JPS56115775A - Preparation of dihydroxymethylpyridine dicarbamate - Google Patents

Preparation of dihydroxymethylpyridine dicarbamate

Info

Publication number
JPS56115775A
JPS56115775A JP1926180A JP1926180A JPS56115775A JP S56115775 A JPS56115775 A JP S56115775A JP 1926180 A JP1926180 A JP 1926180A JP 1926180 A JP1926180 A JP 1926180A JP S56115775 A JPS56115775 A JP S56115775A
Authority
JP
Japan
Prior art keywords
dihydroxymethylpyridine
formula
dimethanolpyridine
carbonyldiamidate
reacted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1926180A
Other languages
Japanese (ja)
Other versions
JPS5719104B2 (en
Inventor
Koichi Iwase
Keisuke Iwai
Nobuo Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHIBA GOSEI KENKYUSHO KK
CHIBA GOUSEI KENKYUSHO KK
SHINSEN IYAKU KK
Original Assignee
CHIBA GOSEI KENKYUSHO KK
CHIBA GOUSEI KENKYUSHO KK
SHINSEN IYAKU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHIBA GOSEI KENKYUSHO KK, CHIBA GOUSEI KENKYUSHO KK, SHINSEN IYAKU KK filed Critical CHIBA GOSEI KENKYUSHO KK
Priority to JP1926180A priority Critical patent/JPS56115775A/en
Publication of JPS56115775A publication Critical patent/JPS56115775A/en
Publication of JPS5719104B2 publication Critical patent/JPS5719104B2/ja
Granted legal-status Critical Current

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  • Pyridine Compounds (AREA)

Abstract

PURPOSE: To obtain the titled compound useful as a preventing agent against thrombosis industirally and advantageously, by reacting a 2,6-dimethanolpyridine with a carbonyldiamidate, e.g. diimidazole carbonate, and then reacting the resultant intermediate with an amine.
CONSTITUTION: 2,6-Dimethanolpyridine is reacted with a carbonyldiamidate expressed by formula I (N is a heterocyclic compound containing nitrogen), preferably diimidazole carbonate which is reactive and readily available, to give a reactive heterocyclic ring carbamate intermediate containing nitrogen, which is then reacted with an amine of formula II (R1 and R2 are H or lower alkyl), e.g. methylamine, to afford a dihydroxymethylphridine carbamate of formula III, e.g. 2,6-dihydroxymethylpyridine di-N-methylcarbamate.
COPYRIGHT: (C)1981,JPO&Japio
JP1926180A 1980-02-20 1980-02-20 Preparation of dihydroxymethylpyridine dicarbamate Granted JPS56115775A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1926180A JPS56115775A (en) 1980-02-20 1980-02-20 Preparation of dihydroxymethylpyridine dicarbamate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1926180A JPS56115775A (en) 1980-02-20 1980-02-20 Preparation of dihydroxymethylpyridine dicarbamate

Publications (2)

Publication Number Publication Date
JPS56115775A true JPS56115775A (en) 1981-09-11
JPS5719104B2 JPS5719104B2 (en) 1982-04-20

Family

ID=11994489

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1926180A Granted JPS56115775A (en) 1980-02-20 1980-02-20 Preparation of dihydroxymethylpyridine dicarbamate

Country Status (1)

Country Link
JP (1) JPS56115775A (en)

Also Published As

Publication number Publication date
JPS5719104B2 (en) 1982-04-20

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