JPS5645414A - Phosphodiesterase inhibitor - Google Patents
Phosphodiesterase inhibitorInfo
- Publication number
- JPS5645414A JPS5645414A JP12126279A JP12126279A JPS5645414A JP S5645414 A JPS5645414 A JP S5645414A JP 12126279 A JP12126279 A JP 12126279A JP 12126279 A JP12126279 A JP 12126279A JP S5645414 A JPS5645414 A JP S5645414A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- remedying
- derivative
- phosphodiesterase inhibitor
- phosphodiesterase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940099471 Phosphodiesterase inhibitor Drugs 0.000 title 1
- 239000002571 phosphodiesterase inhibitor Substances 0.000 title 1
- 208000006673 asthma Diseases 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 201000009961 allergic asthma Diseases 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 125000005606 carbostyryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 238000006704 dehydrohalogenation reaction Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 125000002572 propoxy group Chemical group [*]OC([H])([H])C(C([H])([H])[H])([H])[H] 0.000 abstract 1
- 208000020016 psychiatric disease Diseases 0.000 abstract 1
- 150000003536 tetrazoles Chemical class 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12126279A JPS5645414A (en) | 1979-09-19 | 1979-09-19 | Phosphodiesterase inhibitor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12126279A JPS5645414A (en) | 1979-09-19 | 1979-09-19 | Phosphodiesterase inhibitor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5645414A true JPS5645414A (en) | 1981-04-25 |
| JPS6258336B2 JPS6258336B2 (enrdf_load_stackoverflow) | 1987-12-05 |
Family
ID=14806892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12126279A Granted JPS5645414A (en) | 1979-09-19 | 1979-09-19 | Phosphodiesterase inhibitor |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5645414A (enrdf_load_stackoverflow) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5008274A (en) * | 1986-04-02 | 1991-04-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof and pharmaceutical composition for inhibiting adhesion of thrombocytes |
| WO1991010419A1 (en) * | 1990-01-08 | 1991-07-25 | Otsuka Pharmaceutical Co., Ltd. | Hair tonic and dressing composition |
| WO1994014444A1 (en) * | 1992-12-24 | 1994-07-07 | Otsuka Pharmaceutical Co., Ltd. | Psoriasis remedy |
| US5434164A (en) * | 1986-04-02 | 1995-07-18 | Otsuka Pharmaceutical Co. Ltd. | Carbostyril derivatives and salts thereof and pharmaceutical compositions for inhibiting adhesion of thrombocytes |
| US6630590B1 (en) * | 1999-11-24 | 2003-10-07 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| US7026486B2 (en) | 2002-09-10 | 2006-04-11 | Otsuka Pharmaceutical Co., Ltd. | Process for production cilostazol |
| US7399864B2 (en) * | 2001-05-02 | 2008-07-15 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| US7825251B2 (en) | 2001-05-02 | 2010-11-02 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
-
1979
- 1979-09-19 JP JP12126279A patent/JPS5645414A/ja active Granted
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5008274A (en) * | 1986-04-02 | 1991-04-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof and pharmaceutical composition for inhibiting adhesion of thrombocytes |
| US5434164A (en) * | 1986-04-02 | 1995-07-18 | Otsuka Pharmaceutical Co. Ltd. | Carbostyril derivatives and salts thereof and pharmaceutical compositions for inhibiting adhesion of thrombocytes |
| WO1991010419A1 (en) * | 1990-01-08 | 1991-07-25 | Otsuka Pharmaceutical Co., Ltd. | Hair tonic and dressing composition |
| EP0463173B1 (en) * | 1990-01-08 | 1994-12-07 | Otsuka Pharmaceutical Co., Ltd. | Hair tonic and dressing composition |
| WO1994014444A1 (en) * | 1992-12-24 | 1994-07-07 | Otsuka Pharmaceutical Co., Ltd. | Psoriasis remedy |
| US6630590B1 (en) * | 1999-11-24 | 2003-10-07 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| US7399864B2 (en) * | 2001-05-02 | 2008-07-15 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| US7825251B2 (en) | 2001-05-02 | 2010-11-02 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| US7026486B2 (en) | 2002-09-10 | 2006-04-11 | Otsuka Pharmaceutical Co., Ltd. | Process for production cilostazol |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6258336B2 (enrdf_load_stackoverflow) | 1987-12-05 |
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