JPS562960A - Pyrrolidinylalkylcarboxylic acid amide derivative* its manufacture and medicinal composition - Google Patents

Pyrrolidinylalkylcarboxylic acid amide derivative* its manufacture and medicinal composition

Info

Publication number
JPS562960A
JPS562960A JP7846680A JP7846680A JPS562960A JP S562960 A JPS562960 A JP S562960A JP 7846680 A JP7846680 A JP 7846680A JP 7846680 A JP7846680 A JP 7846680A JP S562960 A JPS562960 A JP S562960A
Authority
JP
Japan
Prior art keywords
manufacture
acid amide
medicinal composition
amide derivative
pyrrolidinylalkylcarboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7846680A
Other languages
English (en)
Japanese (ja)
Other versions
JPS625404B2 (enrdf_load_stackoverflow
Inventor
Betsuingu Hansu
Biideruman Yurugen
Materune Karushiyuten
Noizeru Horukeru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
A Natterman und Cie GmbH
Original Assignee
A Natterman und Cie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A Natterman und Cie GmbH filed Critical A Natterman und Cie GmbH
Publication of JPS562960A publication Critical patent/JPS562960A/ja
Publication of JPS625404B2 publication Critical patent/JPS625404B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2632-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/272-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP7846680A 1979-06-13 1980-06-12 Pyrrolidinylalkylcarboxylic acid amide derivative* its manufacture and medicinal composition Granted JPS562960A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792923975 DE2923975A1 (de) 1979-06-13 1979-06-13 Pyrrolidinone, verfahren zu deren herstellung und diese enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
JPS562960A true JPS562960A (en) 1981-01-13
JPS625404B2 JPS625404B2 (enrdf_load_stackoverflow) 1987-02-04

Family

ID=6073167

Family Applications (2)

Application Number Title Priority Date Filing Date
JP7846680A Granted JPS562960A (en) 1979-06-13 1980-06-12 Pyrrolidinylalkylcarboxylic acid amide derivative* its manufacture and medicinal composition
JP61061971A Granted JPS61280470A (ja) 1979-06-13 1986-03-19 ピロリジニルアルキルカルボン酸アミド誘導体およびその製造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP61061971A Granted JPS61280470A (ja) 1979-06-13 1986-03-19 ピロリジニルアルキルカルボン酸アミド誘導体およびその製造方法

Country Status (2)

Country Link
JP (2) JPS562960A (enrdf_load_stackoverflow)
DE (1) DE2923975A1 (enrdf_load_stackoverflow)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5824558A (ja) * 1981-07-24 1983-02-14 エフ・ホフマン―ラ ロシユ アーゲー ピロリジン誘導体
WO1996029308A1 (fr) * 1995-03-23 1996-09-26 Daiichi Pharmaceutical Co., Ltd. Cristaux anhydres
WO1999003466A1 (fr) * 1997-07-15 1999-01-28 Daiichi Pharmaceutical Co., Ltd. Substance prophylactique ou therapeutique contre l'amnesie
US6417220B2 (en) 1996-10-01 2002-07-09 Daiichi Pharmaceutical Co., Ltd. Mitochondrial membrane stabilizer
US7608636B2 (en) 2000-12-28 2009-10-27 Hamilton Pharmaceuticals, Inc. Medicines for treatment and prevention of neurogenic pain

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
DE3326724A1 (de) * 1983-07-25 1985-02-07 Boehringer Ingelheim KG, 6507 Ingelheim In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3813416A1 (de) * 1988-04-21 1989-11-02 Hoechst Ag 3,4-dihydroxypyrrolidin-2-on-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte
CH680293A5 (enrdf_load_stackoverflow) * 1990-06-26 1992-07-31 Lonza Ag
US6423739B1 (en) 2000-02-23 2002-07-23 Daiichi Pharmaceutical Co., Ltd. Method for aiding cerebral recovery following neurodegeneration

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5824558A (ja) * 1981-07-24 1983-02-14 エフ・ホフマン―ラ ロシユ アーゲー ピロリジン誘導体
WO1996029308A1 (fr) * 1995-03-23 1996-09-26 Daiichi Pharmaceutical Co., Ltd. Cristaux anhydres
US6417220B2 (en) 1996-10-01 2002-07-09 Daiichi Pharmaceutical Co., Ltd. Mitochondrial membrane stabilizer
WO1999003466A1 (fr) * 1997-07-15 1999-01-28 Daiichi Pharmaceutical Co., Ltd. Substance prophylactique ou therapeutique contre l'amnesie
US6281242B1 (en) 1997-07-15 2001-08-28 Daiichi Pharmaceutical Co., Ltd. Prophylactic or therapeutic agent for amnesia
US7608636B2 (en) 2000-12-28 2009-10-27 Hamilton Pharmaceuticals, Inc. Medicines for treatment and prevention of neurogenic pain

Also Published As

Publication number Publication date
JPS625404B2 (enrdf_load_stackoverflow) 1987-02-04
DE2923975A1 (de) 1980-12-18
JPH0346466B2 (enrdf_load_stackoverflow) 1991-07-16
JPS61280470A (ja) 1986-12-11
DE2923975C2 (enrdf_load_stackoverflow) 1988-07-21

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