in high yield without problems of the corrosion of device, etc., by reducing 4-hydroxymandelic acids with hydrogen in water in the presence of a palladium catalyst and a cocatalyst of zinc acetate.
CONSTITUTION: A compound shown by the formula I (X is H or halogen) is reduced with hydrogen in water in the presence of a palladium catalyst and a cocatalyst of zinc acetate, to give a compound shown by the formula II (especially X is H or Cl). A palladium catalyst wherein 0.5W8wt% metal palladium is supported on a carrier. e.g., active carbon, graphite, etc. is suitable as the palladium catalyst, and its amount is 0.01W0.5g calculated as metal palladium based on 1mol compound shown by the formula I. The cocatalyst of zinc acetate may be supported on the carrier together with the palladium catalyst, and its amount is 0.02W0.1mol based on 1mol compound shown by the formula I. The addition of a small amount of an acid, e.g., hydrochloric acid, sulfuric acid, etc. to the reaction system improves the reaction rate.
COPYRIGHT: (C)1981,JPO&Japio
JP15747179A 1979-12-06 1979-12-06 Preparation of 4-hydroxyphenyl acetic acids Granted JPS5681533A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15747179A JPS5681533A (en) 1979-12-06 1979-12-06 Preparation of 4-hydroxyphenyl acetic acids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15747179A JPS5681533A (en) 1979-12-06 1979-12-06 Preparation of 4-hydroxyphenyl acetic acids

Publications (2)

Publication Number Publication Date
JPS5681533A true JPS5681533A (en) 1981-07-03
JPS6126976B2 JPS6126976B2 (en) 1986-06-23

Family

ID=15650393

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15747179A Granted JPS5681533A (en) 1979-12-06 1979-12-06 Preparation of 4-hydroxyphenyl acetic acids

Country Status (1)

Country Link
JP (1) JPS5681533A (en)

Also Published As

Publication number Publication date
JPS6126976B2 (en) 1986-06-23

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