JPS56115775A - Preparation of dihydroxymethylpyridine dicarbamate - Google Patents
Preparation of dihydroxymethylpyridine dicarbamateInfo
- Publication number
- JPS56115775A JPS56115775A JP1926180A JP1926180A JPS56115775A JP S56115775 A JPS56115775 A JP S56115775A JP 1926180 A JP1926180 A JP 1926180A JP 1926180 A JP1926180 A JP 1926180A JP S56115775 A JPS56115775 A JP S56115775A
- Authority
- JP
- Japan
- Prior art keywords
- dihydroxymethylpyridine
- formula
- dimethanolpyridine
- carbonyldiamidate
- reacted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pyridine Compounds (AREA)
Abstract
PURPOSE: To obtain the titled compound useful as a preventing agent against thrombosis industirally and advantageously, by reacting a 2,6-dimethanolpyridine with a carbonyldiamidate, e.g. diimidazole carbonate, and then reacting the resultant intermediate with an amine.
CONSTITUTION: 2,6-Dimethanolpyridine is reacted with a carbonyldiamidate expressed by formula I (N is a heterocyclic compound containing nitrogen), preferably diimidazole carbonate which is reactive and readily available, to give a reactive heterocyclic ring carbamate intermediate containing nitrogen, which is then reacted with an amine of formula II (R1 and R2 are H or lower alkyl), e.g. methylamine, to afford a dihydroxymethylphridine carbamate of formula III, e.g. 2,6-dihydroxymethylpyridine di-N-methylcarbamate.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1926180A JPS56115775A (en) | 1980-02-20 | 1980-02-20 | Preparation of dihydroxymethylpyridine dicarbamate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1926180A JPS56115775A (en) | 1980-02-20 | 1980-02-20 | Preparation of dihydroxymethylpyridine dicarbamate |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56115775A true JPS56115775A (en) | 1981-09-11 |
JPS5719104B2 JPS5719104B2 (en) | 1982-04-20 |
Family
ID=11994489
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1926180A Granted JPS56115775A (en) | 1980-02-20 | 1980-02-20 | Preparation of dihydroxymethylpyridine dicarbamate |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56115775A (en) |
-
1980
- 1980-02-20 JP JP1926180A patent/JPS56115775A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS5719104B2 (en) | 1982-04-20 |
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