JPS5620591A - Novel oxazolobenzodiazepine derivative and preparation of tricyclic benzodiazepine compound comprising the same - Google Patents
Novel oxazolobenzodiazepine derivative and preparation of tricyclic benzodiazepine compound comprising the sameInfo
- Publication number
- JPS5620591A JPS5620591A JP9582879A JP9582879A JPS5620591A JP S5620591 A JPS5620591 A JP S5620591A JP 9582879 A JP9582879 A JP 9582879A JP 9582879 A JP9582879 A JP 9582879A JP S5620591 A JPS5620591 A JP S5620591A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- novel
- oxazolobenzodiazepine
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: To obtain a tricyclic benzodiazepine compound which is a central nervous system depressant with low toxicity readily in high yield, by oxidizing a novel oxazolobenzodiazepine derivative prepared by various methods.
CONSTITUTION: A compound of formula II (R1 and R2 are H, NO2 group, halogen, etc.; R3 is H or lower alkyl group; R5 is H, lower alkyl group, etc.) is reacted with a compound of formula III (R4 is H or lower alkyl) to give a novel compound of formula I, which is then oxidized with chromic acid or manganese oxide in water or an organic solvent at room temperature to form a compound of formula IV. The compound of formula I is not only an intermediate for the compound of formula IV but also useful as a sedative agent or a tranquilizer per se.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9582879A JPS5620591A (en) | 1979-07-27 | 1979-07-27 | Novel oxazolobenzodiazepine derivative and preparation of tricyclic benzodiazepine compound comprising the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9582879A JPS5620591A (en) | 1979-07-27 | 1979-07-27 | Novel oxazolobenzodiazepine derivative and preparation of tricyclic benzodiazepine compound comprising the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5620591A true JPS5620591A (en) | 1981-02-26 |
Family
ID=14148253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9582879A Pending JPS5620591A (en) | 1979-07-27 | 1979-07-27 | Novel oxazolobenzodiazepine derivative and preparation of tricyclic benzodiazepine compound comprising the same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5620591A (en) |
-
1979
- 1979-07-27 JP JP9582879A patent/JPS5620591A/en active Pending
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