JPS5619000A - 3beta. 25-dihydroxy-24-oxocholesta-5,7-diene derivative and its preparation - Google Patents

3beta. 25-dihydroxy-24-oxocholesta-5,7-diene derivative and its preparation

Info

Publication number
JPS5619000A
JPS5619000A JP9418479A JP9418479A JPS5619000A JP S5619000 A JPS5619000 A JP S5619000A JP 9418479 A JP9418479 A JP 9418479A JP 9418479 A JP9418479 A JP 9418479A JP S5619000 A JPS5619000 A JP S5619000A
Authority
JP
Japan
Prior art keywords
formula
pref
oxocholesta
3beta
dihydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9418479A
Other languages
Japanese (ja)
Inventor
Osamu Nishikawa
Kenji Ishimaru
Toru Takeshita
Hideki Tsuruta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP9418479A priority Critical patent/JPS5619000A/en
Publication of JPS5619000A publication Critical patent/JPS5619000A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Steroid Compounds (AREA)

Abstract

NEW MATERIAL:The titled derivative of formula I (R1,R3 are H or OH-protecting group; R2 is H, OH or protected OH).
USE: Intermediate of active-type vitamin D3.
PROCESS: A compound of formula I wherein OR3 is OH is prepared by oxidizing, e.g. 1mol of a 3β-hydroxy-24-oxochlesta-5,7-diene derivative of formula II with oxygen in the presence of pref. 1W10mol of a basic compound such as sodium t-butoxide, pref. in an organic liquid such as benzene. The oxidation reaction is pref. carried out in a closed system by introducing and dissolving 0.5W2mol of oxygen in 1mol of the compound of formula II while stirring at -20 W+20°C.
COPYRIGHT: (C)1981,JPO&Japio
JP9418479A 1979-07-26 1979-07-26 3beta. 25-dihydroxy-24-oxocholesta-5,7-diene derivative and its preparation Pending JPS5619000A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9418479A JPS5619000A (en) 1979-07-26 1979-07-26 3beta. 25-dihydroxy-24-oxocholesta-5,7-diene derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9418479A JPS5619000A (en) 1979-07-26 1979-07-26 3beta. 25-dihydroxy-24-oxocholesta-5,7-diene derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5619000A true JPS5619000A (en) 1981-02-23

Family

ID=14103224

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9418479A Pending JPS5619000A (en) 1979-07-26 1979-07-26 3beta. 25-dihydroxy-24-oxocholesta-5,7-diene derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5619000A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022501348A (en) * 2018-09-19 2022-01-06 モデルナティエックス インコーポレイテッドModernaTX, Inc. Sterol analogs and their use

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022501348A (en) * 2018-09-19 2022-01-06 モデルナティエックス インコーポレイテッドModernaTX, Inc. Sterol analogs and their use
EP3852764A4 (en) * 2018-09-19 2022-06-15 ModernaTX, Inc. Sterol analogs and uses thereof

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