JPS55153780A - Sesquiterpene derivative compound - Google Patents
Sesquiterpene derivative compoundInfo
- Publication number
- JPS55153780A JPS55153780A JP4533980A JP4533980A JPS55153780A JP S55153780 A JPS55153780 A JP S55153780A JP 4533980 A JP4533980 A JP 4533980A JP 4533980 A JP4533980 A JP 4533980A JP S55153780 A JPS55153780 A JP S55153780A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- nabh
- treated
- derivative compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:11-Hydroxy-drim-8-ene-12,13-dioic acid 13-methyl ester 11→12- lactone of formula I.
USE: An antifungal against viable dermatophytes.
PROCESS: A compound of formula II (R is H or isopropyl group) is oxidized with a large excess of ozone to cleave the aromatic ring. The oxidation product is then treated with a reducing agent to give the compound of formula I. In case 10% Pd-C or sodium sulfite is used as the agent, the first product hydroxylactone is treated with NaBH4 to form the objective compound. The use of NaBH4 from the beginning provides the compound readily.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4533980A JPS5850222B2 (en) | 1980-04-07 | 1980-04-07 | Sesquiterpene derivative compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4533980A JPS5850222B2 (en) | 1980-04-07 | 1980-04-07 | Sesquiterpene derivative compounds |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10838676A Division JPS5334768A (en) | 1976-09-09 | 1976-09-09 | Preparation of diterpene derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55153780A true JPS55153780A (en) | 1980-11-29 |
JPS5850222B2 JPS5850222B2 (en) | 1983-11-09 |
Family
ID=12716529
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4533980A Expired JPS5850222B2 (en) | 1980-04-07 | 1980-04-07 | Sesquiterpene derivative compounds |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5850222B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6444235B1 (en) * | 1999-10-06 | 2002-09-03 | Bioactiva Microtechne | Canelo products and methods of making and using same |
-
1980
- 1980-04-07 JP JP4533980A patent/JPS5850222B2/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6444235B1 (en) * | 1999-10-06 | 2002-09-03 | Bioactiva Microtechne | Canelo products and methods of making and using same |
Also Published As
Publication number | Publication date |
---|---|
JPS5850222B2 (en) | 1983-11-09 |
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