JPS56131395A - Purification of coenzyme q - Google Patents

Purification of coenzyme q

Info

Publication number
JPS56131395A
JPS56131395A JP3514680A JP3514680A JPS56131395A JP S56131395 A JPS56131395 A JP S56131395A JP 3514680 A JP3514680 A JP 3514680A JP 3514680 A JP3514680 A JP 3514680A JP S56131395 A JPS56131395 A JP S56131395A
Authority
JP
Japan
Prior art keywords
coenzyme
nonpolar solvent
ketone
mixture
silica gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3514680A
Other languages
Japanese (ja)
Other versions
JPS5721309B2 (en
Inventor
Sadaji Uragami
Sumiyasu Takano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Gas Chemical Co Inc
Original Assignee
Mitsubishi Gas Chemical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Gas Chemical Co Inc filed Critical Mitsubishi Gas Chemical Co Inc
Priority to JP3514680A priority Critical patent/JPS56131395A/en
Publication of JPS56131395A publication Critical patent/JPS56131395A/en
Publication of JPS5721309B2 publication Critical patent/JPS5721309B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To obtain a high-purity coenzyme Q in high yield industrially advantageously, by purifying crude coenzyme Q by silica gel chromatography using a developing agent consisting of a mixture of an aliphatic ketone and a nonpolar solvent.
CONSTITUTION: Silica gel is fed to a column using a mixture of 10W50vol% aliphatic ketone (e.g., acetone, methyl ethyl ketone etc.) and a nonpolar solvent (e.g., n-hexane, n-pentane, etc.), and it is replaced by a mixture of an aliphatic kethone having an aliphtic ketone content not less than 0.2vol% in a volume not more than that used in development and a nonpolar solvent. The silica gel is charged with crude coenzyme Q dissolved in a developing solvent cosisting of 0.3W20vol% aliphatic ketone and a nonpolar solvent and the developing solvent is made to flow continuously so that coenzyme Q is eluted.
COPYRIGHT: (C)1981,JPO&Japio
JP3514680A 1980-03-19 1980-03-19 Purification of coenzyme q Granted JPS56131395A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3514680A JPS56131395A (en) 1980-03-19 1980-03-19 Purification of coenzyme q

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3514680A JPS56131395A (en) 1980-03-19 1980-03-19 Purification of coenzyme q

Publications (2)

Publication Number Publication Date
JPS56131395A true JPS56131395A (en) 1981-10-14
JPS5721309B2 JPS5721309B2 (en) 1982-05-06

Family

ID=12433757

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3514680A Granted JPS56131395A (en) 1980-03-19 1980-03-19 Purification of coenzyme q

Country Status (1)

Country Link
JP (1) JPS56131395A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007126086A1 (en) * 2006-04-28 2007-11-08 Kaneka Corporation Method for purification of reduced coenzyme q10

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007126086A1 (en) * 2006-04-28 2007-11-08 Kaneka Corporation Method for purification of reduced coenzyme q10
JPWO2007126086A1 (en) * 2006-04-28 2009-09-10 株式会社カネカ Purification method of reduced coenzyme Q10

Also Published As

Publication number Publication date
JPS5721309B2 (en) 1982-05-06

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