JPS5663967A - Novel quinazoline derivative - Google Patents
Novel quinazoline derivativeInfo
- Publication number
- JPS5663967A JPS5663967A JP13872779A JP13872779A JPS5663967A JP S5663967 A JPS5663967 A JP S5663967A JP 13872779 A JP13872779 A JP 13872779A JP 13872779 A JP13872779 A JP 13872779A JP S5663967 A JPS5663967 A JP S5663967A
- Authority
- JP
- Japan
- Prior art keywords
- dimethoxyquinazoline
- amino
- quinazoline derivative
- formula
- novel quinazoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound expressed by formula I (R is 3W7C cycloalkyl, furyl, tetrahydrofuryl or tetrahydropyranyl; X is O or S; n is 2 or 3) or a pharmaceutically acceptable acid addition salt thereof.
EXAMPLE: 2-( 4-Cyclopropylcarbamoyl- piperazin-1-yl )-4-amino-6, 7-dimethoxyquinazoline.
USE: A hypotensive agent.
PROCESS: 2-(Piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline of formula II or 2- (homopiperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline II is reacted with an isocyanate or isothiocyanate of formula III.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13872779A JPS5663967A (en) | 1979-10-29 | 1979-10-29 | Novel quinazoline derivative |
US06/199,565 US4607034A (en) | 1979-10-29 | 1980-10-21 | Quinazoline derivatives and pharmaceutical composition thereof |
CA000363320A CA1141378A (en) | 1979-10-29 | 1980-10-27 | Quinazoline derivatives |
EP80106648A EP0028031B1 (en) | 1979-10-29 | 1980-10-29 | Novel quinazoline derivatives, a pharmaceutical composition containing such derivatives as active ingredient and a process for producing the quinazoline derivatives |
DE8080106648T DE3064773D1 (en) | 1979-10-29 | 1980-10-29 | Novel quinazoline derivatives, a pharmaceutical composition containing such derivatives as active ingredient and a process for producing the quinazoline derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13872779A JPS5663967A (en) | 1979-10-29 | 1979-10-29 | Novel quinazoline derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5663967A true JPS5663967A (en) | 1981-05-30 |
JPS6313991B2 JPS6313991B2 (en) | 1988-03-29 |
Family
ID=15228737
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13872779A Granted JPS5663967A (en) | 1979-10-29 | 1979-10-29 | Novel quinazoline derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5663967A (en) |
-
1979
- 1979-10-29 JP JP13872779A patent/JPS5663967A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6313991B2 (en) | 1988-03-29 |
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