JPS55153780A - Sesquiterpene derivative compound - Google Patents

Sesquiterpene derivative compound

Info

Publication number
JPS55153780A
JPS55153780A JP4533980A JP4533980A JPS55153780A JP S55153780 A JPS55153780 A JP S55153780A JP 4533980 A JP4533980 A JP 4533980A JP 4533980 A JP4533980 A JP 4533980A JP S55153780 A JPS55153780 A JP S55153780A
Authority
JP
Japan
Prior art keywords
compound
formula
nabh
treated
derivative compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4533980A
Other languages
Japanese (ja)
Other versions
JPS5850222B2 (en
Inventor
Hiroyuki Akita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIKEN Institute of Physical and Chemical Research
Original Assignee
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIKEN Institute of Physical and Chemical Research filed Critical RIKEN Institute of Physical and Chemical Research
Priority to JP4533980A priority Critical patent/JPS5850222B2/en
Publication of JPS55153780A publication Critical patent/JPS55153780A/en
Publication of JPS5850222B2 publication Critical patent/JPS5850222B2/en
Expired legal-status Critical Current

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  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:11-Hydroxy-drim-8-ene-12,13-dioic acid 13-methyl ester 11→12- lactone of formula I.
USE: An antifungal against viable dermatophytes.
PROCESS: A compound of formula II (R is H or isopropyl group) is oxidized with a large excess of ozone to cleave the aromatic ring. The oxidation product is then treated with a reducing agent to give the compound of formula I. In case 10% Pd-C or sodium sulfite is used as the agent, the first product hydroxylactone is treated with NaBH4 to form the objective compound. The use of NaBH4 from the beginning provides the compound readily.
COPYRIGHT: (C)1980,JPO&Japio
JP4533980A 1980-04-07 1980-04-07 Sesquiterpene derivative compounds Expired JPS5850222B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4533980A JPS5850222B2 (en) 1980-04-07 1980-04-07 Sesquiterpene derivative compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4533980A JPS5850222B2 (en) 1980-04-07 1980-04-07 Sesquiterpene derivative compounds

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP10838676A Division JPS5334768A (en) 1976-09-09 1976-09-09 Preparation of diterpene derivatives

Publications (2)

Publication Number Publication Date
JPS55153780A true JPS55153780A (en) 1980-11-29
JPS5850222B2 JPS5850222B2 (en) 1983-11-09

Family

ID=12716529

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4533980A Expired JPS5850222B2 (en) 1980-04-07 1980-04-07 Sesquiterpene derivative compounds

Country Status (1)

Country Link
JP (1) JPS5850222B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444235B1 (en) * 1999-10-06 2002-09-03 Bioactiva Microtechne Canelo products and methods of making and using same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444235B1 (en) * 1999-10-06 2002-09-03 Bioactiva Microtechne Canelo products and methods of making and using same

Also Published As

Publication number Publication date
JPS5850222B2 (en) 1983-11-09

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