JPS56131395A - Purification of coenzyme q - Google Patents
Purification of coenzyme qInfo
- Publication number
- JPS56131395A JPS56131395A JP3514680A JP3514680A JPS56131395A JP S56131395 A JPS56131395 A JP S56131395A JP 3514680 A JP3514680 A JP 3514680A JP 3514680 A JP3514680 A JP 3514680A JP S56131395 A JPS56131395 A JP S56131395A
- Authority
- JP
- Japan
- Prior art keywords
- coenzyme
- nonpolar solvent
- ketone
- mixture
- silica gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To obtain a high-purity coenzyme Q in high yield industrially advantageously, by purifying crude coenzyme Q by silica gel chromatography using a developing agent consisting of a mixture of an aliphatic ketone and a nonpolar solvent.
CONSTITUTION: Silica gel is fed to a column using a mixture of 10W50vol% aliphatic ketone (e.g., acetone, methyl ethyl ketone etc.) and a nonpolar solvent (e.g., n-hexane, n-pentane, etc.), and it is replaced by a mixture of an aliphatic kethone having an aliphtic ketone content not less than 0.2vol% in a volume not more than that used in development and a nonpolar solvent. The silica gel is charged with crude coenzyme Q dissolved in a developing solvent cosisting of 0.3W20vol% aliphatic ketone and a nonpolar solvent and the developing solvent is made to flow continuously so that coenzyme Q is eluted.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3514680A JPS56131395A (en) | 1980-03-19 | 1980-03-19 | Purification of coenzyme q |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3514680A JPS56131395A (en) | 1980-03-19 | 1980-03-19 | Purification of coenzyme q |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56131395A true JPS56131395A (en) | 1981-10-14 |
JPS5721309B2 JPS5721309B2 (en) | 1982-05-06 |
Family
ID=12433757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3514680A Granted JPS56131395A (en) | 1980-03-19 | 1980-03-19 | Purification of coenzyme q |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56131395A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007126086A1 (en) * | 2006-04-28 | 2007-11-08 | Kaneka Corporation | Method for purification of reduced coenzyme q10 |
-
1980
- 1980-03-19 JP JP3514680A patent/JPS56131395A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007126086A1 (en) * | 2006-04-28 | 2007-11-08 | Kaneka Corporation | Method for purification of reduced coenzyme q10 |
JPWO2007126086A1 (en) * | 2006-04-28 | 2009-09-10 | 株式会社カネカ | Purification method of reduced coenzyme Q10 |
Also Published As
Publication number | Publication date |
---|---|
JPS5721309B2 (en) | 1982-05-06 |
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