JPS56500655A - - Google Patents
Info
- Publication number
- JPS56500655A JPS56500655A JP50123580A JP50123580A JPS56500655A JP S56500655 A JPS56500655 A JP S56500655A JP 50123580 A JP50123580 A JP 50123580A JP 50123580 A JP50123580 A JP 50123580A JP S56500655 A JPS56500655 A JP S56500655A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
- 
        - C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57581—Thymosin; Related peptides
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
 
- 
        - Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/18—Thymus derived hormone or factor; related peptides
 
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| DE19792919592 DE2919592A1 (de) | 1979-05-15 | 1979-05-15 | Verfahren zur herstellung von thymosin- alpha 1 und derivaten davon | 
Publications (2)
| Publication Number | Publication Date | 
|---|---|
| JPS56500655A true JPS56500655A (OSRAM) | 1981-05-14 | 
| JPH0135840B2 JPH0135840B2 (OSRAM) | 1989-07-27 | 
Family
ID=6070778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| JP55501235A Expired JPH0135840B2 (OSRAM) | 1979-05-15 | 1980-05-14 | 
Country Status (8)
| Country | Link | 
|---|---|
| US (2) | US4353821A (OSRAM) | 
| EP (1) | EP0028627B1 (OSRAM) | 
| JP (1) | JPH0135840B2 (OSRAM) | 
| CH (1) | CH649089A5 (OSRAM) | 
| DE (1) | DE2919592A1 (OSRAM) | 
| GB (1) | GB2065662B (OSRAM) | 
| NL (1) | NL8020195A (OSRAM) | 
| WO (1) | WO1980002560A1 (OSRAM) | 
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| EP0033384B1 (de) * | 1980-01-18 | 1984-02-15 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Thymosin-alpha-1-Fragmente enthaltende Arzneimittel mit immunstimulierender Wirkung, und Thymosin-alpha-1-Fragmente | 
| DE3137231A1 (de) * | 1981-09-18 | 1983-04-14 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Bis-thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-verbindungen | 
| US4497801A (en) * | 1982-09-17 | 1985-02-05 | Fujisawa Pharmaceutical Co., Ltd. | New peptides, process for preparation thereof and use thereof | 
| US4581168A (en) * | 1983-02-21 | 1986-04-08 | Sanofi | Synthesis of hpGRF (Somatocrinin) in liquid phase and intermediate peptides | 
| US4517119A (en) * | 1983-04-04 | 1985-05-14 | Hoffmann-La Roche Inc. | Synthesis of thymosin α1 | 
| US4504415A (en) * | 1983-04-04 | 1985-03-12 | Hoffman-La Roche Inc. | Synthesis of thymosin α1 and desacetyl thymosin α1 | 
| FR2551088B1 (OSRAM) * | 1983-08-29 | 1985-12-06 | Pasteur Institut | |
| US4983387A (en) * | 1986-05-19 | 1991-01-08 | Viral Technologies Inc. | HIV related peptides, immunogenic antigens, and use therefor as subunit vaccine for AIDS virus | 
| ZA873215B (en) * | 1986-05-19 | 1987-10-28 | Viral Technologies Inc. | Htlv-iii/lav virus related peptides,antibodies to the peptides,vaccines,passive and active immunization against aids virus and diagnostic test for the serological detection of aids virus | 
| US5807830A (en) * | 1987-12-30 | 1998-09-15 | Cytoven J.V. | Method for treatment of purulent inflammatory diseases | 
| US5728680A (en) | 1987-12-30 | 1998-03-17 | Cytoven J.V. | Methods for normalizing numbers of lymphocytes | 
| US5811399A (en) * | 1988-12-14 | 1998-09-22 | Cytran, Inc. | Pharmaceutical dipeptide compositions and methods of use thereof: immunodepressants | 
| US5770576A (en) * | 1989-08-30 | 1998-06-23 | Cytran, Inc. | Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity | 
| US6066622A (en) | 1991-10-28 | 2000-05-23 | Cytran, Inc. | Immunomodulating peptides and methods of use | 
| US6100380A (en) * | 1991-10-28 | 2000-08-08 | Cytran, Inc. | Immunomodulating peptides and methods of use | 
| CN1058500C (zh) * | 1993-02-03 | 2000-11-15 | 施塞克龙药品公司 | 胸腺素α-1衍生物 | 
| AU6359594A (en) * | 1993-03-04 | 1994-09-26 | Cytoven International N.V. | Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof | 
| US6262230B1 (en) * | 1994-01-28 | 2001-07-17 | Sciclone Pharmaceuticals Inc. | Analogs of thymosin α1 | 
| US5632983A (en) | 1994-11-17 | 1997-05-27 | University Of South Florida | Method for treating secondary immunodeficiency | 
| AU2001268326A1 (en) * | 2000-06-14 | 2001-12-24 | Chanda Zaveri | Peptides with physiological activity | 
| US20070031372A1 (en) * | 2004-08-05 | 2007-02-08 | Hadden John W | Vaccine immunotherapy for immune suppressed patients | 
| US20070154399A1 (en) * | 2000-10-27 | 2007-07-05 | Hadden John W | Immunotherapy for immune suppressed patients | 
| US20060194242A1 (en) * | 2000-10-27 | 2006-08-31 | Hadden John W | Immunotherapy for immune suppressed patients | 
| US7182942B2 (en) * | 2000-10-27 | 2007-02-27 | Irx Therapeutics, Inc. | Vaccine immunotherapy for immune suppressed patients | 
| US20070025958A1 (en) * | 2000-10-27 | 2007-02-01 | Hadden John W | Vaccine immunotherapy | 
| EP1337149A4 (en) | 2000-10-27 | 2005-10-12 | Irx Therapeutics Inc | VACCINE IMMUNOTHERAPY FOR IMMUNE-PATIENT PATIENTS | 
| US20050020495A1 (en) * | 2001-10-24 | 2005-01-27 | Martins Eduardo Bruno Guimaraes | Antiretroviral compositions comprising thymosin alpha peptides and protease inhibitors | 
| JP2005510491A (ja) * | 2001-10-26 | 2005-04-21 | イミュノ−アールエックス, インコーポレイテッド | 免疫抑制を逆転させるための免疫治療 | 
| CN1269524C (zh) * | 2001-10-26 | 2006-08-16 | 罗得岛医院 | 胸腺素强化的遗传免疫方法 | 
| UA78726C2 (en) * | 2001-11-01 | 2007-04-25 | Sciclone Pharmaceuticals Inc | Pharmaceutical composition of thymosin alpha 1 conjugated with polyethylene glycol, method for production, and method for treatment | 
| UA77999C2 (en) * | 2001-12-10 | 2007-02-15 | Thymosin-alpha 1 for treatment of malignant glioblastoma | |
| CN100501400C (zh) | 2002-11-25 | 2009-06-17 | 希克龙制药公司 | 使用α胸腺素防护辐射损伤的方法 | 
| UA80870C2 (en) * | 2003-03-28 | 2007-11-12 | Sciclone Pharmaceuticals Inc | Method for treatment or prevention of aspergillus infections with thymosin alpha 1 | 
| US20100311656A1 (en) * | 2003-04-23 | 2010-12-09 | Sciclone Pharmaceuticals, Inc. | Treatment or prevention of respiratory viral infections with alpha thymosin peptides | 
| MXPA06000517A (es) * | 2003-07-18 | 2006-07-10 | Regenerx Biopharmaceuticals | Composiciones y metodos para el tratamiento o prevencion de dano debido a la exposicion a radiacion. | 
| WO2009070639A1 (en) | 2007-11-28 | 2009-06-04 | Irx Therapeutics, Inc. | Method of increasing immunological effect | 
| ES2679043T3 (es) | 2009-05-15 | 2018-08-21 | Irx Therapeutics, Inc. | Inmunoterapia de vacuna | 
| CN107050430B (zh) | 2009-12-08 | 2021-10-15 | 伊尔克斯治疗有限公司 | 逆转朗格汉斯细胞免疫抑制的方法 | 
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| JPS53137914A (en) * | 1977-04-22 | 1978-12-01 | Hoffmann La Roche | Thymocine alpha1 or asn2 homologue thereof | 
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| US4079127A (en) * | 1976-10-28 | 1978-03-14 | Board Of Regents Of The University Of Texas | Thymosin alpha 1 | 
| CH633258A5 (en) * | 1976-10-28 | 1982-11-30 | Hoffmann La Roche | Process for preparing thymosin alpha 1 | 
| US4116951A (en) * | 1977-04-22 | 1978-09-26 | Hoffmann-La Roche Inc. | [Asn2 ]-thymosin α1 and analogs thereof | 
| US4148788A (en) * | 1978-01-23 | 1979-04-10 | Hoffmann-La Roche Inc. | Synthesis of thymosin α1 | 
| DE2830442A1 (de) * | 1978-07-11 | 1980-01-24 | Max Planck Gesellschaft | Verfahren zur herstellung von polypeptiden | 
- 
        1979
        - 1979-05-15 DE DE19792919592 patent/DE2919592A1/de active Granted
 
- 
        1980
        - 1980-03-24 US US06/133,031 patent/US4353821A/en not_active Expired - Lifetime
- 1980-05-14 NL NL8020195A patent/NL8020195A/nl not_active Application Discontinuation
- 1980-05-14 GB GB8038854A patent/GB2065662B/en not_active Expired
- 1980-05-14 JP JP55501235A patent/JPH0135840B2/ja not_active Expired
- 1980-05-14 CH CH230/81A patent/CH649089A5/de not_active IP Right Cessation
- 1980-05-14 WO PCT/DE1980/000067 patent/WO1980002560A1/de active IP Right Grant
- 1980-12-01 EP EP80901003A patent/EP0028627B1/de not_active Expired
 
- 
        1982
        - 1982-07-29 US US06/403,218 patent/US4466918A/en not_active Expired - Fee Related
 
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| JPS53137914A (en) * | 1977-04-22 | 1978-12-01 | Hoffmann La Roche | Thymocine alpha1 or asn2 homologue thereof | 
Also Published As
| Publication number | Publication date | 
|---|---|
| JPH0135840B2 (OSRAM) | 1989-07-27 | 
| WO1980002560A1 (en) | 1980-11-27 | 
| CH649089A5 (de) | 1985-04-30 | 
| US4466918A (en) | 1984-08-21 | 
| GB2065662A (en) | 1981-07-01 | 
| US4353821A (en) | 1982-10-12 | 
| NL8020195A (nl) | 1981-02-27 | 
| EP0028627A1 (de) | 1981-05-20 | 
| GB2065662B (en) | 1983-03-30 | 
| DE2919592A1 (de) | 1981-01-15 | 
| DE2919592C2 (OSRAM) | 1992-01-16 | 
| EP0028627B1 (de) | 1984-05-09 |