JPS565473A - Spiro compound and its preparation - Google Patents

Spiro compound and its preparation

Info

Publication number
JPS565473A
JPS565473A JP8055179A JP8055179A JPS565473A JP S565473 A JPS565473 A JP S565473A JP 8055179 A JP8055179 A JP 8055179A JP 8055179 A JP8055179 A JP 8055179A JP S565473 A JPS565473 A JP S565473A
Authority
JP
Japan
Prior art keywords
formula
compound
ring
spiro compound
gastric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8055179A
Other languages
Japanese (ja)
Other versions
JPS5931511B2 (en
Inventor
Hirosada Sugihara
Masazumi Watanabe
Mitsuru Kawada
Isuke Imada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP8055179A priority Critical patent/JPS5931511B2/en
Priority to US06/115,548 priority patent/US4284644A/en
Priority to GR61757A priority patent/GR66729B/el
Priority to DK184680A priority patent/DK153551C/en
Priority to AU57903/80A priority patent/AU534940B2/en
Priority to HU107480A priority patent/HU184914B/en
Priority to EP80301431A priority patent/EP0018830B1/en
Priority to DE8181104398T priority patent/DE3067491D1/en
Priority to EP81104399A priority patent/EP0039091B1/en
Priority to DE8181104399T priority patent/DE3068085D1/en
Priority to DE8080301431T priority patent/DE3063660D1/en
Priority to CA000351051A priority patent/CA1150287A/en
Priority to EP81104398A priority patent/EP0038576B1/en
Priority to AT470181A priority patent/AT380018B/en
Priority to NO801290A priority patent/NO155053C/en
Priority to AT0233880A priority patent/AT383122B/en
Priority to ES491150A priority patent/ES491150A0/en
Priority to SU802917050A priority patent/SU1022658A3/en
Priority to ES497669A priority patent/ES8205405A1/en
Publication of JPS565473A publication Critical patent/JPS565473A/en
Priority to US06/257,316 priority patent/US4342779A/en
Priority to ES502179A priority patent/ES502179A0/en
Priority to ES502178A priority patent/ES502178A0/en
Priority to NO811788A priority patent/NO154839C/en
Priority to NO811787A priority patent/NO154838C/en
Priority to DK344881A priority patent/DK344881A/en
Priority to DK344781A priority patent/DK344781A/en
Priority to CA000394405A priority patent/CA1138469A/en
Priority to CA000394406A priority patent/CA1140562A/en
Priority to AT376683A priority patent/AT381938B/en
Publication of JPS5931511B2 publication Critical patent/JPS5931511B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

NEW MATERIAL:A spiro compound of formula I [ring A is benzene or naphthalen ring each having one or more substituents [lower alkyl, NO2, halogen, acyl, SO2NH2, COOH, lower alkoxycarbonyl, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, CN, phenyl, or amino, hydroxyl, carbamoyl, ureido, thioureido or aminomethyl which may have a substitutent]].
EXAMPLE: Spino[benzo[b]furan-2(3H),1'-cyclopropan]-3-one.
USE: A gastric secretion suppressant anti-inflammatory agent or analgesic agent, e.g. a remedy for gastric or duodenal ulcer, acute or chronic gastritis, lumbago or arthritis, and an intermediate for the agents.
PROCESS: A compound of formula II is decarboxylated in the presence of a catalyst, e.g. a metal halide, to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP8055179A 1977-01-12 1979-06-25 Spiro compounds and their production methods Expired JPS5931511B2 (en)

Priority Applications (29)

Application Number Priority Date Filing Date Title
JP8055179A JPS5931511B2 (en) 1979-06-25 1979-06-25 Spiro compounds and their production methods
US06/115,548 US4284644A (en) 1977-01-12 1980-01-25 Spirobenzofuranone compounds
GR61757A GR66729B (en) 1979-05-04 1980-04-23
DK184680A DK153551C (en) 1979-05-04 1980-04-29 METHOD OF ANALOGY FOR THE PREPARATION OF SPIROBENZOFURANONE COMPOUNDS OR SALTS THEREOF WITH INORGANIC OR ORGANIC ACIDS OR ALKALIMETALS
AU57903/80A AU534940B2 (en) 1979-05-04 1980-04-30 Spirobenzofuranones
HU107480A HU184914B (en) 1979-06-25 1980-04-30 Process for preparing spirobenzofuranones and pharmaceutical compositions containing such compounds as active substances
EP80301431A EP0018830B1 (en) 1979-05-04 1980-05-01 Spirobenzofuranones, their production and pharmaceutical compositions containing them
DE8181104398T DE3067491D1 (en) 1979-05-04 1980-05-01 7-ACETYL SPIROBENZOFURANONE COMPOUND
EP81104399A EP0039091B1 (en) 1979-05-04 1980-05-01 Spirobenzofuranone compounds
DE8181104399T DE3068085D1 (en) 1979-05-04 1980-05-01 SPIROBENZOFURANONE COMPOUNDS
DE8080301431T DE3063660D1 (en) 1979-05-04 1980-05-01 Spirobenzofuranones, their production and pharmaceutical compositions containing them
CA000351051A CA1150287A (en) 1979-05-04 1980-05-01 Spirobenzofuranones, their production and use
EP81104398A EP0038576B1 (en) 1979-05-04 1980-05-01 7-acetylspirobenzofuranone compound
NO801290A NO155053C (en) 1979-05-04 1980-05-02 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE SPIROBENZOFURANON COMPOUNDS.
AT0233880A AT383122B (en) 1979-05-04 1980-05-02 METHOD FOR PRODUCING NEW SPIROBENZOFURANONE COMPOUNDS
AT470181A AT380018B (en) 1979-05-04 1980-05-02 METHOD FOR PRODUCING THE NEW 7-ACETYL SPIRO (BENZO (B) FURAN-2 (3H), 1'-CYCLOPROPAN) -3-ONS
ES491150A ES491150A0 (en) 1979-05-04 1980-05-03 A PROCEDURE FOR PRODUCING SPIROBENZOFU-RANONA COMPOUNDS
SU802917050A SU1022658A3 (en) 1979-05-04 1980-05-05 Method of producing spirobenzofurans
ES497669A ES8205405A1 (en) 1979-05-04 1980-12-12 Spirobenzofuranones, their production and pharmaceutical compositions containing them.
US06/257,316 US4342779A (en) 1977-12-27 1981-04-17 7-Acetylspirobenzofuranone compound
ES502179A ES502179A0 (en) 1979-05-04 1981-05-13 A PROCEDURE FOR OBTAINING 7-ACETYLESPIRE (BENZO (B) FURAN-2 (3H) -1'-CYCLOPROPANE) -3-ONA
ES502178A ES502178A0 (en) 1979-05-04 1981-05-13 A PROCEDURE FOR OBTAINING A SPIROBENZOFU-RANONA COMPOUND
NO811788A NO154839C (en) 1979-05-04 1981-05-26 ANALOGUE PROCEDURE FOR PREPARING A 7-ACETYL PIROBENZOFURANONE COMPOUND WITH THERAPEUTIC ACTIVITY.
NO811787A NO154838C (en) 1979-05-04 1981-05-26 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE SPIROBENZOFURANON COMPOUNDS.
DK344881A DK344881A (en) 1979-05-04 1981-08-03 METHOD FOR PREPARING 7-ACETYLPIRO (BENZO (B) FURAN-2 (3H), 1! -CYCLOPROPAN) -3-ON.
DK344781A DK344781A (en) 1979-05-04 1981-08-03 PROCEDURE FOR PREPARING SPIROBENZOFURANONE COMPOUNDS
CA000394405A CA1138469A (en) 1979-05-04 1982-01-18 Spirobenzofuranones, their production and use
CA000394406A CA1140562A (en) 1979-05-04 1982-01-18 Spirobenzofuranones, their production and use
AT376683A AT381938B (en) 1979-06-25 1983-10-24 METHOD FOR PRODUCING NEW SPIROBENZOFURANONE COMPOUNDS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8055179A JPS5931511B2 (en) 1979-06-25 1979-06-25 Spiro compounds and their production methods

Publications (2)

Publication Number Publication Date
JPS565473A true JPS565473A (en) 1981-01-20
JPS5931511B2 JPS5931511B2 (en) 1984-08-02

Family

ID=13721471

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8055179A Expired JPS5931511B2 (en) 1977-01-12 1979-06-25 Spiro compounds and their production methods

Country Status (2)

Country Link
JP (1) JPS5931511B2 (en)
HU (1) HU184914B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10375386B2 (en) 2017-06-07 2019-08-06 Panasonic Intellectual Property Management Co., Ltd. Calibration device, calibration method, and program for projection display device, projection display device, and projection display system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10375386B2 (en) 2017-06-07 2019-08-06 Panasonic Intellectual Property Management Co., Ltd. Calibration device, calibration method, and program for projection display device, projection display device, and projection display system

Also Published As

Publication number Publication date
HU184914B (en) 1984-11-28
JPS5931511B2 (en) 1984-08-02

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