JPS562960A - Pyrrolidinylalkylcarboxylic acid amide derivative* its manufacture and medicinal composition - Google Patents
Pyrrolidinylalkylcarboxylic acid amide derivative* its manufacture and medicinal compositionInfo
- Publication number
- JPS562960A JPS562960A JP7846680A JP7846680A JPS562960A JP S562960 A JPS562960 A JP S562960A JP 7846680 A JP7846680 A JP 7846680A JP 7846680 A JP7846680 A JP 7846680A JP S562960 A JPS562960 A JP S562960A
- Authority
- JP
- Japan
- Prior art keywords
- manufacture
- acid amide
- medicinal composition
- amide derivative
- pyrrolidinylalkylcarboxylic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001408 amides Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19792923975 DE2923975A1 (de) | 1979-06-13 | 1979-06-13 | Pyrrolidinone, verfahren zu deren herstellung und diese enthaltende arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS562960A true JPS562960A (en) | 1981-01-13 |
JPS625404B2 JPS625404B2 (enrdf_load_stackoverflow) | 1987-02-04 |
Family
ID=6073167
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7846680A Granted JPS562960A (en) | 1979-06-13 | 1980-06-12 | Pyrrolidinylalkylcarboxylic acid amide derivative* its manufacture and medicinal composition |
JP61061971A Granted JPS61280470A (ja) | 1979-06-13 | 1986-03-19 | ピロリジニルアルキルカルボン酸アミド誘導体およびその製造方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP61061971A Granted JPS61280470A (ja) | 1979-06-13 | 1986-03-19 | ピロリジニルアルキルカルボン酸アミド誘導体およびその製造方法 |
Country Status (2)
Country | Link |
---|---|
JP (2) | JPS562960A (enrdf_load_stackoverflow) |
DE (1) | DE2923975A1 (enrdf_load_stackoverflow) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5824558A (ja) * | 1981-07-24 | 1983-02-14 | エフ・ホフマン―ラ ロシユ アーゲー | ピロリジン誘導体 |
WO1996029308A1 (fr) * | 1995-03-23 | 1996-09-26 | Daiichi Pharmaceutical Co., Ltd. | Cristaux anhydres |
WO1999003466A1 (fr) * | 1997-07-15 | 1999-01-28 | Daiichi Pharmaceutical Co., Ltd. | Substance prophylactique ou therapeutique contre l'amnesie |
US6417220B2 (en) | 1996-10-01 | 2002-07-09 | Daiichi Pharmaceutical Co., Ltd. | Mitochondrial membrane stabilizer |
US7608636B2 (en) | 2000-12-28 | 2009-10-27 | Hamilton Pharmaceuticals, Inc. | Medicines for treatment and prevention of neurogenic pain |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2515179A1 (fr) * | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique |
DE3326724A1 (de) * | 1983-07-25 | 1985-02-07 | Boehringer Ingelheim KG, 6507 Ingelheim | In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte |
DE3336024A1 (de) * | 1983-10-04 | 1985-04-18 | Boehringer Ingelheim KG, 6507 Ingelheim | 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel |
DE3813416A1 (de) * | 1988-04-21 | 1989-11-02 | Hoechst Ag | 3,4-dihydroxypyrrolidin-2-on-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte |
CH680293A5 (enrdf_load_stackoverflow) * | 1990-06-26 | 1992-07-31 | Lonza Ag | |
US6423739B1 (en) | 2000-02-23 | 2002-07-23 | Daiichi Pharmaceutical Co., Ltd. | Method for aiding cerebral recovery following neurodegeneration |
-
1979
- 1979-06-13 DE DE19792923975 patent/DE2923975A1/de active Granted
-
1980
- 1980-06-12 JP JP7846680A patent/JPS562960A/ja active Granted
-
1986
- 1986-03-19 JP JP61061971A patent/JPS61280470A/ja active Granted
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5824558A (ja) * | 1981-07-24 | 1983-02-14 | エフ・ホフマン―ラ ロシユ アーゲー | ピロリジン誘導体 |
WO1996029308A1 (fr) * | 1995-03-23 | 1996-09-26 | Daiichi Pharmaceutical Co., Ltd. | Cristaux anhydres |
US6417220B2 (en) | 1996-10-01 | 2002-07-09 | Daiichi Pharmaceutical Co., Ltd. | Mitochondrial membrane stabilizer |
WO1999003466A1 (fr) * | 1997-07-15 | 1999-01-28 | Daiichi Pharmaceutical Co., Ltd. | Substance prophylactique ou therapeutique contre l'amnesie |
US6281242B1 (en) | 1997-07-15 | 2001-08-28 | Daiichi Pharmaceutical Co., Ltd. | Prophylactic or therapeutic agent for amnesia |
US7608636B2 (en) | 2000-12-28 | 2009-10-27 | Hamilton Pharmaceuticals, Inc. | Medicines for treatment and prevention of neurogenic pain |
Also Published As
Publication number | Publication date |
---|---|
JPS625404B2 (enrdf_load_stackoverflow) | 1987-02-04 |
DE2923975A1 (de) | 1980-12-18 |
JPH0346466B2 (enrdf_load_stackoverflow) | 1991-07-16 |
JPS61280470A (ja) | 1986-12-11 |
DE2923975C2 (enrdf_load_stackoverflow) | 1988-07-21 |
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