JPS56161368A - Novel trans-vitamin d derivative - Google Patents

Novel trans-vitamin d derivative

Info

Publication number
JPS56161368A
JPS56161368A JP6403980A JP6403980A JPS56161368A JP S56161368 A JPS56161368 A JP S56161368A JP 6403980 A JP6403980 A JP 6403980A JP 6403980 A JP6403980 A JP 6403980A JP S56161368 A JPS56161368 A JP S56161368A
Authority
JP
Japan
Prior art keywords
iodine
vitamin
reaction mixture
derivative
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6403980A
Other languages
Japanese (ja)
Inventor
Tatsuo Suda
Sachiko Yamada
Hiroaki Takayama
Yoshiko Takasaki
Yasuho Nishii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP6403980A priority Critical patent/JPS56161368A/en
Publication of JPS56161368A publication Critical patent/JPS56161368A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:(24R)-24, 25-Dihydroxy-5,6-trans-vitamin D3.
USE: Effective for calcium dysbolism of a nephrectomized animal, etc. and advantageous over the well-knwon compound due to no trouble in preparation.
PROCESS: (24R)-24, 25-Dihydroxyvitamin D3 is brought into contact with iodine in an inert solvent and isomerized to give the titled compound. A hydrocarbon solvent, e.g. hexane or pentane, is preferably used as the inert solvent, and the amount of the iodine varies with the amount of the raw material and the reaction conditions. The iodine is removed from the reaction mixture by the conventional method, and the reaction mixture is extracted and subjected to the high speed chromatography to isolate the titled compound.
COPYRIGHT: (C)1981,JPO&Japio
JP6403980A 1980-05-16 1980-05-16 Novel trans-vitamin d derivative Pending JPS56161368A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6403980A JPS56161368A (en) 1980-05-16 1980-05-16 Novel trans-vitamin d derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6403980A JPS56161368A (en) 1980-05-16 1980-05-16 Novel trans-vitamin d derivative

Publications (1)

Publication Number Publication Date
JPS56161368A true JPS56161368A (en) 1981-12-11

Family

ID=13246569

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6403980A Pending JPS56161368A (en) 1980-05-16 1980-05-16 Novel trans-vitamin d derivative

Country Status (1)

Country Link
JP (1) JPS56161368A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001030751A3 (en) * 1999-10-25 2002-06-13 Strakan Ltd USES OF 1,25-DIHYDROXY-5,6-trans VITAMIN D COMPOUNDS AND DERIVATIVES THEREOF

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51128417A (en) * 1975-04-28 1976-11-09 Teijin Ltd A method for stabilizing active vitamin d3 derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51128417A (en) * 1975-04-28 1976-11-09 Teijin Ltd A method for stabilizing active vitamin d3 derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001030751A3 (en) * 1999-10-25 2002-06-13 Strakan Ltd USES OF 1,25-DIHYDROXY-5,6-trans VITAMIN D COMPOUNDS AND DERIVATIVES THEREOF

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