JPS562974A - 1-substituted benzodiazepine derivative, its salt, and its novel preparation - Google Patents
1-substituted benzodiazepine derivative, its salt, and its novel preparationInfo
- Publication number
- JPS562974A JPS562974A JP7699379A JP7699379A JPS562974A JP S562974 A JPS562974 A JP S562974A JP 7699379 A JP7699379 A JP 7699379A JP 7699379 A JP7699379 A JP 7699379A JP S562974 A JPS562974 A JP S562974A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- formula
- benzodiazepine derivative
- novel preparation
- benzodiazepin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: To obtain the titled composition useful as a drug having sadative, muscle relaxant, and hypnotic action, etc. by reacting a 1-unsubstituted-1,4-benzodiazepine-2-one with a lower alkylvinylsulfone.
CONSTITUTION: A 1-unsubstituted-1,4-benzodiazepin-2-one, e.g., a bensodiazepine derivative shown by the formula I (R1 is H, halogen, nitro, etc.; R2 and R3 are H, halogen, or lower alkyl) is reacted with a lower alkylvinysulfone shown by the formula II (R4 is lower alkyl) in a solvent, e.g., methanol, preferably in the presence of a catalyst, e.g., sodium methylate at room temperatures or under heating to give a 1-(β-lower alkylsulfonylethyl)-1,4-benzodiazepin-2-one, e.g., a 1-substituted benzodiazepine derivative shown by the formula III.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7699379A JPS562974A (en) | 1979-06-18 | 1979-06-18 | 1-substituted benzodiazepine derivative, its salt, and its novel preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7699379A JPS562974A (en) | 1979-06-18 | 1979-06-18 | 1-substituted benzodiazepine derivative, its salt, and its novel preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS562974A true JPS562974A (en) | 1981-01-13 |
Family
ID=13621294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7699379A Pending JPS562974A (en) | 1979-06-18 | 1979-06-18 | 1-substituted benzodiazepine derivative, its salt, and its novel preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS562974A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4973315A (en) * | 1987-11-11 | 1990-11-27 | Ausmedics Pty Ltd. | Removal and safe disposal of sharps from medical tools |
-
1979
- 1979-06-18 JP JP7699379A patent/JPS562974A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4973315A (en) * | 1987-11-11 | 1990-11-27 | Ausmedics Pty Ltd. | Removal and safe disposal of sharps from medical tools |
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